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Exercise Capacity And Exercise Hypertension After Surgical Repair Of Isolated Aortic Coarctation.

A. Hager, S. Kanz, H. Kaemmerer, J. Hess
Published 2008 · Medicine

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There are contradictory reports whether exercise capacity is reduced in patients on long-term follow-up after coarctation repair. Data from unselected patient groups are missing. In a cross-sectional, long-term follow-up study of a tertiary congenital cardiology referral center, 260 patients (30.2+/-11.4 years old, 84 women), after surgical repair for isolated aortic coarctation (age at surgery 11.5+/-11.2 years), underwent a symptom-limited exercise test. Peak workload was 180+/-52 W, significantly less than the age- and height-related reference values (p<0.0005). A peak workload under 80% of expected was found in 200 patients (77%). Exercise performance of the patients was independent from age at surgery, type of surgery, or the systolic brachial-ankle blood pressure difference. The only exercise-limiting factor found was the chronic administration of diuretics to treat hypertension (p=0.005). Exercise hypertension, defined as a systolic blood pressure >2 SD above the load-dependent reference value, was found in 73 patients (28%). It was independently related to the systolic brachial-ankle blood pressure difference (p<0.0005) and diuretics administration (p=0.037). In conclusion, most patients after coarctation repair have a reduced exercise performance. This reduction is not related to the surgical results. Particularly, as these patients are at risk of early atherosclerosis, exercise should be promoted as primary prevention after restenosis, aortic or cerebral aneurysms, and severe exercise hypertension are ruled out.
This paper references
Coarctation of the aorta; a review of 104 autopsied cases of the adult type, 2 years of age or older.
G. H. Reifenstein (1947)
Normwerte des arteriellen Blutdruckverhaltens während fahrradergometrischer Belastung
H. Heck (1984)
Guidelines for exercise testing. A report of the American College of Cardiology/American Heart Association Task Force on Assessment of Cardiovascular Procedures (Subcommitte on Exercise Testing).
David J. Feild (1986)
Cystic medial necrosis in coarctation of the aorta: a potential factor contributing to adverse consequences observed after percutaneous balloon angioplasty of coarctation sites.
J. Isner (1987)
Coarctation of the aorta. Long-term follow-up and prediction of outcome after surgical correction.
M. Cohen (1989)
Maximal voluntary exercise variables in children with postoperative coarctation of the aorta.
S. M. Balderston (1992)
Effects of Morphologic Restenosis, Defined by MRI After Coarctation Repair, on Blood Pressure and Arm-Leg and Doppler Gradients
J. Günthard (1996)
Excessive anaerobic metabolism during exercise after repair of aortic coarctation.
J. Rhodes (1997)
ACC/AHA guidelines for exercise testing: executive summary. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Exercise Testing).
R. Gibbons (1997)
ACC/AHA Guidelines for Exercise Testing. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Exercise Testing).
R. Gibbons (1997)
Aortic Elastic Properties in Patients With Repaired Coarctation of Aorta
S. Brili (1998)
A comparison of V˙ O2peak between patients with congenital heart disease and healthy subjects, all aged 8–17 years
P. M. Fredriksen (1999)
Exercise test in detecting anomalous behaviour of blood pressure in patients successfully operated on for coarctation of the aorta.
N. Carano (1999)
Abnormal responses for blood pressure in children and adults with surgically corrected aortic coarctation
M. Hauser (2000)
Images in Cardiovascular Medicine
C. S. Breburda (2000)
Vascular dysfunction after repair of coarctation of the aorta: Impact of Early Surgery
M. de Divitiis (2001)
Exercise standards for testing and training: a statement for healthcare professionals from the American Heart Association.
G. Fletcher (2001)
Structural Abnormalities of Great Arterial Walls in Congenital Heart Disease: Light and Electron Microscopic Analyses
K. Niwa (2001)
ACC/AHA 2002 guideline update for exercise testing: summary article. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1997 Exercise Testing Guidelines).
R. Gibbons (2002)
Blood Pressure Response to Heart Rate During Exercise Test and Risk of Future Hypertension
N. Miyai (2002)
Exercise systolic blood pressures are of questionable value in the assessment of the adult with a previous coarctation repair
L. Swan (2003)
Intracranial aneurysms in patients with coarctation of the aorta: a prospective magnetic resonance angiographic study of 100 patients.
H. Connolly (2003)
Ambulatory blood pressure, left ventricular mass, and conduit artery function late after successful repair of coarctation of the aorta.
M. de Divitiis (2003)
Reference values for the physical work capacity on a bicycle ergometer for men – a comparison with a previous study on women
B. Wohlfart (2003)
Carotid and femoral B-mode ultrasound intima-media thickness measurements in adult post-coarctectomy patients.
J. Vriend (2004)
Normality of cardiopulmonary capacity in children operated on to correct congenital heart defects.
K. Norozi (2005)
Predicting the risk of early atherosclerotic disease development in children after repair of aortic coarctation.
A. A. Meyer (2005)
Exercise Intolerance in Adult Congenital Heart Disease: Comparative Severity, Correlates, and Prognostic Implication
G. Diller (2005)
Impaired Elastic Properties of the Ascending Aorta in Newborns Before and Early After Successful Coarctation Repair: Proof of a Systemic Vascular Disease of the Prestenotic Arteries?
M. Vogt (2005)
Images in cardiovascular medicine. Giant aortic aneurysm after patch repair of coarctation.
N. Augustin (2006)
Motor development in children with congenital cardiac diseases compared to their healthy peers
B. Bjarnason-Wehrens (2007)
Quality of life and exercise capacity in 497 patients with congenital heart disease
A Gratz (2007)
Coarctation Long-term Assessment (COALA): Significance of arterial hypertension in a cohort of 404 patients up to 27 years after surgical repair of isolated coarctation of the aorta, even in the absence of restenosis and prosthetic material
T. Graham (2008)

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A. Lehnert (2019)
Exercise Capacity in Asymptomatic Adult Patients Treated for Coarctation of the Aorta
E. J. Dijkema (2019)
Disfunção vascular nos doentes com coarctação da aorta tratada
J. D. F. Martins (2019)
A Cross-Sectional Study of the Prevalence of Exercise-Induced Hypertension in Childhood Following Repair of Coarctation of the Aorta.
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P. Millar (2018)
Risk factors of mortality and recoarctation after coarctation repair in infancy
A. Lehnert (2018)
Quality of life after surgical treatment of coarctation in long-term follow-up (CoAFU): Predictive value of clinical variables.
P. Bambul Heck (2018)
Arterial Hypertension after Coarctation-Repair in Long-term Follow-up (CoAFU): Predictive Value of Clinical Variables.
P. Bambul Heck (2017)
Exercise Capacity Before and After Stent Placement for Coarctation of the Aorta: A Single-Center Case Series
Brandon D Morrical (2017)
Survival and cardiovascular events after coarctation-repair in long-term follow-up (COAFU): Predictive value of clinical variables.
P. Bambul Heck (2017)
A systematic review and meta-analysis of exercise and exercise hypertension in patients with aortic coarctation
H. Foulds (2017)
Hypertension in Coarctation of the Aorta: Challenges in Diagnosis in Children
T. Vigneswaran (2017)
Left ventricular contractile reserve in young adults long-term after repair of coarctation of the aorta.
V. W. Li (2015)
Percutaneous Treatment of Adult Isthmic Aortic Coarctation: Acute and Long-Term Clinical and Imaging Outcome With a Self-Expandable Uncovered Nitinol Stent
S. Kische (2015)
Recurrent of Aortic Coarctation in Extra-anatomical Bypass Surgery
S. Morishima (2014)
Fluid-structure interaction simulation of (repaired) aortic coarctation
L. Taelman (2014)
Intérêt de l’échographie d’effort dans le dépistage des récidives de coarctation de l’aorte
G. Deverrière (2014)
Exercise Capacity, Physical Activity, and Obesity in Adults With Repaired Aortic Coarctation
R. Buys (2013)
H. Eltchaninoff (2013)
Correlation of exercise response in repaired coarctation of the aorta to left ventricular mass and geometry.
E. Krieger (2013)
Exercise: Friend or Foe in Adult Congenital Heart Disease?
O. Tutarel (2013)
Predictors of exaggerated exercise-induced systolic blood pressures in young patients after coarctation repair
Peace C. Madueme (2012)
Isoproterenol stress test during catheterization of patients with coarctation of the aorta
K. Kim (2012)
Recommendations for physical activity, recreation sport, and exercise training in paediatric patients with congenital heart disease: a report from the Exercise, Basic & Translational Research Section of the European Association of Cardiovascular Prevention and Rehabilitation, the European Congenital
T. Takken (2012)
Exercise capacity after coarctation repair relates to the c.46A > G genomic polymorphism of the ß2-adrenoreceptor and the c.704T > C angiotensinogen polymorphism
A. Hager (2012)
Late morbidity after repair of aortic coarctation.
T. Pedersen (2012)
Prevalence and Long-Term Predictors of Left Ventricular Hypertrophy, Late Hypertension, and Hypertensive Response to Exercise After Successful Aortic Coarctation Repair
A. Bocelli (2012)
Functional health status late after surgical correction of aortic coarctation.
T. Pedersen (2011)
Langzeitverlauf des kardiologischen Gesundheitszustandes nach neonataler arterieller Switch-Operation
Annika Schulze (2011)
Congenital Heart thewith congenital heart disease : a report from the Exercise , Basic & Translational Research Section of Recommendations for physical activity , recreation sport , and exercise training in paediatric patients
A. Giardini (2011)
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