Online citations, reference lists, and bibliographies.

Optimizing Au-nanoprobes For Specific Sequence Discrimination.

Gonçalo Doria, Bernhard G. Baumgartner, Ricardo Franco, Pedro Viana Baptista
Published 2010 · Medicine, Chemistry
Cite This
Download PDF
Analyze on Scholarcy
Share
Gold nanoparticles functionalized with thiol-oligonucleotides are ideal platforms for detection of specific DNA sequences. Here we evaluate the effect of single base mismatches in hybridization efficiency according to the position of the mismatch, base pairing combination and thiol-oligonucleotide density in terms of specificity and efficiency of target recognition. Hybridization efficiency and single-nucleotide polymorphism discrimination at room temperature is maximized at a density of 83+/-4 thiol-oligonucleotides per 13.5 nm gold nanoparticle (24 pmol/cm(2)), and when the mismatch is localized at the 3'-end of the Au-nanoprobe, i.e. away from the gold nanoparticle surface.
This paper references
Chem
J. Xu (2005)
10.1039/b707182e
Benchmark RI-MP2 database of nucleic acid base trimers: performance of different density functional models for prediction of structures and binding energies.
Martin Kabelác (2007)
Anal
L. M. Demers (2000)
10.1016/j.jbiotec.2005.02.019
Colorimetric detection of eukaryotic gene expression with DNA-derivatized gold nanoparticles.
Pedro Viana Baptista (2005)
10.1021/ja034876s
Rapid aggregation of gold nanoparticles induced by non-cross-linking DNA hybridization.
Ken Sato (2003)
10.1373/clinchem.2005.065391
Gold-nanoparticle-probe-based assay for rapid and direct detection of Mycobacterium tuberculosis DNA in clinical samples.
Pedro Viana Baptista (2006)
Chem
A.K.R. Lytton-Jean (2005)
Curr
M. M. Cheng (2006)
Chem
K. A. Brown (2008)
10.1038/382607a0
A DNA-based method for rationally assembling nanoparticles into macroscopic materials
Chad A. Mirkin (1996)
10.1021/JP711869P
Nucleotide−Surface Interactions in DNA-Modified Au−Nanoparticle Conjugates: Sequence Effects on Reactivity and Hybridization
Kate Brown (2008)
10.1021/ac0613582
Maximizing DNA loading on a range of gold nanoparticle sizes.
Sarah J. Hurst (2006)
10.1021/ja021096v
What controls the melting properties of DNA-linked gold nanoparticle assemblies?
R. Jin (2000)
Chem
R. Jin (2003)
10.1016/j.cbpa.2006.01.006
Nanotechnologies for biomolecular detection and medical diagnostics.
Mark Ming-Cheng Cheng (2006)
10.1049/iet-nbt:20070001
Nanodiagnostics: fast colorimetric method for single nucleotide polymorphism/mutation detection.
Gonçalo Doria (2007)
10.1039/B614420A
Hydration and stability of nucleic acid bases and base pairs.
Martin Kabelác (2007)
119 (2005) 111
P. Baptista (2007)
10.1021/ja052255o
A thermodynamic investigation into the binding properties of DNA functionalized gold nanoparticle probes and molecular fluorophore probes.
Abigail K. R. Lytton-Jean (2005)
10.1021/ja052352h
Thermodynamics of DNA hybridization on gold nanoparticles.
Jun Xu (2005)
Anal
P. Baptista (2008)
10.1021/j100214a025
Adsorption and surface-enhanced Raman of dyes on silver and gold sols
Plato C. Lee (1982)
10.1021/ac034256+
Oligonucleotide-functionalized gold nanoparticles as probes in a dry-reagent strip biosensor for DNA analysis by hybridization.
Kyriaki Glynou (2003)
10.1007/S00216-007-1768-Z
Gold nanoparticles for the development of clinical diagnosis methods
Pedro Viana Baptista (2008)
10.1021/ac0006627
A fluorescence-based method for determining the surface coverage and hybridization efficiency of thiol-capped oligonucleotides bound to gold thin films and nanoparticles.
Linette M Demers (2000)



This paper is referenced by
10.1039/c4cc07184k
Gold nanoprobes for detecting DNA adducts.
Ioannis A. Trantakis (2014)
Gold nanoparticles for nanotheranostics in leukemia – Addressing Chronic Myeloid Leukemia
Raquel Vinhas (2018)
10.1586/14737159.2015.1077704
Gold nanoprobe-based non-crosslinking hybridization for molecular diagnostics
Miguel Larguinho (2015)
10.1039/C1RA00206F
The electrogenerated chemiluminescence detection of IS6110 of Mycobacterium tuberculosis based on a luminol functionalized gold nanoprobe
Jie Jiang (2011)
10.1007/978-1-61779-953-2_6
RNA quantification using noble metal nanoprobes: simultaneous identification of several different mRNA targets using color multiplexing and application to cancer diagnostics.
João Conde (2012)
10.1088/0957-4484/21/41/415101
Au-nanoprobes for detection of SNPs associated with antibiotic resistance in Mycobacterium tuberculosis.
Bruno Veigas (2010)
10.1016/j.colsurfb.2011.12.026
Aggregation effects of gold nanoparticles for single-base mismatch detection in influenza A (H1N1) DNA sequences using fluorescence and Raman measurements.
Erdene-Ochir Ganbold (2012)
10.1016/J.SMALLRUMRES.2016.11.021
Colorimetric detection of caprine arthritis encephalitis virus (CAEV) through loop-mediated isothermal amplification (LAMP) with gold nanoprobes
Michelle M. Balbin (2017)
10.1007/978-1-4939-2172-0_3
Mobile based gold nanoprobe TB diagnostics for point-of-need.
Bruno Veigas (2015)
10.1016/j.ab.2014.07.019
Characterization of genomic single nucleotide polymorphism via colorimetric detection using a single gold nanoprobe.
Fábio Ferreira Carlos (2014)
10.1016/j.bios.2016.11.001
Gold aggregating gold: A novel nanoparticle biosensor approach for the direct quantification of hepatitis C virus RNA in clinical samples
Sherif M. Shawky (2017)
10.1016/J.SNB.2015.03.052
The efficiency analysis of gold nanoprobes by FT-IR spectroscopy applied to the non-cross-linking colorimetric detection of Paracoccidioides brasiliensis
Maiara L. Castilho (2015)
10.1088/0957-4484/21/50/505101
In vitro transcription and translation inhibition via DNA functionalized gold nanoparticles.
João P. Conde (2010)
10.1016/J.PHYSE.2015.09.018
Colorimetric DNA detection of transgenic plants using gold nanoparticles functionalized with L-shaped DNA probes
Elham Nourisaeid (2016)
10.1016/J.JELECHEM.2017.03.001
Impedimetric biosensor modified with hydrophilic material of tannic acid/polyethylene glycol and dopamine-assisted deposition for detection of breast cancer-related BRCA1 gene
Lihua Chen (2017)
Cancer theranostics: multifunctional gold nanoparticles for diagnostics and therapy
João Conde (2013)
10.1002/bit.25542
Single nucleotide polymorphism detection using gold nanoprobes and bio-microfluidic platform with embedded microlenses.
Iwona Bernacka-Wojcik (2015)
10.1007/978-1-0716-0319-2_19
RNA Quantification Using Noble Metal Nanoprobes: Simultaneous Identification of Several Different mRNA Targets Using Color Multiplexing and Application to Chronic Myeloid Leukemia Diagnostics.
Pedro Viana Baptista (2020)
10.1016/j.jprot.2011.11.007
Gold and silver nanoparticles for clinical diagnostics - From genomics to proteomics.
Miguel Larguinho (2012)
Gold nanoparticles for the detection of DNA adducts as biomarkers of exposure to acrylamide
Miguel Larguinho (2014)
10.1016/B978-0-12-416020-0.00011-5
Nanoparticles in molecular diagnostics.
Pedro Viana Baptista (2011)
High throughput detection of telomerase expression by gold nanoprobes assay (nano- TRAP assay): An alternative method to conventional method of telomerase detection
Abbas Ebrahimi-Kalan (2015)
Characterization of genomic SNP via colorimetric detection using a single gold nanoprobe
Fábio Ferreira Carlos (2014)
10.1007/s11051-012-1321-7
Controlled adsorption of cytochrome c to nanostructured gold surfaces
Inês Gomes (2012)
mRNA genotyping by gold nanoprobes
Maria Saraiva Mendes Assunção (2011)
10.1109/TNB.2014.2365256
Gold Nanoprobe-Based Detection of Human Telomerase Reverse Transcriptase (hTERT) Gene Expression
Mohammad Pourhassan-Moghaddam (2015)
10.1039/c4an00810c
Localized surface plasmon resonance (LSPR) biosensing using gold nanotriangles: detection of DNA hybridization events at room temperature.
Leonor A. S Soares (2014)
10.1016/j.bbrc.2018.01.033
Gold nanoparticle-based probes for the colorimetric detection of Mycobacterium avium subspecies paratuberculosis DNA.
Thenor Aristotile Charles S Ganareal (2018)
10.1016/j.bios.2010.08.078
Portable optoelectronic biosensing platform for identification of mycobacteria from the Mycobacterium tuberculosis complex.
Leonardo Bione Silva (2011)
10.1016/j.aca.2010.07.046
Development and characterization of a magnetic bead-quantum dot nanoparticles based assay capable of Escherichia coli O157:H7 quantification.
Gha-Young Kim (2010)
Semantic Scholar Logo Some data provided by SemanticScholar