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Routes Of Transmission During A Nosocomial Influenza A(H3N2) Outbreak Among Geriatric Patients And Healthcare Workers.

D. Eibach, J. Casalegno, M. Bouscambert, T. Bénet, C. Régis, B. Comte, B-A Kim, P. Vanhems, B. Lina
Published 2014 · Medicine

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BACKGROUND Influenza presents a life-threatening infection for hospitalized geriatric patients, who might be nosocomially infected via healthcare workers (HCWs), other patients or visitors. In the 2011/2012 influenza season an influenza A(H3N2) outbreak occurred in the geriatric department at the Hôpital Edouard Herriot, Lyon. AIM To clarify the transmission chain for this influenza A(H3N2) outbreak by sequence analysis and to identify preventive measures. METHODS Laboratory testing of patients with influenza-like illness in the acute care geriatric department revealed 22 cases of influenza between 19th February and 15th March 2012. Incidences for patients and HCWs were calculated and possible epidemiological links were analysed using a questionnaire. Neuraminidase and haemagglutinin genes of culture-positive samples and community influenza samples were sequenced and clustered to detect patients with identical viral strains. FINDINGS Sixteen patients and six HCWs were affected, resulting in an attack rate of 24% and 11% respectively. Six nosocomial infections were recorded. The sequence analysis confirmed three independent influenza clusters on three different sections of the geriatric ward. For at least two clusters, an HCW source was determined. CONCLUSION Epidemiological and microbiological results confirm influenza transmission from HCWs to patients. A higher vaccination rate, isolation measures and better hand hygiene are recommended in order to prevent outbreaks in future influenza seasons.
This paper references
[Vaccination against influenza: results of a study on vaccination coverage among health care workers in the Croix-Rousse Hospital (Hospitals of Lyon)].
F. Valour (2007)
10.1186/1471-2288-11-53
A multiplicative hazard regression model to assess the risk of disease transmission at hospital during community epidemics
N. Voirin (2011)
10.1016/j.jhin.2012.08.004
Sequence-based identification and characterization of nosocomial influenza A(H1N1)pdm09 virus infections.
M. Jonges (2012)
10.1016/S1473-3099(02)00221-9
Influenza in the acute hospital setting.
C. Salgado (2002)
10.1186/1741-7015-9-87
Simulation of an SEIR infectious disease model on the dynamic contact network of conference attendees
Juliette Stehlé (2011)
10.1086/656743
Possible Role of Aerosol Transmission in a Hospital Outbreak of Influenza
B. Wong (2010)
Vaccines against influenza WHO position paper – November 2012.
(2012)
10.1016/S0755-4982(06)74830-8
Épidémie de grippe nosocomiale dans un service de gériatrie: Efficacité des mesures de prévention
Anne-Gaëlle Andrieu (2006)
10.2807/ESE.18.05.20389-EN
Vaccine effectiveness of 2011/12 trivalent seasonal influenza vaccine in preventing laboratory-confirmed influenza in primary care in the United Kingdom: evidence of waning intra-seasonal protection.
R. Pebody (2013)
10.1016/j.vaccine.2008.01.051
Influenza-related hospitalisation and death in Australians aged 50 years and older
A. Newall (2008)
enotyping of a nosocomial outbreak of pandemic influenza A / H 1 N 1 2009
. Rodríguez-Sáncheza (2011)
10.1016/J.MEDMAL.2006.10.007
Vaccination contre la grippe: résultats d'une enquête sur la couverture vaccinale du personnel hospitalier à l'hôpital de la Croix-Rousse (hôpitaux de Lyon)
F. Valour (2007)
10.1086/501981
Disruption of Services in an Internal Medicine Unit Due to a Nosocomial Influenza Outbreak
C. Sartor (2002)
10.1001/ARCHINTE.161.10.1351
Clinical signs and symptoms predicting influenza infection.
E. Hak (2001)
10.1017/S0950268812000659
High morbidity and mortality associated with an outbreak of influenza A(H3N2) in a psycho-geriatric facility
G. Sayers (2012)
10.1093/molbev/msr121
MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods.
K. Tamura (2011)
10.1186/1471-2334-12-30
Influenza vaccination of healthcare workers in acute-care hospitals: a case-control study of its effect on hospital-acquired influenza among patients
T. Bénet (2012)
10.1016/j.jcv.2011.07.001
Genotyping of a nosocomial outbreak of pandemic influenza A/H1N1 2009.
B. Rodríguez-Sánchez (2011)
10.1001/archinternmed.2010.500
Risk of influenza-like illness in an acute health care setting during community influenza epidemics in 2004-2005, 2005-2006, and 2006-2007: a prospective study.
P. Vanhems (2011)
10.1016/S0755-4982(06)74830-8
[Nosocomial influenza outbreak in a geriatrics department: Effectiveness of preventive measures].
Anne-Gaëlle Andrieu (2006)
10.1097/QCO.0b013e3283013945
Nosocomial influenza: new concepts and practice
H. Maltezou (2008)
10.1371/journal.pone.0011596
Dynamics of Person-to-Person Interactions from Distributed RFID Sensor Networks
C. Cattuto (2010)
10.1086/658671
Molecular Characteristics of Outbreaks of Nosocomial Infection with Influenza A/H3N2 Virus Variants
Taeko Oguma (2011)
10.1371/journal.pone.0023176
High-Resolution Measurements of Face-to-Face Contact Patterns in a Primary School
Juliette Stehlé (2011)
10.1007/978-94-011-6630-0_6
Vaccines against influenza
C. Hannoun (1978)



This paper is referenced by
10.1016/j.jvacx.2019.100036
A rapid evidence appraisal of influenza vaccination in health workers: An important policy in an area of imperfect evidence
Dawn C. Jenkin (2019)
10.1080/21645515.2015.1082014
Vaccination of healthcare workers: A review
S. Haviari (2015)
10.1016/B978-0-323-35761-6.00072-9
72 – Vaccines for Healthcare Personnel
D. Weber (2018)
10.1017/ice.2015.67
Isolation Precautions for Visitors
L. Munoz-Price (2015)
10.1201/9781315226255-51
The Impact of Patient Room Design on Airborne Hospital-Acquired Infections (HAI)
Alexa Copeland (2017)
The pandemic potential of avian in fl uenza A ( H 7 N 9 ) virus : a review
W. Tanner (2015)
10.1016/j.ajic.2018.10.024
Nosocomial outbreak of influenza A H3N2 in an inpatient oncology unit related to health care workers presenting to work while ill
Kerry Wilson (2019)
10.1016/j.vaccine.2017.12.019
How close are countries of the WHO European Region to achieving the goal of vaccinating 75% of key risk groups against influenza? Results from national surveys on seasonal influenza vaccination programmes, 2008/2009 to 2014/2015
P. Jørgensen (2018)
10.1111/irv.12750
Are healthcare workers more likely than the general population to consult in primary care for an influenza‐like illness? Results from a case‐control study
A. Peytremann (2020)
10.1093/eurpub/ckw031
Influenza in workplaces: transmission, workers’ adherence to sick leave advice and European sick leave recommendations
Christina Hansen Edwards (2016)
10.1016/j.ajic.2019.06.020
Intermittent occurrence of health care-onset influenza cases in a tertiary care facility during the 2017-2018 flu season.
W. Bischoff (2019)
10.28971/532018cw163
The Impact of Rhode Island's Mandatory Health Care Worker Influenza Vaccination Regulation on Influenza Incidence in Long-Term Care Facility Residents
Wendy A. Chicoine (2018)
10.1016/S1473-3099(14)70831-X
Emerging viral respiratory tract infections—environmental risk factors and transmission
P. Gautret (2014)
Knowledge, perception and coverage rates regarding influenza vaccination among nursing Staff
Izabela Gołębiak (2016)
10.1093/occmed/kqv155
Practical prevention of nosocomial influenza transmission, 'a hierarchical control' issue.
Frank O'Reilly (2015)
10.1111/ijn.12512
Intention to receive the seasonal influenza vaccine among nurses working in a long‐term care facility
Irit Shahar (2017)
10.1080/21645515.2020.1801072
Monitoring influenza vaccination coverage and acceptance among health-care workers in German hospitals – results from three seasons
J. Neufeind (2020)
10.1086/677167
Toward a Standardized Definition of Healthcare-Associated Influenza?
P. Vanhems (2014)
10.1007/s10096-014-2119-6
Healthcare workers as vectors of infectious diseases
R. Huttunen (2014)
10.9778/CMAJO.20160018
Influenza immunization among Canadian health care personnel: a cross-sectional study.
S. Buchan (2016)
10.1016/j.jhin.2014.12.017
Rapid bedside tests for diagnosis, management, and prevention of nosocomial influenza.
M. Bouscambert (2015)
10.1093/cid/ciy874
Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenzaa.
T. Uyeki (2019)
10.1111/IRV.12553
Influenza-like illness in healthcare personnel at a paediatric referral hospital: Clinical picture and impact of the disease.
Almudena Laris González (2018)
10.1016/J.IDH.2018.03.003
Attitudes of healthcare workers to influenza vaccination
Philippa Knowler (2018)
10.1097/MOP.0000000000000527
Mandatory influenza vaccination for all healthcare personnel: a review on justification, implementation and effectiveness
T. Wang (2017)
10.1016/j.jhin.2016.06.004
Management of an influenza A outbreak on an acute internal medicine ward.
N. Mahida (2016)
10.1111/jgs.13339
Transmission and Effect of Multiple Clusters of Seasonal Influenza in a Swiss Geriatric Hospital
L. Pagani (2015)
10.1017/S0950268815001570
The pandemic potential of avian influenza A(H7N9) virus: a review
W. Tanner (2015)
10.1111/irv.12679
Nosocomial transmission of influenza: A retrospective cross‐sectional study using next generation sequencing at a hospital in England (2012‐2014)
R. Blackburn (2019)
10.1039/C9NA00103D
Rechargeable polyamide-based N-halamine nanofibrous membranes for renewable, high-efficiency, and antibacterial respirators
R. Wang (2019)
10.1097/QCO.0000000000000287
Nosocomial influenza: encouraging insights and future challenges
P. Vanhems (2016)
10.1016/j.jhin.2015.04.019
Oseltamivir in influenza outbreaks in care homes: challenges and benefits of use in the real world.
S. Millership (2015)
See more
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