Online citations, reference lists, and bibliographies.
Please confirm you are human
(Sign Up for free to never see this)
← Back to Search

Neuromagnetic Detection Of The Laryngeal Area: Sensory-evoked Fields To Air-puff Stimulation

Hideaki Miyaji, N. Hironaga, T. Umezaki, K. Hagiwara, H. Shigeto, M. Sawatsubashi, S. Tobimatsu, S. Komune
Published 2014 · Psychology, Computer Science, Medicine

Save to my Library
Download PDF
Analyze on Scholarcy
Share
The sensory projections from the oral cavity, pharynx, and larynx are crucial in assuring safe deglutition, coughing, breathing, and voice production/speaking. Although several studies using neuroimaging techniques have demonstrated cortical activation related to pharyngeal and laryngeal functions, little is known regarding sensory projections from the laryngeal area to the somatosensory cortex. The purpose of this study was to establish the cortical activity evoked by somatic air-puff stimulation at the laryngeal mucosa using magnetoencephalography. Twelve healthy volunteers were trained to inhibit swallowing in response to air stimuli delivered to the larynx. Minimum norm estimates was performed on the laryngeal somatosensory evoked fields (LSEFs) to best differentiate the target activations from non-task-related activations. Evoked magnetic fields were recorded with acceptable reproducibility in the left hemisphere, with a peak latency of approximately 100ms in 10 subjects. Peak activation was estimated at the caudolateral region of the primary somatosensory area (S1). These results establish the ability to detect LSEFs with an acceptable reproducibility within a single subject and among subjects. These results also suggest the existence of laryngeal somatic afferent input to the caudolateral region of S1 in human. Our findings indicate that further investigation in this area is needed, and should focus on laryngeal lateralization, swallowing, and speech processing.
This paper references
10.3389/fphys.2010.00167
Cortical Gating of Oropharyngeal Sensory Stimuli
K. Wheeler-Hegland (2011)
10.1002/hbm.20488
Time‐dependent hemispheric shift of the cortical control of volitional swallowing
I. Teismann (2009)
10.1016/j.neuroimage.2008.06.040
Oral structure representation in human somatosensory cortex
Y. Tamura (2008)
Functional neuroimaging by Synthetic Aperture Magnetometry (SAM)
Se Robinson (1999)
10.1007/BF02512476
Interpreting magnetic fields of the brain: minimum norm estimates
M. Hämäläinen (2006)
lent laryngopharyngeal sensory de fi cits after stroke
J. E. Aviv
10.1523/JNEUROSCI.4897-09.2009
Functional But Not Structural Networks of the Human Laryngeal Motor Cortex Show Left Hemispheric Lateralization during Syllable But Not Breathing Production
K. Simonyan (2009)
10.1006/METH.2001.1238
Signal processing in magnetoencephalography.
J. Vrba (2001)
10.1016/S0006-8993(02)02960-8
Cortico-cortical projections of the motorcortical larynx area in the rhesus monkey
K. Simonyan (2002)
10.3171/JNS-07/09/0481
Predicting the location of mouth motor cortex in patients with brain tumors by using somatosensory evoked field measurements.
H. Kirsch (2007)
10.1016/j.neuroimage.2004.11.051
Localization bias and spatial resolution of adaptive and non-adaptive spatial filters for MEG source reconstruction
K. Sekihara (2005)
10.1002/CNE.901930210
Brain stem projections of sensory and motor components of the vagus complex in the cat: I. The cervical vagus and nodose ganglion
M. Kalia (1980)
10.1016/0003-9993(93)90082-L
Swallowing after unilateral stroke of the cerebral cortex.
J. Robbins (1993)
10.1162/jocn.1993.5.2.162
Improved Localizadon of Cortical Activity by Combining EEG and MEG with MRI Cortical Surface Reconstruction: A Linear Approach
A. Dale (1993)
10.1016/j.clinph.2004.05.017
Characterising the central mechanisms of sensory modulation in human swallowing motor cortex
D. Gow (2004)
10.1177/000348949810700503
FEESST: A New Bedside Endoscopic Test of the Motor and Sensory Components of Swallowing
Ted H. Kim (1998)
Lateralization of cortical function in swallowing: a functional MR imaging study.
K. Mosier (1999)
10.1093/BRAIN/60.4.389
SOMATIC MOTOR AND SENSORY REPRESENTATION IN THE CEREBRAL CORTEX OF MAN AS STUDIED BY ELECTRICAL STIMULATION
W. Penfield (1937)
10.1002/cne.10935
Ipsilateral representation of oral structures in human anterior parietal somatosensory cortex and integration of inputs across the midline
E. Disbrow (2003)
10.1016/0006-8993(90)91390-3
Central projections of coarse and fine vagal axons of the cat
F. Torrealba (1990)
10.1007/s00455-005-0021-1
Oropharyngeal Stimulation with Air-Pulse Trains Increases Swallowing Frequency in Healthy Adults
J. Theurer (2005)
10.1007/s00221-008-1330-z
Interactions between auditory and somatosensory feedback for voice F0 control
C. Larson (2008)
10.1016/j.neuroimage.2008.04.234
Sensory stimulation activates both motor and sensory components of the swallowing system
Soren Y. Lowell (2008)
10.1177/000348949610500202
Supraglottic and Pharyngeal Sensory Abnormalities in Stroke Patients with Dysphagia
J. H. Martin (1996)
10.1016/0361-9230(95)00018-6
Convergence of afferents from the SLN and GPN in cat medullary swallowing neurons
Shinji Ootani (1995)
10.1093/cercor/bhq023
Abnormal activation of the primary somatosensory cortex in spasmodic dysphonia: an fMRI study.
K. Simonyan (2010)
Dynamic Statistical Parametric Neurotechnique Mapping: Combining fMRI and MEG for High-Resolution Imaging of Cortical Activity
A. Dale (2000)
10.1006/nimg.1998.0396
Cortical Surface-Based Analysis: II: Inflation, Flattening, and a Surface-Based Coordinate System
B. Fischl (1999)
10.1016/0361-9230(93)90231-Y
Origin of laryngeal sensory-evoked potentials (LSEPs) in the cat
Tsuyako Fukuyama (1993)
10.1023/B:BRAT.0000032864.93890.f9
Suppression of Interference and Artifacts by the Signal Space Separation Method
S. Taulu (2005)
10.1006/nimg.1998.0395
Cortical Surface-Based Analysis: I. Segmentation and Surface Reconstruction
A. Dale (1999)
NeuroImage
H Miyaji (2014)
10.1016/0013-4694(96)95154-8
Movement-related slow cortical magnetic fields and changes of spontaneous MEG- and EEG-brain rhythms.
T. Nagamine (1996)
10.1113/jphysiol.2003.057885
Identification of the tracheal and laryngeal afferent neurones mediating cough in anaesthetized guinea‐pigs
B. Canning (2004)
10.1016/S0006-8993(03)02548-4
Efferent subcortical projections of the laryngeal motorcortex in the rhesus monkey
K. Simonyan (2003)
10.1186/1471-2202-10-76
Measurement of pharyngeal sensory cortical processing: technique and physiologic implications
I. Teismann (2008)
10.1097/00001756-199806010-00022
Medullary swallowing‐related neurons in the anesthetized cat
T. Umezaki (1998)
10.1016/S1052-3057(96)80018-8
Lesion site in unilateral stroke patients with dysphagia.
B. Jacobson (1996)
10.1177/000348949710600201
Silent Laryngopharyngeal Sensory Deficits after Stroke
R. Sacco (1997)
10.1097/00004728-199403000-00005
Automatic 3D Intersubject Registration of MR Volumetric Data in Standardized Talairach Space
D. L. Collins (1994)
10.1038/nature11911
Functional Organization of Human Sensorimotor Cortex for Speech Articulation
K. Bouchard (2013)
10.1016/j.neuroimage.2004.02.041
Dissociating the spatio-temporal characteristics of cortical neuronal activity associated with human volitional swallowing in the healthy adult brain
P. Furlong (2004)
10.1007/s00455-005-9007-2
Swallowing Lateralization: The Effects of Modified Dual-Task Interference
S. Daniels (2005)



This paper is referenced by
10.1016/j.neuroimage.2016.01.065
A spatiotemporal signature of cortical pain relief by tactile stimulation: An MEG study
Mariko Hayamizu (2016)
10.1093/cercor/bhw393
Functional and Quantitative MRI Mapping of Somatomotor Representations of Human Supralaryngeal Vocal Tract
D. Carey (2017)
10.1177/0003489416683192
Influence of External Subglottic Air Flow on Dysphagic Tracheotomized Patients With Severe Brain Injury
M. Kothari (2017)
10.1101/2020.02.20.958314
Mapping human laryngeal motor cortex during vocalization
Nicole Eichert (2020)
10.1038/s41598-020-67295-w
Altered sensory system activity and connectivity patterns in adductor spasmodic dysphonia
Tobias Mantel (2020)
10.1136/bmjopen-2016-015235
Accuracy and reliability of the sensory test performed using the laryngopharyngeal endoscopic esthesiometer and rangefinder in patients with suspected obstructive sleep apnoea hypopnoea: protocol for a prospective double-blinded, randomised, exploratory study
L. Giraldo-Cadavid (2017)
10.1002/lary.28284
Laryngeal afferent modulation of swallowing interneurons in the dorsal medulla in perfused rats
S. Fuse (2019)
10.1080/08990220.2020.1784127
Secondary somatosensory area is involved in vibrotactile temporal-structure processing: MEG analysis of slow cortical potential shifts in humans
K. Hagiwara (2020)
10.1186/s12938-016-0166-1
Design, development and validation of a new laryngo-pharyngeal endoscopic esthesiometer and range-finder based on the assessment of air-pulse variability determinants
L. F. Giraldo-Cadavid (2016)
10.1016/j.neubiorev.2017.03.014
The origins of the vocal brain in humans
Michel Belyk (2017)
10.1101/2020.07.21.213868
Motor and Sensory Cortical Processing of Neural Oscillatory Activities revealed by Human Swallowing using Intracranial Electrodes
Hiroaki Hashimoto (2020)
10.1093/cercor/bhaa182
Mapping Human Laryngeal Motor Cortex during Vocalization.
Nicole Eichert (2020)
10.1016/j.neures.2016.02.004
Neuromagnetic evidence that the right fusiform face area is essential for human face awareness: An intermittent binocular rivalry study
Yuko Kume (2016)
10.1101/2020.12.05.412783
Swallowing-related neural oscillation: An intracranial EEG study
Hiroaki Hashimoto (2020)
Semantic Scholar Logo Some data provided by SemanticScholar