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Occurrence, Interactive Effects And Ecological Risk Of Diclofenac In Environmental Compartments And Biota - A Review.
P. Sathishkumar, R. Meena, T. Palanisami, V. Ashokkumar, T. Palvannan, F. Gu
Published 2020 · Medicine, Environmental Science
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Time to take this seriously.
Diclofenac, a nonsteroidal anti-inflammatory drug has turned into a contaminant of emerging concern; hence, it was included in the previous Watch List of the EU Water Framework Directive. This review paper aims to highlight the metabolism of diclofenac at different trophic levels, its occurrence, ecological risks, and interactive effects in the water cycle and biota over the past two decades. Increased exposure to diclofenac not only raises health concerns for vultures, aquatic organisms, and higher plants but also causes serious threats to mammals. The ubiquitous nature of diclofenac in surface water (river, lake canal, estuary, and sea) is compared with drinking water, groundwater, and wastewater effluent in the environment. This comprehensive survey from previous studies suggests the fate of diclofenac in wastewater treatment plants (WWTPs) and may predict its persistence in the environment. This review offers evidence of fragmentary available data for the water environment, soil, sediment, and biota worldwide and supports the need for further data to address the risks associated with the presence of diclofenac in the environment. Finally, we suggest that the presence of diclofenac and its metabolites in the environment may represent a high risk because of their synergistic interactions with existing contaminants, leading to the development of drug-resistant strains and the formation of newly emerging pollutants.
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A Critical Review of Morphologic Findings and Data From 14 Toxicological Studies Involving Fish Exposures to Diclofenac
J. Wolf (2021)
Effects of diclofenac on sentinel species and aquatic communities in semi-natural conditions.
S. Joachim (2021)
Adsorption of diclofenac sodium by composite beads prepared from tannery wastes-derived gelatin and carbon nanotubes
Cesar Vinicus Toniciolli Rigueto (2021)
Assessing the bioremediation potential of indigenously isolated Klebsiella sp. WAH1 for diclofenac sodium: optimization, toxicity and metabolic pathway studies
Saloni Sharma (2021)
Development and Characterization of Composite Carbon Adsorbents with Photocatalytic Regeneration Ability: Application to Diclofenac Removal from Water
Velma Beri Kimbi Yaah (2021)
Exposure of Mytilus trossulus to diclofenac and 4'-hydroxydiclofenac: Uptake, bioconcentration and mass balance for the evaluation of their environmental fate.
K. Świacka (2021)
Modified oil palm industry solid waste as a potential adsorbent for lead removal
M. A. Elias (2021)
Impact of Pharmaceuticals and Their Metabolites on Environment
A. Sen (2021)
Emerging contaminants adsorption by beads from chromium (III) tanned leather waste recovered gelatin
Cesar Vinicus Toniciolli Rigueto (2021)
Does diclofenac act like a photosynthetic herbicide on green algae? Chlamydomonas reinhardtii synchronous culture-based study with atrazine as reference.
M. Majewska (2021)
Pharmaceutical compound removal efficiency by a small constructed wetland located in south Brazil
Jocelina Paranhos Rosa De Vargas (2021)
Photocatalytic degradation of diclofenac using TiO2-CdS heterojunction catalysts under visible light irradiation
Mugunthan Elangovan (2021)
Presence and Reduction of Anthropogenic Substances with UV Light and Oxidizing Disinfectants in Wastewater—A Case Study at Kuopio, Finland
Jenni Ikonen (2021)
The antineoplastic drugs cyclophosphamide and cisplatin in the aquatic environment - Review.
Vanessa Queirós (2021)
Anti-inflammatory drugs in the Vistula River following the failure of the Warsaw sewage collection system in 2019.
P. Stepnowski (2020)
Photocatalytic-persulfate- oxidation for diclofenac removal from aqueous solutions: Modeling, optimization and biotoxicity test assessment.
Anfel Smaali (2020)
Environmental risk assessment of the anthelmintic albendazole in Eastern Africa, based on a systematic review.
S. Belew (2020)
Occurrence and ecological risk assessment of pharmaceuticals and cocaine in a beach area of Guarujá, São Paulo State, Brazil, under the influence of urban surface runoff
Vinicius Roveri (2020)See more