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Carbon Dots For Multiphoton Bioimaging.

L. Cao, X. Wang, M. Meziani, Fushen Lu, Haifang Wang, P. Luo, Yi Lin, Barbara A. Harruff, L. Veca, Davoy Murray, S. Xie, Ya-Ping Sun
Published 2007 · Chemistry, Medicine

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Carbon nanoparticles upon simple surface passivation exhibit bright photoluminescence. Reported here is a new finding that these carbon dots are also strongly two-photon luminescent with pulsed laser excitation in the near-infrared. The experimentally measured two-photon absorption cross-sections are comparable to those of the high-performance semiconductor quantum dots already available in the literature. The two-photon luminescence microscopy imaging of human breast cancer cells with internalized carbon dots is demonstrated.

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