← Back to Search
Temperature-responsive Self-assembled Monolayers Of Oligo(ethylene Glycol): Control Of Biomolecular Recognition.
H. Zareie, C. Boyer, V. Bulmus, Ebrahim Nateghi, T. Davis
Published 2008 · Materials Science, Medicine
Download PDFAnalyze on Scholarcy
Self-assembled monolayers (SAMs) of oligo(ethylene glycol) (OEG)-tethered molecules on gold are important for various biorelevant applications ranging from biomaterials to bioanalytical devices, where surface resistance to nonspecific protein adsorption is needed. Incorporation of a stimuli-responsive character to the OEG SAMs enables the creation of nonfouling surfaces with switchable functionality. Here we present an OEG-derived structure that is highly responsive to temperature changes in the vicinity of the physiological temperature, 37 degrees C. The temperature-responsive solution behavior of this new compound was demonstrated by UV-vis and nuclear magnetic resonance spectroscopy. Its chemisorption onto gold(111), and the retention of responsive behavior after chemisorption have been demonstrated by surface plasmon resonance (SPR), X-ray photoelectron spectroscopy (XPS), and atomic force and scanning tunneling microscopy. The OEG-derived SAMs have been shown to reversibly switch the wettability of the surface, as determined by contact angle measurements. More importantly, SPR and AFM studies showed that the OEG SAMs can be utilized to control the affinity binding of streptavidin to the biotin-tethered surface in a temperature-dependent manner while still offering the nonspecific protein-resistance to the surface.
This paper references
Influence of End Groups on Phase Behavior and Properties of PEO in Aqueous Solutions
Elena E Dormidontova (2004)
Thermal Response of Poly(N-isopropylacrylamide) Brushes Probed by Surface Plasmon Resonance.
S. Balamurugan (2003)
Factors that determine the protein resistance of oligoether self-assembled monolayers --internal hydrophilicity, terminal hydrophilicity, and lateral packing density.
S. Herrwerth (2003)
Controlling Cell Adhesion to Titanium: Functionalization of Poly[oligo(ethylene glycol)methacrylate] Brushes with Cell‐Adhesive Peptides
J. E. Raynor (2007)
Thermosensitive gold nanoparticles.
Ming-Qiang Zhu (2004)
Nitrilotriacetic Acid Functionalized Graft Copolymers: A Polymeric Interface for Selective and Reversible Binding of Histidine-Tagged Proteins†
Guoliang Zhen (2006)
Temperature dependent activity and structure of adsorbed proteins on plasma polymerized N-isopropyl acrylamide
Xuanhong Cheng (2006)
Building layer-by-layer a bis(dithiocarbamato)copper(II) complex on Au surfaces.
R. Cao (2007)
Size sorting of protein assemblies using polymeric gradient surfaces.
L. Ionov (2005)
Chemisorbed poly(propylene sulphide)-based copolymers resist biomolecular interactions
J. Bearinger (2003)
Thermoresponsive behavior of poly(n-isopropylacrylamide) hydrogels containing gold nanostructures.
Frances Pong (2006)
Surface Characterization of Mixed Self-Assembled Monolayers Designed for Streptavidin Immobilization
K. Nelson (2001)
Soft lithography in biology and biochemistry.
G. Whitesides (2001)
Formation and Structure of Self-Assembled Monolayers.
A. Ulman (1996)
Thermosensitive water-soluble copolymers with doubly responsive reversibly interacting entities
I. Dimitrov (2007)
Point by point comparison of two thermosensitive polymers exhibiting a similar LCST: is the age of poly(NIPAM) over?
J. Lutz (2006)
A Novel Approach to Produce Protein Nanopatterns by Combining Nanoimprint Lithography and Molecular Self-Assembly
D. Falconnet (2004)
The interaction of oligo(ethylene oxide) with water: a quantum mechanical study
R. Wang (2000)
Poly(l-lysine)-g-poly(ethylene glycol) Layers on Metal Oxide Surfaces: Surface-Analytical Characterization and Resistance to Serum and Fibrinogen Adsorption
Ning-Ping Huang (2001)
Reversible protein adsorption and bioadhesion on monolayers terminated with mixtures of oligo(ethylene glycol) and methyl groups.
S. Balamurugan (2005)
Self-assembled organic monolayers: model systems for studying adsorption of proteins at surfaces
K. L. Prime (1991)
A Combined Photolithographic and Molecular‐Assembly Approach to Produce Functional Micropatterns for Applications in the Biosciences
Didier Falconnet (2004)
Extremely high thermal stability of streptavidin and avidin upon biotin binding.
M. González (1999)
Poly(l-lysine)-graft-poly(ethylene glycol) Assembled Monolayers on Niobium Oxide Surfaces: A Quantitative Study of the Influence of Polymer Interfacial Architecture on Resistance to Protein Adsorption by ToF-SIMS and in Situ OWLS
S. Pasche (2003)
Adsorption and thermoresponsive behavior of poly(N-isopropylacrylamide-co-N,N'-cystaminebisacrylamide) thin films on gold.
Ellane J. Park (2007)
Adsorption of proteins onto surfaces containing end-attached oligo(ethylene oxide): a model system using self-assembled monolayers
K. Prime (1993)
Pre-Adsorption of Amphiphilic Polymers on Synthetic Surfaces for Biofouling Retardation
X. Chen (2006)
High resolution XPS of organic polymers The Scienta ESCA300 Database
J. Comyn (1993)
Self-assembled monolayers of thiolates on metals as a form of nanotechnology.
J. Love (2005)
Stable antifouling surfaces
R. Nuzzo (2003)
Roles of enthalpy, entropy, and hydrogen bonding in the lower critical solution temperature behavior of poly(ethylene oxide)/water solutions
G. Smith (2003)
Reversible active switching of the mechanical properties of a peptide film at a fluid–fluid interface
Annette F. Dexter (2006)
Responsive materials: soft answers for hard problems.
P. Mather (2007)
Thermoresponsive Surface-Grafted Poly(N−isopropylacrylamide) Copolymers: Effect of Phase Transitions on Protein and Bacterial Attachment
D. Cunliffe (2003)
Biotin-Derivatized Poly(L-lysine)-g-poly(ethylene glycol): A Novel Polymeric Interface for Bioaffinity Sensing
Ning-Ping Huang (2002)
Immobilization of oriented protein molecules on poly(ethylene glycol)‐coated Si(111)
Taewoon Cha (2004)
Binding and Dissociation Kinetics of Wild-Type and Mutant Streptavidins on Mixed Biotin-Containing Alkylthiolate Monolayers
Linda S. Jung (2000)
A streptavidin linker layer that functions after drying.
N. Xia (2004)
Grafting Nitrilotriacetic Groups onto Carboxylic Acid-Terminated Self-Assembled Monolayers on Gold Surfaces for Immobilization of Histidine-Tagged Proteins
J. Lee (2004)
Poly[(N-isopropylacrylamide-co-acrylamide-co-(hydroxyethylmethacrylate))] thermoresponsive microspheres: An accurate method based on solute exclusion technique to determine the volume phase transition temperature
G. Fundueanu (2007)
Temperature-induced large and reversible photonic bandgap switching in self-assembled polymeric solid films
Sami Valkama (2004)
MOLECULAR CONFORMATION AND SOLVATION OF OLIGO(ETHYLENE GLYCOL)-TERMINATED SELF-ASSEMBLED MONOLAYERS AND THEIR RESISTANCE TO PROTEIN ADSORPTION
R. Wang (1997)
Thermal and sodium dodecylsulfate induced transitions of streptavidin.
Mark J. Waner (2004)
Effect of comonomer hydrophilicity and ionization on the lower critical solution temperature of N-isopropylacrylamide copolymers
H. Feil (1993)
Molecular Recognition between Genetically Engineered Streptavidin and Surface-Bound Biotin
V. Pérez-Luna (1999)
Variable Adhesion of Micropatterned Thermoresponsive Polymer Brushes: AFM Investigations of Poly(N‐isopropylacrylamide) Brushes Prepared by Surface‐Initiated Polymerizations
Darren M. Jones (2002)
Synthesis of poly (N -isopropylacrylamide) copolymer containing anhydride and imide comonomers : A theoretical study on reversal of LCST
R. Francis (2007)
A new model for upper and lower critical solution temperatures in poly(ethylene oxide) solutions
G. Karlström (1985)
New deuterated oligo(ethylene glycol) building blocks and their use in the preparation of surface active lipids possessing labeled hydrophilic tethers.
Robert J. Faragher (2008)
High resolution XPS of organic polymers
G. Beamson (1992)
Aqueous dispersion, surface thiolation, and direct self-assembly of carbon nanotubes on gold.
N. Kocharova (2007)
Well-defined protein-polymer conjugates via in situ RAFT polymerization.
C. Boyer (2007)
Stable and functional immobilization of histidine-tagged proteins via multivalent chelator headgroups on a molecular poly(ethylene glycol) brush.
Suman Lata (2005)
Thermally responsive poly(N-isopropylacrylamide) monolayer on gold: synthesis, surface characterization, and protein interaction/adsorption studies
E. Cho (2004)
Sodium dodecyl sulfate‐polyacrylamide gel electrophoretic method for assessing the quaternary state and comparative thermostability of avidin and streptavidin
E. Bayer (1996)
Influence of a crown ether comonomer on the temperature-induced phase transition of poly(N-isopropylacrylamide) hydrogels.
K. Kosik (2008)
Direct Patterning of Protein‐ and Cell‐Resistant Polymeric Monolayers and Microstructures
A. Khademhosseini (2003)
Temperature Dependence of the Protein Resistance of Poly- and Oligo(ethylene glycol)-Terminated Alkanethiolate Monolayers
D. Schwendel (2001)
Long-Term Stability of Self-Assembled Monolayers in Biological Media
N. Flynn (2003)
Quantitative interpretation of the response of surface plasmon resonance sensors to adsorbed films
Linda S. Jung (1998)
XAS and XPS Characterization of Monolayers Derived from a Dithiol and Structurally Related Disulfide-Containing Polyamides
Andrew L. Vance (2002)
Immobilization of the enzyme beta-lactamase on biotin-derivatized poly(L-lysine)-g-poly(ethylene glycol)-coated sensor chips: a study on oriented attachment and surface activity by enzyme kinetics and in situ optical sensing.
Guoliang Zhen (2004)
Capture and release of proteins on the nanoscale by stimuli-responsive elastin-like polypeptide "switches".
J. Hyun (2004)
This paper is referenced by
Temperature-Switchable Control of Ligand Display on Adlayers of Mixed Poly(lysine)-g-(PEO) and Poly(lysine)-g-(ligand-modified poly-N-isopropylacrylamide).
Fabrice Dalier (2016)
Aptamer-Functionalized Field-Effect Transistors For Serotonin and Dopamine Sensing
Nako Nakatsuka (2017)
Kontrollierte Zelladhäsion auf PEG‐basierten schaltbaren Oberflächen
E. Wischerhoff (2008)
Ionic strength and pH-dependent conformation of mixed polymer brushes for cycles of protein adsorption and desorption
M. Delcroix (2013)
Surface modification, functionalization and bioconjugation of colloidal inorganic nanoparticles
R. A. Sperling (2010)
Synthesis and modification of thermoresponsive poly(oligo(ethylene glycol) methacrylate) via catalytic chain transfer polymerization and thiol–ene Michael addition
A. Soeriyadi (2011)
An In-Line Photonic Biosensor for Monitoring of Glucose Concentrations
Ala'aldeen Al-Halhouli (2014)
Tailoring multifunctional nanoparticles for encapsulation of bio-molecules.
K. Raghunathan (2017)
Thermoresponsive starch derivates with widely tuned LCSTs by introducing short oligo(ethylene glycol) spacers.
Benzhi Ju (2014)
RAFT polymerization and thiol chemistry: a complementary pairing for implementing modern macromolecular design.
P. Roth (2011)
Formation of cyclodextrin monolayer through a host–guest interaction with tailor-made phenyltriethoxysilane self-assembled monolayer
Yubiao Niu (2015)
Microfluidic Mass Production of Stabilized and Stealthy Liquid Metal Nanoparticles.
Shi-Yang Tang (2018)
Evaluation of multivalent, functional polymeric nanoparticles for imaging applications.
M. Shokeen (2011)
Self-Assembled Monolayers as Dynamic Model Substrates for Cell Biology
Abigail Pulsipher (2010)
Smart bioactive surfaces
Erik Wischerhoff (2010)
Protein conjugation of thermoresponsive amine-reactive polymers prepared by RAFT
Hongmei Li (2011)
Unusual effect of molecular weight and concentration on thermoresponsive behaviors of well‐defined water‐soluble semirigid polymers
Peng Liu (2012)
Vaginal Microbicide Films
José das Neves (2014)
Biomedical applications of nanodiamond (Review).
K. Turcheniuk (2017)
Patterned and switchable surfaces for biomolecular manipulation.
A. Hook (2009)
Unique Mixed Phases and Structures of Self-Assembled Monolayers on Au(111) Derived from Methoxy-terminated Mono(ethylene glycol)ethanethiols
Hungu Kang (2017)
Switchable surfaces for regulating biomolecular and cellular interactions under complex biological conditions
Minhaj Lashkor (2015)
Stable star polymer nanolayers and their thermoresponsiveness as a tool for controlled culture and detachment of fibroblast sheets.
Barbara Mendrek (2018)
Anti-fouling magnetic nanoparticles for siRNA delivery
C. Boyer (2010)
Photo selective protein immobilization using bovine serum albumin
Wan-Joong Kim (2012)
Temperature-Responsive Molecular Assemblies Using Oligo(Ethylene Glycol)-Attached Polyamidoamine Dendron Lipids and their Functions as Drug Carriers
Takuya Hashimoto (2020)
An electrically reversible switchable surface to control and study early bacterial adhesion dynamics in real-time.
Alice Pranzetti (2013)
A methodological combined framework for roadmapping biosensor research: a fault tree analysis approach within a strategic technology evaluation frame
Christina G. Siontorou (2014)
Engineering Proteins at Interfaces: From Complementary Characterization to Material Surfaces with Designed Functions
S. Morsbach (2018)
Bioinspired Surfaces with Superwettability: New Insight on Theory, Design, and Applications.
S. Wang (2015)
Synthesis and in vivo magnetic resonance imaging evaluation of biocompatible branched copolymer nanocontrast agents
A. W. Jackson (2015)
Antifouling property of monothiol-terminated bottle-brush poly(methylacrylic acid)-graft-poly(2-methyl-2-oxazoline) copolymer on gold surfaces.
Xiajun Zheng (2015)See more