← Back to Search
Nickel-catalyzed Highly Regioselective Multicomponent Coupling Of Ynamides, Aldehydes, And Silane: A New Access To Functionalized Enamides.
Nozomi Saito, T. Katayama, Yoshihiro Sato
Published 2008 · Chemistry, Medicine
Save to my Library
Download via 🐼 PaperPanda Download via oaDOI Download via OAB Download via LibKey Download via Google Google ScholarAnalyze on Scholarcy Visualize in Litmaps
Reduce the time it takes to create your bibliography by a factor of 10 by using the world’s favourite reference manager
Time to take this seriously.
A new method for preparation of functionalized enamides by a nickel-catalyzed multicomponent coupling of ynamides, aldehydes, and silane has been developed. The coupling reaction proceeded in the presence of a nickel-IMes catalyst to give the corresponding gamma-silyloxyenamide derivative, which has an allylic alcohol moiety in the molecule, in a highly stereoselective manner.
This paper is referenced by
Reactivity of ynamides with AlCl3 and ICl: Ready access to (E)-α-chloroenamides and (E/Z)-α-chloro-β-iodo-enamides
A. Siva Reddy (2021)
A Catalytic Construction of Indoles via Formation of Ruthenium Vinylidene Species from N ‐Arylynamides
Masanori Tayu (2021)
Nickel‐Catalyzed Three‐Component Coupling Reaction of Tetrafluoroethylene and Aldehydes with Silanes via Oxa‐Nickelacycles
Hiroshi Shirataki (2019)
Nickel-Catalyzed β-Carboxylation of Ynamides with Carbon Dioxide
Ryohei Doi (2019)
Nickel(0)-catalyzed Coupling Reactions of Carbonyls and Alkenes with Reducing Reagents Giving Six- and Seven-membered Benzocycloalkanols
Y. Hayashi (2017)
Mechanistic Study of Nickel-Catalyzed Reductive Coupling of Ynoates and Aldehydes.
S. K. Rodrigo (2017)
Nickel-catalyzed highly chemo- and stereoselective borylative cyclization of 1,6-enynes with bis(pinacolato)diboron
Jen-Chieh Hsieh (2017)
Enantioselective synthesis of β-amino acid derivatives via nickel-promoted regioselective carboxylation of ynamides and rhodium-catalyzed asymmetric hydrogenation.
Nozomi Saito (2016)
Nickel(0)-catalyzed intramolecular reductive coupling of alkenes and aldehydes or ketones with hydrosilanes.
Yukari Hayashi (2016)
Synthesis of α-Halo-γ-hydroxyenamides by Titanium Tetrahalide Mediated Addition of Aldehydes or Ketones to Ynamides.
Yuto Yabuuchi (2016)
Impact of Ligand and Silane on the Regioselectivity in Catalytic Aldehyde–Alkyne Reductive Couplings: A Theoretical Study
T. Liu (2016)
Metal‐Catalyzed Multicomponent Reactions
A. Ros (2015)
Nickel-promoted highly regioselective carboxylation of aryl ynol ether and its application to the synthesis of chiral β-aryloxypropionic acid derivatives.
N. Saito (2015)
Catalytic Transformation of Aldehydes with Nickel Complexes through η(2) Coordination and Oxidative Cyclization.
Y. Hoshimoto (2015)
Regiocontrol in Catalytic Reductive Couplings through Alterations of Silane Rate Dependence
Evan P. Jackson (2015)
Organoselenium-catalyzed, hydroxy-controlled regio- and stereoselective amination of terminal alkenes: efficient synthesis of 3-amino allylic alcohols.
Zhimin Deng (2015)
Carbene‐Promoted Multicomponent Reactions
D. Monge (2015)
CuI-catalyzed coupling of gem-dibromovinylanilides and sulfonamides: an efficient method for the synthesis of 2-amidoindoles and indolo[1,2-a]quinazolines.
Selvarangam E. Kiruthika (2014)
Studies on copper(I)-catalyzed highly regio- and stereo-selective hydroboration of alkynamides.
Guangke He (2014)
Palladium‐Catalyzed Addition of 1,3‐Diones to Ynamides: An Entry to Alkoxy‐Substituted Enamides
Lionel V. Graux (2014)
Metal-catalyzed synthesis of hetero-substituted alkenes and alkynes
Gwilherm Evano (2014)
Regiocontrolled palladium-catalyzed arylative cyclizations of alkynols.
Daishi Fujino (2014)
Ni-Catalyzed Three-component Coupling Reaction of Conjugated Enyne, Carbonyls, and Dimethylzinc to Construct Allenyl Alcohols
Y. Mori (2014)
Copper(I)‐Catalyzed Highly Regio‐ and Stereoselective Boron Addition–Protonolysis of Alkynamides to give Alkenamides
Guangke He (2013)
Transition-metal-catalyzed laboratory-scale carbon-carbon bond-forming reactions of ethylene.
Vaneet Saini (2013)
Nickel-catalyzed regio- and diastereoselective intermolecular three-component coupling of oxabicyclic alkenes with alkynes and organoboronic acids.
S. Mannathan (2013)
Nickel-catalyzed ring-opening alkylative coupling of enone with methylenecyclopropane in the presence of triethylborane.
Kenichi Ogata (2013)
Regio- and stereoselective carbometallation reactions of N-alkynylamides and sulfonamides
Yury Minko (2013)
Mechanistic exploration of the palladium-catalyzed process for the synthesis of benzoxazoles and benzothiazoles.
Valentin N. Bochatay (2013)
Übergangsmetallkatalysierte C‐C‐Kupplungen mit Ethylen im Labormaßstab
Vaneet Saini (2013)
Regio‐ and Stereoselective Synthesis of Tri‐ and Tetrasubstituted Enamides via Palladium‐Catalyzed Silaboration of Ynamides
N. Saito (2013)
Total synthesis of (-)-herbindoles A, B, and C via transition-metal-catalyzed intramolecular [2 + 2 + 2] cyclization between ynamide and diynes.
N. Saito (2012)See more