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Inositol Trisphosphate, A Novel Second Messenger In Cellular Signal Transduction

M. Berridge, R. Irvine
Published 1984 · Biology, Medicine

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There has recently been rapid progress in understanding receptors that generate intracellular signals from inositol lipids. One of these lipids, phosphatidylinositol 4,5-bisphosphate, is hydrolysed to diacylglycerol and inositol trisphosphate as part of a signal transduction mechanism for controlling a variety of cellular processes including secretion, metabolism, phototransduction and cell proliferation. Diacylglycerol operates within the plane of the membrane to activate protein kinase C, whereas inositol trisphosphate is released into the cytoplasm to function as a second messenger for mobilizing intracellular calcium.
This paper references
10.1111/J.1753-4887.1989.TB02827.X
Enzyme secretion and the incorporation of P32 into phospholipides of pancreas slices.
M. R. Hokin (1953)
10.1126/SCIENCE.165.3896.862
Acetylcholine action: biochemical aspects.
J. Durell (1969)
10.1085/JGP.59.6.701
The Effects of Intracellular Iontophoretic Injection of Calcium and Sodium Ions on the Light Response of Limulus Ventral Photoreceptors
J. Lisman (1972)
10.1016/0304-4157(75)90017-9
Inositol phospholipids and cell surface receptor function.
R. Michell (1975)
10.1042/BJ1620061
Acetylcholine increases the breakdown of triphosphoinositide of rabbit iris muscle prelabelled with [32P] phosphate.
A. A. Abdel-latif (1977)
Membrane transduction mechanisms
R. Cone (1979)
10.1016/0014-4827(79)90333-1
Potentiation of phytohemagglutinin stimulation of lymphoid cells by lithium.
D. Hart (1979)
10.1073/PNAS.76.2.837
Electrical currents through full-grown and maturing Xenopus oocytes.
K. Robinson (1979)
10.1083/JCB.80.2.372
Localization of sarcoplasmic reticulum proteins in rat skeletal muscle by immunofluorescence
A. Jorgensen (1979)
10.1146/ANNUREV.PH.42.030180.001015
The exocrine pancreas: the role of secretagogues, cyclic nucleotides, and calcium in enzyme secretion.
I. Schulz (1980)
10.1016/s0021-9258(19)70391-3
The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain.
L. Hallcher (1980)
10.1042/BJ1920783
Requirement for calcium ions in acetylcholine-stimulated phosphodiesteratic cleavage of phosphatidyl-myo-inositol 4,5-bisphosphate in rabbit iris smooth muscle.
R. Akhtar (1980)
10.1016/0165-6147(81)90273-X
Why is phosphatidylinositol degraded in response to stimulation of certain receptors
R. Michell (1981)
10.1016/0014-4827(81)90004-5
Growth effects of lithium chloride in BALB/c 3T3 fibroblasts and Madin-Darby canine kidney epithelial cells.
S. Rybak (1981)
10.1098/RSTB.1981.0177
The stimulation of inositol lipid metabolism that accompanies calcium mobilization in stimulated cells: defined characteristics and unanswered questions.
R. Michell (1981)
10.1007/978-1-349-05555-5_3
Interactions of muscarinic receptors with guanine nucleotides and adenylate cyclase
E. Hulme (1981)
10.1152/PHYSREV.1981.61.4.914
Regulation of insulin release by calcium.
C. Wollheim (1981)
10.1098/RSTB.1981.0169
Receptor regulation of calcium release and calcium permeability in parotid gland cells.
J. Putney (1981)
10.1021/BI00524A057
Enhancement of calcium uptake and phosphatidylinositol turnover by epidermal growth factor in A-431 cells.
S. Sawyer (1981)
10.1126/SCIENCE.6782676
Excitation of Limulus photoreceptors by vanadate and by a hydrolysis-resistant analog of guanosine triphosphate.
A. Fein (1981)
10.1016/s0021-9258(18)43275-9
Early changes in phosphatidylinositol and arachidonic acid metabolism in quiescent swiss 3T3 cells stimulated to divide by platelet-derived growth factor.
A. Habenicht (1981)
10.1016/0165-6147(81)90360-6
Does phosphatidylinositol breakdown control the Ca2+-gating mechanism?
S. Cockcroft (1981)
10.1007/978-1-349-05555-5
Drug receptors and their effectors
N. Birdsall (1981)
10.1016/s0021-9258(18)33801-8
Hepatic alpha 1-adrenergic receptors show agonist-specific regulation by guanine nucleotides. Loss of nucleotide effect after adrenalectomy.
M. Goodhardt (1982)
10.1042/BJ2040003
How is the level of free arachidonic acid controlled in mammalian cells?
R. Irvine (1982)
10.1113/jphysiol.1982.sp014257
Cholinergic and catecholaminergic receptors in the Xenopus oocyte membrane
K. Kusano (1982)
10.1016/0143-4160(82)90031-8
Phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate: lipids in search of a function.
P. Downes (1982)
10.1113/jphysiol.1982.sp014416
Injection of guanosine and adenosine nucleotides into Limulus ventral photoreceptor cells
S. Bolsover (1982)
10.1038/296091A0
Triphosphoinositide increases glycoprotein lateral mobility in erythrocyte membranes
M. Sheetz (1982)
10.1016/s0021-9258(18)34459-4
Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.
M. Castagna (1982)
10.1042/BJ2030169
The inositol trisphosphate phosphomonoesterase of the human erythrocyte membrane.
C. Downes (1982)
10.1016/0143-4160(82)90028-8
Inositol lipid metabolism in dividing and differentiating cells.
R. Michell (1982)
10.1038/298669A0
Insertion of diphtheria toxin into and across membranes: role of phosphoinositide asymmetry
J. J. Donovan (1982)
10.1016/s0021-9258(18)33568-3
Rapid decrease of phosphatidylinositol 4,5-bisphosphate in thrombin-stimulated platelets.
M. Billah (1982)
10.1042/BJ2060587
Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands.
M. Berridge (1982)
10.1016/s0021-9258(19)68345-6
alpha-Adrenergic activation of phosphorylase in liver cells involves mobilization of intracellular calcium without influx of extracellular calcium.
P. Blackmore (1982)
10.1016/0143-4160(82)90018-5
The enzymology of stimulated inositol lipid turnover.
R. Irvine (1982)
10.1073/PNAS.80.20.6224
Platelet-derived growth factor stimulates Na+/H+ exchange and induces cytoplasmic alkalinization in NR6 cells.
D. Cassel (1983)
10.1038/304645A0
Na+/H+ exchange and cytoplasmic pH in the action of growth factors in human fibroblasts
W. Moolenaar (1983)
10.1042/BJ2120849
Rapid accumulation of inositol trisphosphate reveals that agonists hydrolyse polyphosphoinositides instead of phosphatidylinositol.
M. Berridge (1983)
10.1126/SCIENCE.6304883
Simian sarcoma virus onc gene, v-sis, is derived from the gene (or genes) encoding a platelet-derived growth factor.
R. Doolittle (1983)
10.1016/s0021-9258(18)32882-5
Thrombin-induced phosphodiesteratic cleavage of phosphatidylinositol bisphosphate in human platelets.
B. Agranoff (1983)
10.1146/ANNUREV.BI.52.070183.001505
Cellular oncogenes and retroviruses.
J. Bishop (1983)
10.1016/0006-291X(83)91619-4
Serum rapidly mobilizes calcium from an intracellular pool in quiescent fibroblastic cells.
A. López-Rivas (1983)
10.1007/BF01140658
Polyphosphoinositide metabolism in excitable membranes
J. Hawthorne (1983)
10.1038/306064A0
Involvement of guanine nucleotide-binding protein in the gating of Ca2+ by receptors
B. Gomperts (1983)
10.1042/BJ2120733
Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones.
J. Creba (1983)
10.1016/s0021-9258(17)43734-3
Thyrotropin-releasing hormone rapidly activates the phosphodiester hydrolysis of polyphosphoinositides in GH3 pituitary cells. Evidence for the role of a polyphosphoinositide-specific phospholipase C in hormone action.
T. Martin (1983)
10.1016/0014-5793(83)81028-X
Coupling of polyphosphoinositide breakdown with calcium efflux in formyl‐methionyl‐leucyl‐phenylalanine‐stimulated rabbit neutrophils
K. Yano (1983)
10.1016/S0006-291X(83)80231-9
Serum, platelet-derived growth factor, vasopressin and phorbol esters increase intracellular pH in Swiss 3T3 cells.
C. Burns (1983)
10.1042/BJ2160633
Breakdown of polyphosphoinositides and not phosphatidylinositol accounts for muscarinic agonist-stimulated inositol phospholipid metabolism in rat parotid glands.
C. Downes (1983)
10.1016/0014-5793(83)80944-2
The phorbol ester TPA increases the affinity of exocytosis for calcium in ‘leaky’ adrenal medullary cells
D. Knight (1983)
10.1042/BJ2160101
Identification and metabolism of polyphosphoinositides in isolated islets of Langerhans.
S. G. Laychock (1983)
10.1042/BJ2160287
Thyroliberin stimulates rapid hydrolysis of phosphatidylinositol 4,5-bisphosphate by a phosphodiesterase in rat mammotropic pituitary cells. Evidence for an early Ca2+-independent action.
M. Rebecchi (1983)
10.1042/BJ2120473
Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides.
M. Berridge (1983)
10.1002/JCP.1041170303
Growth effect of lithium on mouse mammary epithelial cells in serum‐free collagen gel culture
Y. Tomooka (1983)
10.1042/BJ2160299
The kinetics of dissociation of the inhibitor of nucleoside transport, nitrobenzylthioinosine, from the high-affinity binding sites of cultured hamster cells.
R. Koren (1983)
10.1016/s0021-9258(17)44442-5
Acetylglyceryl ether phosphorylcholine. A potent activator of hepatic phosphoinositide metabolism and glycogenolysis.
S. Shukla (1983)
10.1038/306067A0
Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate
H. Streb (1983)
10.1016/0014-5793(83)81113-2
A rapid stimulation of phosphatidylinositol metabolism in rabbit leukocytes by pseudomonal leukocidin
T. Hirayama (1983)
10.1016/0014-5793(83)80205-1
Muscarinic stimulation of phospholipid turnover in dissociated avian salt gland cells
S. Fisher (1983)
10.1016/0006-291X(83)91711-4
Chemotactic factor causes rapid decreases in phosphatidylinositol,4,5-bisphosphate and phosphatidylinositol 4-monophosphate in rabbit neutrophils.
M. Volpi (1983)
10.1038/304035a0
Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus
M. Waterfield (1983)
10.1210/ENDO-113-6-2268
Regulation of Ca2+-Mg2+-ATPase activity in hepatocyte plasma membranes by vasopressin and phenylephrine.
S. Lin (1983)
10.1016/0005-2760(83)90147-9
Phytohemagglutinin induces rapid degradation of phosphatidylinositol 4, 5-bisphosphate and transient accumulation of phosphatidic acid and diacylglycerol in a human T lymphoblastoid cell line, CCRF-CEM
Hiroko Sasaki (1983)
10.1016/0012-1606(83)90276-2
Sources of calcium in egg activation: a review and hypothesis.
L. Jaffe (1983)
10.1016/0003-9861(83)90492-7
An early transient decrease in phosphatidylinositol 4,5-bisphosphate upon stimulation of rabbit platelets with acetylglycerylether phosphorylcholine (platelet activating factor).
S. Shukla (1983)
10.1016/0006-291X(83)91751-5
ADP-induced changes in [32P]phosphate labeling of phosphatidylinositol-4,5-bisphosphate in washed rabbit platelets made refractory by prior ADP stimulation.
N. Leung (1983)
10.1038/305317A0
Diacylglycerol and phorbol ester stimulate secretion without raising cytoplasmic free calcium in human platelets
T. J. Rink (1983)
10.1038/311273A0
The product of ras is a GTPase and the T24 oncogenic mutant is deficient in this activity
R. Sweet (1984)
10.1016/S0006-291X(84)80186-2
Inositol (1,4,5)trisphosphate-promoted Ca2+ release from microsomal fractions of rat liver.
A. Dawson (1984)
10.1016/s0021-9258(17)39693-x
Differential effect of pertussis toxin on the affinity state for agonists of renal alpha 1- and alpha 2- adrenoceptors.
J. Boyer (1984)
10.1152/AJPCELL.1984.246.1.C141
Phosphoinositide breakdown in blowfly salivary glands.
I. Litosch (1984)
10.1016/0014-5793(84)80811-X
12‐O‐Tetradecanoylphorbol 13‐acetate stimulates inositol lipid phosphorylation in intact human platelets
D. de Chaffoy de Courcelles (1984)
10.1038/310414A0
Fertilization increases the polyphosphoinositide content of sea urchin eggs
P. Turner (1984)
10.1038/309066A0
Cyclic nucleotides control a system which regulates Ca2+ sensitivity of platelet secretion
D. Knight (1984)
10.1042/BJ2230237
Inositol trisphosphates in carbachol-stimulated rat parotid glands.
R. Irvine (1984)
10.1016/0014-5793(84)81084-4
Guanine nucleotides decrease the free [Ca2+] required for secretion of serotonin from permeabilized blood platelets
R. Haslam (1984)
10.1016/0303-7207(84)90082-0
Relationship of polyphosphoinositide metabolism to the hormonal activation of the inset salivary gland by 5-hydroxytryptamine
M. Berridge (1984)
10.1016/s0021-9258(17)43262-5
myo-Inositol 1,4,5-trisphosphate. A second messenger for the hormonal mobilization of intracellular Ca2+ in liver.
S. Joseph (1984)
10.1042/BJ2230229
Release of Ca2+ from a non-mitochondrial store site in peritoneal macrophages treated with saponin by inositol 1,4,5-trisphosphate.
M. Hirata (1984)
10.1038/310644A0
Comparative biochemical properties of normal and activated human ras p21 protein
J. Mcgrath (1984)
10.1172/JCI111284
Phorbol myristate acetate stimulates ATP-dependent calcium transport by the plasma membrane of neutrophils.
H. Lagast (1984)
10.1042/BJ2180177
Phosphatidylinositol-4,5-bisphosphate phosphodiesterase and phosphomonoesterase activities of rat brain. Some properties and possible control mechanisms.
R. Irvine (1984)
10.1016/s0021-9258(17)43414-4
Vasopressin-, angiotensin II-, and alpha 1-adrenergic-induced inhibition of Ca2+ transport by rat liver plasma membrane vesicles.
V. Prpic (1984)
10.1016/0092-8674(84)90336-2
G proteins and dual control of adenylate cyclase
A. Gilman (1984)
10.1042/BJ2200345
Inositol trisphosphate and diacylglycerol as second messengers.
M. Berridge (1984)
10.1042/BJ2220269
Specificity of inositol trisphosphate-induced calcium release from permeabilized Swiss-mouse 3T3 cells.
R. Irvine (1984)
10.1016/s0021-9258(17)39848-4
The calcium signal and phosphatidylinositol breakdown in 2H3 cells.
M. Beaven (1984)
10.1021/BI00306A004
Light-regulated biochemical events in invertebrate photoreceptors. 2. Light-regulated phosphorylation of rhodopsin and phosphoinositides in squid photoreceptor membranes.
C. Vandenberg (1984)
10.1016/0014-5793(84)80483-4
Effects of lithium on angiotensin‐stimulated phosphatidylinositol turnover and aldosterone production in adrenal glomerulosa cells: a possible causal relationship
T. Balla (1984)
10.1073/PNAS.81.7.2117
Evidence that the Rous sarcoma virus transforming gene product phosphorylates phosphatidylinositol and diacylglycerol.
Y. Sugimoto (1984)
10.1038/311160A0
myo-inositol polyphosphate may be a messenger for visual excitation in Limulus photoreceptors
J. E. Brown (1984)
10.1042/BJ2220351
Potentiation by thrombin of the secretion of serotonin from permeabilized platelets equilibrated with Ca2+ buffers. Relationship to protein phosphorylation and diacylglycerol formation.
R. Haslam (1984)
10.1038/NBT0684-541
Oncogenes, Inositol Lipids and Cellular Proliferation
M. Berridge (1984)
10.1042/BJ2210803
Rapid accumulation of inositol phosphates in isolated rat superior cervical sympathetic ganglia exposed to V1-vasopressin and muscarinic cholinergic stimuli.
E. Bone (1984)
10.1038/309063A0
The second messenger linking receptor activation to internal Ca release in liver
G. Burgess (1984)
10.1038/308693A0
The role of protein kinase C in cell surface signal transduction and tumour promotion
Y. Nishizuka (1984)
10.1016/s0021-9258(17)39836-8
Phorbol esters induce differentiation in a pre-B-lymphocyte cell line by enhancing Na+/H+ exchange.
P. Rosoff (1984)
10.1042/BJ2180819
Stimulus-response coupling in human platelets. Changes evoked by platelet-activating factor in cytoplasmic free calcium monitored with the fluorescent calcium indicator quin2.
T. Hallam (1984)
Bradykinin-induced rapid breakdown of phosphatidylinositol 4,5-bisphosphate in neuroblastoma X glioma hybrid NG108-15 cells.
K. Yano (1984)
10.1016/0014-5793(84)80316-6
Some mitogens cause rapid increases in free calcium in fibroblasts
J. Morris (1984)
10.1210/ENDO-114-1-302
Rapid effects of angiotensin-II on polyphosphoinositide metabolism in the rat adrenal glomerulosa.
R V Farese (1984)
10.1016/0006-291X(84)90772-1
Phorbol diesters promote beta-adrenergic receptor phosphorylation and adenylate cyclase desensitization in duck erythrocytes.
D. Sibley (1984)
10.1073/PNAS.81.14.4316
Phorbol ester induces desensitization of adenylate cyclase and phosphorylation of the beta-adrenergic receptor in turkey erythrocytes.
D. Kelleher (1984)
10.1083/JCB.99.1.83
Thyrotropin-releasing hormone increases cytosolic free Ca2+ in clonal pituitary cells (GH3 cells): direct evidence for the mobilization of cellular calcium
W. Schlegel (1984)
10.1016/0006-291X(84)90424-8
Reduction of epidermal growth factor receptor affinity by heterologous ligands: evidence for a mechanism involving the breakdown of phosphoinositides and the activation of protein kinase C.
K. D. Brown (1984)
10.1016/0024-3205(84)90006-7
Metabolism of inositol phosphates in parotid cells: implications for the pathway of the phosphoinositide effect and for the possible messenger role of inositol trisphosphate.
D. Aub (1984)
10.1016/0014-5793(84)80816-9
Islet‐activating protein, pertussis toxin, inhibits Ca2+‐induced and guanine nucleotide‐dependent releases of histamine and arachidonic acid from rat mast cells
T. Nakamura (1984)
10.1042/BJ2230467
Inositol 1,4,5-trisphosphate mobilizes intracellular Ca2+ from permeabilized insulin-secreting cells.
T. Biden (1984)
10.1021/BI00306A003
Light-regulated biochemical events in invertebrate photoreceptors. 1. Light-activated guanosinetriphosphatase, guanine nucleotide binding, and cholera toxin catalyzed labeling of squid photoreceptor membranes.
C. Vandenberg (1984)
10.1038/309562A0
Rapid mobilization of Ca2+ from rat insulinoma microsomes by inositol-1,4,5-trisphosphate
M. Prentki (1984)
10.1002/j.1460-2075.1984.tb01911.x
Ionic responses rapidly elicited by porcine platelet‐derived growth factor in Swiss 3T3 cells.
A. López-Rivas (1984)
10.1016/s0021-9258(17)39690-4
Growth factors immediately raise cytoplasmic free Ca2+ in human fibroblasts.
W. Moolenaar (1984)
10.1038/310147A0
Epidermal growth factor stimulates guanine nucleotide binding activity and phosphorylation of ras oncogene proteins
T. Kamata (1984)
10.1038/307521A0
Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences
J. Downward (1984)
10.1002/JCP.1041190107
Prostaglandin F2α stimulates phosphatidylinositol turnover and increases the cellular content of 1,2‐diacylglycerol in confluent resting swiss 3T3 cells
C. Macphee (1984)
10.1113/jphysiol.1984.sp015310
Xenopus oocyte resting potential, muscarinic responses and the role of calcium and guanosine 3',5'‐cyclic monophosphate.
N. Dascal (1984)
10.1038/311157A0
Photoreceptor excitation and adaptation by inositol 1,4,5-trisphosphate
A. Fein (1984)
Relationship between inositol polyphosphate production and the increase of cytosolic free Ca2+ induced by vasopressin in isolated hepatocytes.
A. P. Thomas (1984)
10.1042/BJ2190655
Secretagogue-induced formation of inositol phosphates in rat exocrine pancreas. Implications for a messenger role for inositol trisphosphate.
R. Rubin (1984)
Inositol trisphosphate mediates thyrotropin-releasing hormone mobilization of nonmitochondrial calcium in rat mammotropic pituitary cells.
M. Gershengorn (1984)
10.1016/0006-291X(84)91279-8
Inositol 1,4,5-trisphosphate releases Ca2+ from intracellular store sites in skinned single cells of porcine coronary artery.
E. Suematsu (1984)
10.1073/PNAS.81.9.2728
Transforming protein of avian sarcoma virus UR2 is associated with phosphatidylinositol kinase activity: possible role in tumorigenesis.
I. Macara (1984)
10.1042/BJ2220195
Inositol trisphosphate formation and calcium mobilization in Swiss 3T3 cells in response to platelet-derived growth factor.
M. Berridge (1984)
10.1016/s0021-9258(17)42844-4
Subcellular site and mechanism of vasopressin-stimulated hydrolysis of phosphoinositides in rat hepatocytes.
M. A. Seyfred (1984)
10.1016/s0021-9258(17)42826-2
Alpha 1-adrenergic receptor activation mobilizes cellular Ca2+ in a muscle cell line.
R. Brown (1984)
10.1016/0092-8674(84)90310-6
Activation of ras genes in human tumors does not affect localization, modification, or nucleotide binding properties of p21
T. Finkel (1984)
10.1042/BJ2220307
Secretagogue-induced phosphoinositide metabolism in human leucocytes.
R. Dougherty (1984)



This paper is referenced by
10.2183/pjab.97.022
Okamoto model for necrosis and its expansions, CD38-cyclic ADP-ribose signal system for intracellular Ca2+ mobilization and Reg (Regenerating gene protein)-Reg receptor system for cell regeneration
Hiroshi OKAMOTO (2021)
10.37349/ent.2021.00008
Striking a balance: PIP2 and PIP3 signaling in neuronal health and disease
K. Tariq (2021)
10.3389/fphys.2021.676907
Functional Characterization of Olfactory Receptors in the Thyroid Gland
D. Weidinger (2021)
10.1021/acs.jproteome.1c00813
Comprehensive Identification of Regulatory Protein Networks.
Luke Khoury (2021)
10.1038/s41598-021-85895-y
Randomized, crossover clinical efficacy trial in humans and mice on tear secretion promotion and lacrimal gland protection by molecular hydrogen
M. Kubota (2021)
10.1177/25152564211008341
Emerging Evidence for cAMP-calcium Cross Talk in Heart Atrial Nanodomains Where IP3-Evoked Calcium Release Stimulates Adenylyl Cyclases
R. Burton (2021)
10.3390/jof7060470
Inositol Signaling in the Basidiomycete Fungus Schizophyllum commune
Reyna Murry (2021)
10.1242/bio.058833
Regulated inositol synthesis is critical for balanced metabolism and development in Drosophila melanogaster
M. Rivera (2021)
10.1007/s00424-021-02609-z
Mechanisms underlying spontaneous phasic contractions and sympathetic control of smooth muscle in the rat caudal epididymis.
R. Mitsui (2021)
10.1007/978-1-0716-1142-5_6
Imaging the Nanoscale Distribution of Phosphoinositides in the Cell Plasma Membrane with Single-Molecule Localization Super-Resolution Microscopy.
F. Fan (2021)
10.1007/978-3-030-63650-0_6
Polycystic Ovary Syndrome: Considerations About Therapeutic Strategies Choices from Fertile Life to Menopause
Alessandro D. Genazzani (2021)
10.1101/2021.05.10.441946
Endoplasmic Reticulum morphological regulation by RTN4/NOGO modulates neuronal regeneration by curbing luminal transport
Tasuku Konno (2021)
10.1016/j.str.2021.10.002
Structural evidence for visual arrestin priming via complexation of phosphoinositols.
Christopher L. Sander (2021)
10.1016/j.drudis.2021.01.030
Gold nanoparticles: synthesis, physiochemical properties and therapeutic applications in cancer.
Xin-yu Liu (2021)
10.1016/b978-0-12-819460-7.00063-3
Lipids | Phospholipase C
Angeline M. Lyon (2021)
10.3390/membranes11080562
Lipid Transporters Beam Signals from Cell Membranes
Miliça Ristovski (2021)
10.7554/eLife.61951
α-Synuclein plasma membrane localization correlates with cellular phosphatidylinositol polyphosphate levels
R. Jacob (2021)
10.1016/j.jchromb.2021.122603
Screening of lipid metabolism biomarkers in patients with coronary heart disease via ultra-performance liquid chromatography-high resolution mass spectrometry.
Fang Cai (2021)
10.1371/journal.ppat.1009635
Recruitment of phospholipase Cγ1 to the non-structural membrane protein pK15 of Kaposi Sarcoma-associated herpesvirus promotes its Src-dependent phosphorylation
N. Samarina (2021)
10.1152/physrev.00041.2020
Mitochondrial calcium exchange in physiology and disease.
Joanne F Garbincius (2021)
10.1126/scisignal.abc6612
Emerging roles of PLCγ1 in endothelial biology
Dongying Chen (2021)
10.1016/j.neubiorev.2020.01.012
Dietary phospholipids: Role in cognitive processes across the lifespan
M. Schverer (2020)
10.1111/bjd.19115
New effects of caffeine on corticotropin‐releasing hormone (CRH)‐induced stress along the intrafollicular classical hypothalamic–pituitary–adrenal (HPA) axis (CRH‐R1/2, IP3‐R, ACTH, MC‐R2) and the neurogenic non‐HPA axis (substance P, p75NTR and TrkA) in ex vivo human male androgenetic scalp hair fo
T.W. Fischer (2020)
10.2174/1381612826666200813132951
Role of histamine as a peripheral sympathetic neuromediator and its interrelation with substance P.
A. S. M. Atencio (2020)
10.3390/ijms21103642
Structural Mechanisms of Store-Operated and Mitochondrial Calcium Regulation: Initiation Points for Drug Discovery
Megan Noble (2020)
10.1016/j.ceca.2020.102247
Orai3: Oncochannel with therapeutic potential.
Jyoti Tanwar (2020)
10.1021/acs.orglett.0c01226
Phosphorylation Organocatalysts Highly Active by Design.
Amit Fallek (2020)
10.1038/s41431-020-00749-x
Pontocerebellar hypoplasia due to bi-allelic variants in MINPP1
B. Appelhof (2020)
10.1201/9781003066101-18
Lipocortins, a Family of Phospholipase A2-Inhibitory Proteins
B. Wallner (2020)
10.1152/ajpheart.00380.2020
IP3-mediated Ca2+ release regulates atrial Ca2+ transients and pacemaker function by stimulation of adenylyl cyclases
Rebecca A. Capel (2020)
10.1007/978-1-0716-0167-9_1
A Short Historical Perspective of Methods in Inositol Phosphate Research.
S. Shears (2020)
10.1016/j.semcdb.2020.08.012
The role of lipids in the central nervous system and their pathological implications in amyotrophic lateral sclerosis.
T. Tracey (2020)
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