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Expression Of Trehalose-6-phosphate Phosphatase In Maize Ears Improves Yield In Well-watered And Drought Conditions

Michael L Nuccio, Jeff Wu, R. Mowers, Huaping Zhou, Moez Meghji, Lucia F. Primavesi, M. Paul, X. Chen, Y. Gao, E. Haque, S. S. Basu, L. M. Lagrimini
Published 2015 · Medicine, Biology

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Maize, the highest-yielding cereal crop worldwide, is particularly susceptible to drought during its 2- to 3-week flowering period. Many genetic engineering strategies for drought tolerance impinge on plant development, reduce maximum yield potential or do not translate from laboratory conditions to the field. We overexpressed a gene encoding a rice trehalose-6-phosphate phosphatase (TPP) in developing maize ears using a floral promoter. This reduced the concentration of trehalose-6-phosphate (T6P), a sugar signal that regulates growth and development, and increased the concentration of sucrose in ear spikelets. Overexpression of TPP increased both kernel set and harvest index. Field data at several sites and over multiple seasons showed that the engineered trait improved yields from 9% to 49% under non-drought or mild drought conditions, and from 31% to 123% under more severe drought conditions, relative to yields from nontransgenic controls.
This paper references
10.1104/pp.108.133934
Inhibition of SNF1-Related Protein Kinase1 Activity and Regulation of Metabolic Pathways by Trehalose-6-Phosphate1[W][OA]
Y. Zhang (2009)
10.1002/WICS.162
JMP statistical discovery software
B. Jones (2011)
10.1093/JEXBOT/51.SUPPL_1.447
Selectable traits to increase crop photosynthesis and yield of grain crops.
R. Richards (2000)
10.2139/ssrn.2222269
Predicting Agricultural Impacts of Large-Scale Drought: 2012 and the Case for Better Modeling
Joshua Elliott (2013)
10.1038/379683A0
Drought tolerance in tobacco
Kjell-Ove Holmström (1996)
10.1104/pp.107.1.125
Improved Performance of Transgenic Fructan-Accumulating Tobacco under Drought Stress
EAH. Pilon-Smits (1995)
10.1126/science.1068275
A Draft Sequence of the Rice Genome (Oryza sativa L. ssp. japonica)
J. Yu (2002)
10.1111/J.1365-313X.2007.03272.X
The D-lineage MADS-box gene OsMADS13 controls ovule identity in rice.
Ludovico Dreni (2007)
10.2135/cropsci1991.0011183X003100050024x
Maize Kernel set at low water potential. II, Sensitivity to reduced assimilates at pollination
J. R. Schussler (1991)
10.1016/S0065-2113(08)60843-3
Reproductive Development in Grain Crops during Drought
H. Saini (1999)
Gapped BLAST and PSI-BLAST: A new
D. Lipman (1997)
10.1104/pp.007237
Expression of a Bifunctional Fusion of the Escherichia coli Genes for Trehalose-6-Phosphate Synthase and Trehalose-6-Phosphate Phosphatase in Transgenic Rice Plants Increases Trehalose Accumulation and Abiotic Stress Tolerance without Stunting Growth1
I. Jang (2003)
10.1093/mp/ssq044
Sugar input, metabolism, and signaling mediated by invertase: roles in development, yield potential, and response to drought and heat.
Y. Ruan (2010)
10.1111/j.1742-4658.2007.05658.x
Biochemical characterization of rice trehalose‐6‐phosphate phosphatases supports distinctive functions of these plant enzymes
Shuhei Shima (2007)
Genetic engineering of drought resistant potato plants by introduction of the trehalose-6-phosphate synthase (TPS1) gene from Saccharomyces cerevisiae.
Yeo Et (2000)
10.1104/pp.111.176818
The ZmASR1 Protein Influences Branched-Chain Amino Acid Biosynthesis and Maintains Kernel Yield in Maize under Water-Limited Conditions1[W][OA]
Laetitia Virlouvet (2011)
A draft sequence of the rice genome (Oryza sativa L. ssp. japonica).
S. Goff (2002)
10.1093/JXB/ERH219
Grain yields with limited water.
John S. Boyer (2004)
10.1104/PP.124.1.71
A maize vacuolar invertase, IVR2, is induced by water stress. Organ/tissue specificity and diurnal modulation of expression.
J. Y. Kim (2000)
10.2144/01311RR04
Quantitative real-time PCR assay for determining transgene copy number in transformed plants.
D. J. Ingham (2001)
10.1016/J.FCR.2007.07.004
Drought tolerance improvement in crop plants: An integrated view from breeding to genomics
L. Cattivelli (2008)
10.1046/J.1365-3040.1997.D01-89.X
Effect of water restriction on carbohydrate metabolism and photosynthesis in mature maize leaves
S. Pelleschi (1997)
10.1046/J.1365-313X.1998.00064.X
Trehalose-6-phosphate phosphatases from Arabidopsis thaliana: identification by functional complementation of the yeast tps2 mutant.
G. Vogel (1998)
10.1007/s00425-011-1458-0
Overexpression of the trehalose-6-phosphate synthase gene OsTPS1 enhances abiotic stress tolerance in rice
H. Li (2011)
10.1104/PP.010765
Desiccation tolerance in the resurrection plant Craterostigma plantagineum. A contribution to the study of drought tolerance at the molecular level.
D. Bartels (2001)
10.1007/s00425-007-0579-y
A bifunctional TPS–TPP enzyme from yeast confers tolerance to multiple and extreme abiotic-stress conditions in transgenic Arabidopsis
J. A. Miranda (2007)
10.1126/science.218.4571.443
Plant Productivity and Environment
J. Boyer (1982)
HEP computing : where are we now? - open questions for the CHEP'91 conference
J. Thresher (1992)
10.2135/CROPSCI1995.0011183X003500040026X
Assimilate Flux Determines Kernel Set at Low Water Potential in Maize
J. R. Schussler (1995)
10.2135/cropsci1991.0011183X003100050023x
Maize Kernel Set at Low Water Potential: I. Sensitivity to Reduced Assimilates during Early Kernel Growth
J. R. Schussler (1991)
10.1093/jxb/ert457
The sucrose–trehalose 6-phosphate (Tre6P) nexus: specificity and mechanisms of sucrose signalling by Tre6P
U. Yadav (2014)
10.1002/9780470650301.CH7
Improving Drought Tolerance in Maize
T. A. Barker (2010)
10.1007/s11103-007-9159-6
Improved drought tolerance without undesired side effects in transgenic plants producing trehalose
Sazzad Karim (2007)
10.1073/pnas.0602316103
SNF1-related kinases allow plants to tolerate herbivory by allocating carbon to roots
J. Schwachtje (2006)
10.1371/journal.pone.0066428
Yield Trends Are Insufficient to Double Global Crop Production by 2050
D. Ray (2013)
10.1023/A:1026429922616
Identification of a rice APETALA3 homologue by yeast two-hybrid screening
Y. Moon (2004)
10.1016/J.PLANTSCI.2005.02.026
Tomato abiotic stress enhanced tolerance by trehalose biosynthesis
Carolina Cortina (2005)
10.1093/mp/ssn068
Evaluation of seven function-known candidate genes for their effects on improving drought resistance of transgenic rice under field conditions.
Ben-Ze Xiao (2009)
10.1002/(SICI)1520-6408(1999)25:3<237::AID-DVG6>3.0.CO;2-L
OsMADS13, a novel rice MADS-box gene expressed during ovule development.
Z. Lopez-Dee (1999)
10.1007/s004250050069
Expression of the yeast trehalose-6-phosphate synthase gene in transgenic tobacco plants: pleiotropic phenotypes include drought tolerance
C. Romero (2009)
10.1104/pp.111.174524
Wheat Grain Development Is Characterized by Remarkable Trehalose 6-Phosphate Accumulation Pregrain Filling: Tissue Distribution and Relationship to SNF1-Related Protein Kinase1 Activity1[W][OA]
E. Martínez-Barajas (2011)
10.1016/j.plaphy.2012.11.011
Inhibition of SnRK1 by metabolites: tissue-dependent effects and cooperative inhibition by glucose 1-phosphate in combination with trehalose 6-phosphate.
Cátia Nunes (2013)
10.1073/pnas.0707193104
Plant nuclear factor Y (NF-Y) B subunits confer drought tolerance and lead to improved corn yields on water-limited acres
D. E. Nelson (2007)
10.1007/s11103-005-7404-4
Functional Identification of a Trehalose 6-phosphate Phosphatase Gene that is Involved in Transient Induction of Trehalose Biosynthesis during Chilling Stress in Rice
M. Habibur Rahman Pramanik (2005)
10.2135/CROPSCI1995.0011183X003500050022X
Reversing Drought-Induced Losses in Grain Yield: Sucrose Maintains Embryo Growth in Maize
C. Zinselmeier (1995)
10.1073/pnas.252637799
Trehalose accumulation in rice plants confers high tolerance levels to different abiotic stresses
A. Garg (2002)
10.1104/pp.107.2.385
Low Water Potential Disrupts Carbohydrate Metabolism in Maize (Zea mays L.) Ovaries
C. Zinselmeier (1995)
10.1073/pnas.1132018100
Trehalose 6-phosphate is indispensable for carbohydrate utilization and growth in Arabidopsis thaliana
H. Schluepmann (2003)
10.1038/cr.2009.143
The AGL6-like gene OsMADS6 regulates floral organ and meristem identities in rice
H. Li (2010)
10.1038/nature04725
A trehalose metabolic enzyme controls inflorescence architecture in maize
Namiko Satoh-Nagasawa (2006)
10.1093/jxb/err311
Metabolism control over growth: a case for trehalose-6-phosphate in plants.
H. Schluepmann (2012)
10.1038/ncomms3918
Distinguishing between yield advances and yield plateaus in historical crop production trends
P. Grassini (2013)
10.1104/pp.113.220657
The Trehalose 6-Phosphate/SnRK1 Signaling Pathway Primes Growth Recovery following Relief of Sink Limitation1[W][OA]
C. Nunes (2013)
10.1111/pbi.12172
Transgenic alteration of ethylene biosynthesis increases grain yield in maize under field drought-stress conditions.
J. Habben (2014)
10.1111/j.1365-313X.2010.04354.x
OsMADS6 plays an essential role in endosperm nutrient accumulation and is subject to epigenetic regulation in rice (Oryza sativa).
J. Zhang (2010)
10.1023/A:1022100404542
Accumulation of trehalose within transgenic chloroplasts confers drought tolerance
S. Lee (2004)
10.1146/annurev.arplant.59.032607.092945
Trehalose metabolism and signaling.
M. Paul (2008)
10.4161/psb.23209
Redundant and non-redundant roles of the trehalose-6-phosphate phosphatases in leaf growth, root hair specification and energy-responses in Arabidopsis
Hilde Van Houtte (2013)
10.4161/psb.5.4.10792
Up-regulation of biosynthetic processes associated with growth by trehalose 6-phosphate
M. Paul (2010)
10.1093/AOB/MCF049
Plant breeding and drought in C3 cereals: what should we breed for?
J. L. Araus (2002)
Identification and Characterization of Three Orchid MADS-Box Genes of the AP 1 / AGL 9 Subfamily during Floral Transition 1
H. Yu (2000)
10.3389/fphys.2012.00305
Phenotyping maize for adaptation to drought
J. Araus (2012)
10.1093/JXB/ERL177
Functional reversion to identify controlling genes in multigenic responses: analysis of floral abortion.
John S. Boyer (2007)
10.1186/1471-2164-8-242
MADS-box gene family in rice: genome-wide identification, organization and expression profiling during reproductive development and stress
R. Arora (2006)
10.1199/tab.0122
Trehalose Metabolites in Arabidopsis—elusive, active and central
H. Schluepmann (2009)
10.1016/J.FCR.2004.07.003
Improving drought tolerance in maize: a view from industry
H. Campos (2004)
10.15406/JIG.2015.02.00015
Microbial Symbionts: A Potential Bio-Boom
Mustafa R. Morsy (2015)
10.1104/pp.108.118828
Bacterial RNA Chaperones Confer Abiotic Stress Tolerance in Plants and Improved Grain Yield in Maize under Water-Limited Conditions[W]
P. Castiglioni (2008)
10.1007/s002999900187
The use of phosphomannose-isomerase as a selectable marker to recover transgenic maize plants (Zea mays L.) via Agrobacterium transformation
D. Negrotto (2000)
10.1111/j.1744-7909.2012.01118.x
Phenotyping for abiotic stress tolerance in maize.
B. Masuka (2012)
10.1111/J.1399-3054.1993.TB00146.X
The unusual sugar composition in leaves of the resurrection plant Myrothamnus flabellifolia
G. Bianchi (1993)



This paper is referenced by
10.3389/fpls.2019.00566
Genetic Correlations Between Photosynthetic and Yield Performance in Maize Are Different Under Two Heat Scenarios During Flowering
Vlatko Galic (2019)
10.1371/journal.pone.0232294
Exogenous diethyl aminoethyl hexanoate ameliorates low temperature stress by improving nitrogen metabolism in maize seedlings
Jianguo Zhang (2020)
10.1104/pp.19.00693
Overexpression of ca1pase Decreases Rubisco Abundance and Grain Yield in Wheat1[CC-BY]
A. K. M. Lobo (2019)
10.1016/j.pestbp.2019.11.016
Characterization of trehalose-6-phosphate phosphatase in trehalose biosynthesis, asexual development, stress resistance and virulence of an insect mycopathogen.
Lei Qiu (2020)
10.1007/978-3-030-27423-8_10
Transgenic Plants Overexpressing Trehalose Biosynthetic Genes and Abiotic Stress Tolerance in Plants
Zsófia Bánfalvi (2019)
10.1016/j.chroma.2016.11.031
Analysis of low abundant trehalose-6-phosphate and related metabolites in Medicago truncatula by hydrophilic interaction liquid chromatography-triple quadrupole mass spectrometry.
A. T. Mata (2016)
10.1016/j.bbabio.2016.07.007
Metabolite transport and associated sugar signalling systems underpinning source/sink interactions
Cara A Griffiths (2016)
10.1016/j.plantsci.2017.05.003
High-biomass C4 grasses-Filling the yield gap.
J. Mullet (2017)
10.1111/pbi.12991
Transcriptome and metabolome reveal distinct carbon allocation patterns during internode sugar accumulation in different sorghum genotypes
Yin Li (2019)
10.1093/jxb/erx083
Increasing crop yield and resilience with trehalose 6-phosphate: targeting a feast–famine mechanism in cereals for better source–sink optimization
M. Paul (2017)
10.3389/fchem.2018.00026
Heat and Drought Stresses in Crops and Approaches for Their Mitigation
Mouna Lamaoui (2018)
10.1101/2020.02.15.950535
Defensive forwards: stress-responsive proteins in cell walls of crop plants
Liangjie Niu (2020)
10.1093/pcp/pcx072
Regulation of Gene Expression in the Remobilization of Carbon Reserves in Rice Stems During Grain Filling
Guan-qun Wang (2017)
10.1016/j.plgene.2020.100232
Comparative transcriptomics reveal insights into the drought response of the three Panicum species P. bisulcatum, P. laetum and P. turgidum
Peter Kotrade (2020)
10.1038/s41586-019-1679-0
Genetic strategies for improving crop yields
J. Bailey-Serres (2019)
10.3389/fpls.2017.00136
RNA-seq Analysis of Cold and Drought Responsive Transcriptomes of Zea mays ssp. mexicana L.
X. Lu (2017)
10.15666/aeer/1706_1397513988
GENETIC INHERITANCE OF GRAIN YIELD AND ITS RELATED TRAITS IN MAIZE (ZEA MAYS L.) UNDER WATER DEFICIT
M. Ramzan (2019)
10.1186/s12284-017-0189-7
Exploring traditional aus-type rice for metabolites conferring drought tolerance
Alberto Casartelli (2017)
10.3389/fpls.2017.00174
Enhancing Omics Research of Crop Responses to Drought under Field Conditions
S. Wu (2017)
10.1016/j.tplants.2015.10.009
Source-Sink Communication: Regulated by Hormone, Nutrient, and Stress Cross-Signaling.
S. Yu (2015)
10.1002/9781119312994.APR0637
Plant Desiccation Tolerance: A Survival Strategy with Exceptional Prospects for Climate‐Smart Agriculture
H. Hilhorst (2018)
10.1016/j.jplph.2018.10.022
Improving photosynthesis, plant productivity and abiotic stress tolerance - current trends and future perspectives.
B. Nowicka (2018)
10.1093/jxb/erw079
Cross-tolerance to biotic and abiotic stresses in plants: a focus on resistance to aphid infestation.
C. Foyer (2016)
10.1002/jsfa.10153
Differential Adaptation Strategies to Different Levels of Soil Water Deficit in Two Upland and Lowland Genotypes of Rice: A Physiological and Metabolic Approach.
Somayeh Abdirad (2019)
10.1038/s41598-018-31216-9
Ovary abortion is prevalent in diverse maize inbred lines and is under genetic control
Jeffery L Gustin (2018)
10.3390/AGRONOMY8080146
Plant Desiccation Tolerance and its Regulation in the Foliage of Resurrection “Flowering-Plant” Species
C. Blomstedt (2018)
10.3389/fpls.2018.01249
Using Biotechnology-Led Approaches to Uplift Cereal and Food Legume Yields in Dryland Environments
Sangam Lal Dwivedi (2018)
10.1007/s11033-019-04737-3
A study on optimization of pat gene expression cassette for maize transformation
E. Sivamani (2019)
Can Alterations in Other Starch Biosynthetic Enzymes Increase Yield ?
Jens Kossmann (2019)
10.3390/plants9030315
Characterization of Trehalose-6-phosphate Synthase and Trehalose-6-phosphate Phosphatase Genes and Analysis of its Differential Expression in Maize (Zea mays) Seedlings under Drought Stress
Phamela Acosta-Pérez (2020)
10.1177/1176934320910145
Delineation of the Crucial Evolutionary Amino Acid Sites in Trehalose-6-Phosphate Synthase From Higher Plants
Rong Wang (2020)
Overexpression of ca 1 pase decreases Rubisco abundance and grain yield in wheat 9 10
A. K. M. Lobo (2019)
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