Please confirm you are human (Sign Up for free to never see this)
← Back to Search
Lycopene-rich Products And Dietary Photoprotection.
W. Stahl, U. Heinrich, O. Aust, H. Tronnier, H. Sies
Published 2006 · Biology, Medicine
Save to my Library
Download PDFAnalyze on Scholarcy
Plant constituents such as carotenoids and flavonoids are involved in the light-protecting system in plants and contribute to the prevention of UV damage in humans. As micronutrients they are ingested with the diet and are distributed into light-exposed tissues where they provide systemic photoprotection. beta-Carotene is an endogenous photoprotector, and its efficacy to prevent UV-induced erythema formation has been demonstrated in intervention studies. Lycopene is the major carotenoid of the tomato and is a very efficient singlet oxygen quencher in the group of carotenoids. Following ingestion of lycopene or tomato-derived products rich in lycopene, photoprotective effects have been demonstrated. After 10-12 weeks of intervention a decrease in the sensitivity towards UV-induced erythema was observed in volunteers. Dietary carotenoids may contribute to life-long protection against harmful UV radiation.
This paper references
Lycopene is more bioavailable from tomato paste than from fresh tomatoes.
C. Gaertner (1997)
Carotenoids and carotenoids plus vitamin E protect against ultraviolet light-induced erythema in humans.
W. Stahl (2000)
The Beta-Carotene and Retinol Efficacy Trial: incidence of lung cancer and cardiovascular disease mortality during 6-year follow-up after stopping beta-carotene and retinol supplements.
G. Goodman (2004)
A clinical trial of the effects of oral beta-carotene on the responses of human skin to solar radiation.
M. Mathews-Roth (1972)
Obermueller-Jevic, UV light, beta-carotene and human skin-beneficial and potentially harmful effects, Arch
U.C.H.K. Biesalski (2001)
Antioxidant defense: vitamins
W. Stahl (1997)
A nonsaponfication method for the determination of carotenoids, retinoids, and tocopherols in solid human tissues, Cancer
Y.-M. Peng (1993)
Increased dermal carotenoid levels assessed by noninvasive reflection spectrophotometry correlate with serum levels in women ingesting Betatene.
W. Stahl (1998)
Photoprotective properties of skin melanin
J. Ortonne (2002)
Antioxidants in Photosynthesis and Human Nutrition
B. Demmig-Adams (2002)
The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers.
O. Heinonen (1994)
Introduction: The colorful, fascinating world of the carotenoids: important physiologic modulators
J. Olson (1995)
beta-Carotene: an unusual type of lipid antioxidant.
G. W. Burton (1984)
The Antioxidant and Biological Properties of the Carotenoids a
N. Krinsky (1998)
Ultraviolet light induced injury: Immunological and inflammatory effects
G. Clydesdale (2001)
UV-induced oxidative stress and photoaging.
J. Wenk (2001)
Cutaneous photodamage, oxidative stress, and topical antioxidant protection.
S. Pinnell (2003)
Lycopene: a biologically important carotenoid for humans?
W. Stahl (1996)
Effect of beta‐carotene supplementation on the human sunburn reaction
M. Garmyn (1995)
Effects of oral vitamin E and beta-carotene supplementation on ultraviolet radiation-induced oxidative stress in human skin.
F. Mcardle (2004)
Separation of beta-carotene and lycopene geometrical isomers in biological samples.
W. Stahl (1993)
Identification, quantification, and relative concentrations of carotenoids and their metabolites in human milk and serum.
F. Khachik (1997)
Factors Influencing the Uptake and Absorption of Carotenoids
A. Williams (1998)
Access of Medicaid recipients to outpatient care.
A. Kellermann (1994)
A nonsaponification method for the determination of carotenoids, retinoids, and tocopherols in solid human tissues.
Y. M. Peng (1993)
Ingold, b-Carotene: an unusual type of lipid antioxidant
W Burton (1984)
Supplementation with beta-carotene or a similar amount of mixed carotenoids protects humans from UV-induced erythema.
U. Heinrich (2003)
Antioxidant Defense: Vitamins E and C and Carotenoids
W. Stahl (1997)
43 COLIPA sun protection factor test method, The European Cosmetic Toiletry and Perfumery Association–COLIPA
Antioxidant activity of carotenoids.
W. Stahl (2003)
Dietary tomato paste protects against ultraviolet light-induced erythema in humans.
W. Stahl (2001)
Carotenoids in human buccal mucosa cells after 4 wk of supplementation with tomato juice or lycopene supplements.
I. Paetau (1999)
Supplementation with tomato-based products increases lycopene, phytofluene, and phytoene levels in human serum and protects against UV-light-induced erythema.
O. Aust (2005)
Singlet oxygen quenching by dietary carotenoids in a model membrane environment.
A. Cantrell (2003)
Molecular mechanisms of UV‐induced apoptosis
D. Kulms (2000)
Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial.
G. Omenn (1996)
Antioxidant and prooxidant properties of carotenoids.
A. Young (2001)
Sunburn and Apoptosis
J. Césarini (1997)
Systemic photoprotection Dietary intervention and therapy
H. Black (2001)
Lycopene as the most efficient biological carotenoid singlet oxygen quencher.
P. Di Mascio (1989)
Sunscreens: topical and systemic approaches for protection of human skin against harmful effects of solar radiation.
M. Pathak (1982)
Carotenoid supplementation reduces erythema in human skin after simulated solar radiation exposure.
J. Lee (2000)
M. Boniol (2007)
Photoprotection, in Dermatological Phototherapy and Photodiagnostic Methods
P. Wolf (2001)
[Sun and skin].
L. Andreassi (1966)
beta-Carotene interferes with ultraviolet light A-induced gene expression by multiple pathways.
K. Wertz (2005)
Systemic beta carotene plus topical UV-sunscreen are an optimal protection against harmful effects of natural UV-sunlight : results of the Berlin-Eilath study
H. Gollnick (1996)
Sunscreens: practical applications, in Sun Protection in Man
D Orentreich (2001)
UV light, beta-carotene and human skin--beneficial and potentially harmful effects.
H. Biesalski (2001)
Adams , III , Antioxidants in photosynthesis and human nutrition
W. W. (2001)
Nutritional protection against skin damage from sunlight.
H. Sies (2004)
Ultraviolet light induced injury: immunological and inflammatory effects, Immunol
G. J. Clydesdale (2001)
Sunscreens: practical applications, in Sun Protection in Man, ed
D. Orentreich (2001)
Sun and skin. Role of phototype and skin colour.
L. Andreassi (1999)
Sunscreens: practical applications
D. Orentreich (2001)
Sunburn and apoptosis in Skin Cancer and UV Radiation
P Cesarini (1997)
This paper is referenced by
A review of common tanning methods.
Michael Garone (2015)
TOMATO BY-PRODUCTS AS A SOURCE OF NATURAL ANTIOXIDANTS FOR PHARMACEUTICAL AND FOOD INDUSTRIES – A MINI-REVIEW
R. Stoica (2018)
Update on Photoprotection
Y. Gilabertea (2017)
The Inside‐Out Concept as Complement to the Use of Topical Sunscreen: The Case for Endogenous Skin Photoprotection from Sunlight by Natural Dietary Actives such as Tomato Carotenoids
J. Lévy (2011)
Solar radiation induced skin damage: Review of protective and preventive options
A. Svobodová (2010)
Tomato Consumption and Health: Emerging Benefits
B. Burton-Freeman (2011)
[Antioxidants in photoprotection: Do they really work?].
M. Gálvez (2010)
Whole Fruit Phytochemicals Combating Skin Damage and Carcinogenesis
Charlotte A. Mintie (2019)
The role of antioxidants in the chemistry of oxidative stress: A review.
A. M. Pisoschi (2015)
Beneficial effects and potential risks of tomato consumption for human health: An overview.
B. Salehi (2019)
United States Patent Hirschberg
Skin photoprotection and consumption of coffee and polyphenols in healthy middle‐aged Japanese females
Y. Fukushima (2015)
Skin cancer epidemic in a wireless world.
A. Logan (2011)
Supplementation of Flaxseed Oil Diminishes Skin Sensitivity and Improves Skin Barrier Function and Condition
K. Neukam (2010)
The Protective Role of Astaxanthin for UV-Induced Skin Deterioration in Healthy People—A Randomized, Double-Blind, Placebo-Controlled Trial
Naoki Ito (2018)
Chemoprevention of photocarcinogenesis by lycopene
A. Ascenso (2014)
Potential probiotic lactic acid bacterium Lactococcus lactis H61 contributing to high quality of life
Hiromi Kimoto-Nira (2018)
Singlet oxygen and natural substrates: functional polyunsaturated models for the photooxidative degradation of carotenoids
A. Griesbeck (2015)
Tangerine tomato carotenoids: Processing, structure, bioavailability and biological implications of consumption
J. Cooperstone (2014)
[Update on photoprotection].
Y. Gilaberte (2010)
Botanical Antioxidants for Protection Against Damage from Sunlight
M. Zaid (2009)
Nutritional Importance of Carotenoids and Their Effect on Liver Health: A Review
L. I. Elvira-Torales (2019)
Effects of ingesting milk fermented by Lactococcus lactis H61 on skin health in young women: a randomized double-blind study.
H. Kimoto-Nira (2014)
A REVIEW-HERBAL SUNSCREEN AGENTS ON SKIN PROTECTION
D. Anitha (2016)
Nutraceuticals for Antiaging
Bhanushree Gupta (2019)
Phytochemicals as protectors against ultraviolet radiation: versatility of effects and mechanisms.
A. Dinkova-Kostova (2008)
Understanding the Health Benefits of Tomato Products
Antioxidant Capacity and Antimutagenic Activity of Natural Oleoresin from Greenhouse Grown Tomatoes (Lycopersicon esculentum)
Eustolia Rodríguez-Muñoz (2009)
Characterization of Phytochemicals and Antioxidant Activities of Specialty Tomatoes
Qi Yuwei (2016)
Seven-day Green Tea Supplementation Revamps Gut Microbiome and Caecum/Skin Metabolome in Mice from Stress
E. S. Jung (2019)
Tomatoes protect against development of UV-induced keratinocyte carcinoma via metabolomic alterations
J. Cooperstone (2017)
Intervention with flaxseed and borage oil supplements modulates skin condition in women.
S. De Spirt (2009)See more