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Conjugated Polymer Microparticles For Selective Cancer Cell Image-guided Photothermal Therapy

Guangxue Feng, Jie Liu, Junlong Geng, Bin Liu

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We report conjugated polymers (CPs) microparticles (MPs) for selective cancer cell image-guided photothermal therapy. The CPMPs without surface functionalization can target MCF-7 cancer cells over NIH-3T3 normal cells, while nanoparticles need surface decoration to possess selectivity. Benefitting from large absorption, bright fluorescence, and efficient light-to-heat conversion of CPs, the fabricated MPs can selectively kill MCF-7 cells under NIR infrared laser irradiation.