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Pro-apoptotic And Pro-differentiation Induction By 8-quinolinecarboxaldehyde Selenosemicarbazone And Its Co(iii) Complex In Human Cancer Cell Lines

Nenad R. Filipović, Snežana Bjelogrlić, Gustavo Portalone, Sveva Pelliccia, Romano Silvestri, Olivera Klisurić, Milan Senćanski, Dalibor Stanković, Tamara R. Todorović, Christian D. Muller

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The ligand initiated reprogramming of cancer stem cells phenotype in AsPC-1 cells. The complex digested plasmid DNA which might be the cause of its cytotoxic activity.