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Controlling The Resolution And Duration Of Pulsatile Release From Injectable Magnetic ‘plum-pudding’ Nanocomposite Hydrogels

Danielle Maitland, Scott B. Campbell, Jenny Chen, Todd Hoare

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Injectable hydrogel nanocomposites with entrapped SPIONs, thermosensitive microgels, and model drugs generate heat when an alternating magnetic field is applied, causing the microgels to deswell and create pore space to promote enhanced drug release.