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Preparation And Evaluation Of PCL–PEG–PCL Polymeric Nanoparticles For Doxorubicin Delivery Against Breast Cancer

Linhua Zhang, Zhuo Chen, Hai Wang, Shengjie Wu, Kongyin Zhao, Hongfan Sun, Deling Kong, Chun Wang, Xigang Leng, Dunwan Zhu

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DOX-loaded polymeric NPs based on PCL–PEG–PCL triblock copolymers were successfully prepared and showed highly efficient targeting and accumulation in tumor via EPR effect. The prepared NPs would be a promising nanosized DDS for cancer therapy.