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Preparation And Evaluation Of Celecoxib Nanosuspensions For Bioavailability Enhancement

Jiali He, Yue Han, Gujun Xu, Lifang Yin, M. Ngandeu Neubi, Jianping Zhou, Yang Ding

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We prepare celecoxib nanosuspensions using TPGS as stabilizer via high speed shear as a pre-treatment step, followed by HPH method; and the solidification of fresh nanosuspension was carried out by freeze-drying.