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Nitrogen Doped Carbon Dots: Mechanism Investigation And Their Application For Label Free CA125 Analysis

Yuanyuan Liu, Liping Jiang, Bijun Li, Xinyue Fan, Wei Wang, Pingping Liu, Shenghao Xu, Xiliang Luo

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Nitrogen-doped CDs (N-CDs) were firstly prepared by using pear juice as the carbon source and ethanediamine as a nitrogen doping precursor with a microwave assisted pyrolysis technique. Based on the fluorescence recovery induced by competitive adsorption and desorption, a label-free “turn on” fluorescence assay with high sensitivity and selectivity was proposed for the analysis of CA125.