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Mannose-coated Polydiacetylene (PDA)-based Nanomicelles: Synthesis, Interaction With Concanavalin A And Application In The Water Solubilization And Delivery Of Hydrophobic Molecules

E. Romero-Ben, T. Mena Barragán, E. García de Dionisio, E. M. Sánchez-Fernández, J. M. Garcia Fernández, E. Guillén-Mancina, M. López-Lázaro, N. Khiar

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A shotgun-like approach allowing the synthesis of photopolymerized glycomicelles with enhanced affinity toward lectins and interesting abilities to solubilize and slowly liberate clinically relevant lipophilic drugs within cancer cells is presented.