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Direct Asymmetric Hydrogenation Of α-keto Acids By Using The Highly Efficient Chiral Spiro Iridium Catalysts

Pu-Cha Yan, Jian-Hua Xie, Xiang-Dong Zhang, Kang Chen, Yuan-Qiang Li, Qi-Lin Zhou, Da-Qing Che

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The Ir/SpiroPAP catalyzed direct asymmetric hydrogenation of α-keto acids under mild reaction conditions has been developed.