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Incorporation Of Native Antibodies And Fc-fusion Proteins On DNA Nanostructures Via A Modular Conjugation Strategy

Bas J. H. M. Rosier, Glenn A. O. Cremers, Wouter Engelen, Maarten Merkx, Luc Brunsveld, Tom F. A. de Greef

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A photocrosslinkable protein G adapter was used to site-specifically conjugate complex native proteins to oligonucleotides, allowing for efficient incorporation on DNA origami nanostructures.