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(+)-Catechin Inhibits Heart Mitochondrial Complex I And Nitric Oxide Synthase: Functional Consequences On Membrane Potential And Hydrogen Peroxide Production

Darío E. Iglesias, Silvina S. Bombicino, Alberto Boveris, Laura B. Valdez

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The aim was to study thein vitroeffect of nM to low μM concentration of (+)-catechin on the enzymatic activities of mitochondrial complex I and mtNOS, as well as the consequences on the membrane potential and H2O2production rate.