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Bacteria-assisted Biogreen Synthesis Of Radical Scavenging Exopolysaccharide-iron Complexes: An Oral Nano-sized Nutritional Supplement With High In Vivo Compatibility.

Seyyed Vahid Niknezhad, Ghasem Najafpour Darzi, S. Kianpour, S. Jafarzadeh, H. Mohammadi, Y. Ghasemi, R. Heidari, M. Shahbazi
Published 2019 · Materials Science, Medicine
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Microbial exopolysaccharides (EPSs) have recently served as an efficient substrate for the production of biocompatible metal nanoparticles (NPs) given their favorable stabilizing and reducing properties due to the presence of polyanionic functional groups in their structure. In the present work, Pantoea sp. BCCS 001 GH was used to produce EPS-stabilized biogenic Fe NPs as a complex through a novel biosynthesis reaction. Physicochemical characterization of the EPS-Fe complex was performed, indicating high thermal stability, desirable magnetic properties due to the uniform distribution of the Fe NPs with the average size of ∼10 nm and spherical shape within the EPS matrix. In addition, the in vivo toxicity of the EPS-stabilized Fe NPs was evaluated to investigate their potential for the treatment of iron deficiency anemia. Biological blood parameters and organ histology studies confirmed very high safety of the biosynthesized composite, making EPS-Fe a suitable candidate with an economical and environment friendly synthesis method for a wide spectrum of potential fields in medicine.
This paper references
10.1049/IET-NBT.2017.0199
Biosynthesis of xanthan gum-coated INPs by using Xanthomonas campestris
A. Ebrahiminezhad (2018)
10.1016/j.apjtm.2017.07.005
Production, characterization and biological activities of acidic exopolysaccharide from marine Bacillus amyloliquefaciens 3MS 2017.
Samah A El-Newary (2017)
10.1016/j.cis.2010.02.001
Biological synthesis of metal nanoparticles by microbes.
Kannan Badri Narayanan (2010)
10.1155/2012/750891
Current State-of-Art and New Trends on Lipid Nanoparticles (SLN and NLC) for Oral Drug Delivery
P. Severino (2012)
10.1016/j.ijbiomac.2017.05.118
Optimization, partial characterization and antioxidant activity of an exopolysaccharide from Lactobacillus plantarum KX041.
X. Wang (2017)
10.1016/j.micres.2012.04.002
Magnetotactic bacteria, magnetosomes and their application.
Lei Yan (2012)
10.1016/j.nano.2013.12.011
A nano-disperse ferritin-core mimetic that efficiently corrects anemia without luminal iron redox activity
Jonathan J Powell (2014)
10.1038/srep18435
Characterization and Biotechnological Potential Analysis of a New Exopolysaccharide from the Arctic Marine Bacterium Polaribacter sp. SM1127
Mei-Ling Sun (2015)
10.1007/S00217-010-1382-8
Chemical characterization and antioxidant activity of an exopolysaccharide fraction isolated from Bifidobacterium animalis RH
Rihua Xu (2011)
10.1111/j.1574-6976.2008.00116.x
Genetics and cell biology of magnetosome formation in magnetotactic bacteria.
Dirk Schueler (2008)
10.1016/j.colsurfb.2012.08.046
Preparation of novel magnetic fluorescent nanoparticles using amino acids.
A. Ebrahiminezhad (2013)
A PRELIMINARY REPORT ON THE ISOLATION AND IDENTIFICATION OF MAGNETOTACTIC BACTERIA FROM IRAN ENVIRONMENT
Forough Farzan (2010)
10.1007/s11051-012-0964-8
Synthesis optimization and characterization of chitosan-coated iron oxide nanoparticles produced for biomedical applications
Gozde Unsoy (2012)
10.1038/nnano.2012.3
Oral exposure to polystyrene nanoparticles affects iron absorption.
Gretchen J Mahler (2012)
10.1016/J.JPOWSOUR.2013.06.029
Electrochemical activity and stability of core–shell Fe2O3/Pt nanoparticles for methanol oxidation
Yanting Liu (2013)
10.1002/jobm.201600417
Physicochemical and biological characteristics of the nanostructured polysaccharide-iron hydrogel produced by microorganism Klebsiella oxytoca.
S. Kianpour (2017)
10.1371/journal.pone.0117383
Ferrous Sulfate Supplementation Causes Significant Gastrointestinal Side-Effects in Adults: A Systematic Review and Meta-Analysis
Zoe Tolkien (2015)
10.1016/j.ijbiomac.2018.06.157
Eexopolysaccharide production of Pantoea sp. BCCS 001 GH: Physical characterizations, emulsification, and antioxidant activities.
Seyyed Vahid Niknezhad (2018)
10.1016/J.POWTEC.2015.09.021
Biogenic synthesis of iron nanoparticles using Amaranthus dubius leaf extract as a reducing agent
Muthukumar Harshiny (2015)
10.1016/S0020-1693(00)90407-9
The structure, size and solution chemistry of a polysaccharide iron complex(Niferex)
Robert D. Bereman (1989)
10.1016/j.carbpol.2012.01.093
Fermentation optimization, characterization and bioactivity of exopolysaccharides from Funalia trogii.
Peixin He (2012)
10.1093/ajcn/59.2.492S
Anemia and iron-deficiency anemia: compilation of data on pregnancy outcome.
T. Scholl (1994)
10.1016/j.bbagen.2011.10.013
Regulation of iron transport and the role of transferrin.
Konstantinos Gkouvatsos (2012)
10.1039/C004967K
A bio-generated Fe(III)-binding exopolysaccharide used as new catalyst for phenol hydroxylation
F. Baldi (2010)
10.1111/j.1365-2672.2009.04302.x
Iron-binding characterization and polysaccharide production by Klebsiella oxytoca strain isolated from mine acid drainage
F. Baldi (2009)
10.1093/ndt/gfv268
Novel iron-containing phosphate binders and anemia treatment in CKD: oral iron intake revisited.
Takeshi Nakanishi (2016)
10.1016/S0031-3955(02)00087-1
Hematologic disorders of children in developing countries.
D. Weatherall (2002)
10.1185/03007995.2012.761599
Tolerability of different oral iron supplements: a systematic review
María Jesús Cancelo-Hidalgo (2013)
10.1002/btpr.2660
Characterization of biogenic Fe (III)‐binding exopolysaccharide nanoparticles produced by Ralstonia sp. SK03
S. Kianpour (2018)
10.1016/j.ijpharm.2013.08.070
A novel approach to oral iron delivery using ferrous sulphate loaded solid lipid nanoparticles.
M. G. Zariwala (2013)
10.1007/S12668-012-0046-5
Extracellular Biosynthesis of Silver Nanoparticles Using Fungi Penicillium diversum and Their Antimicrobial Activity Studies
Sharanabasava V. Ganachari (2012)
10.1063/1.2821757
In vitro studies on ultrasmall superparamagnetic iron oxide nanoparticles coated with gummic acid for T2 MRI contrast agent.
Ioannis Rabias (2007)
10.1016/S0002-9629(15)40626-3
Iron absorption and transport.
M. Conrad (1999)
10.1016/j.biopha.2017.10.166
Mitochondria protection as a mechanism underlying the hepatoprotective effects of glycine in cholestatic mice.
Reza Heidari (2018)
Preventing and controlling iron deficiency anaemia through primary health care: A guide for health administrators and programme managers
E. M. Demaeyer (1989)
10.1007/s00394-006-0637-4
Improved iron bioavailability in an oat-based beverage: the combined effect of citric acid addition, dephytinization and iron supplementation
Huanmei Zhang (2007)
10.1089/ARS.2016.6665
Oxidant Mechanisms in Renal Injury and Disease
B RatliffBrian (2016)
Exopolysaccharides from Pleurotus pulmonarius: Fermentation Optimization, Characterization and Antioxidant Activity
Shen Jin-wen (2013)
10.1021/jf403973j
Citric acid mediates the iron absorption from low molecular weight human milk fractions.
Ravindranadh Palika (2013)
10.1111/j.2042-7158.1990.tb07033.x
Nanoparticle uptake by the rat gastrointestinal mucosa: quantitation and particle size dependency.
P. Jani (1990)
10.1016/j.beha.2004.08.022
Diagnosis and management of iron-deficiency anaemia.
J. Cook (2005)
10.1007/s13346-011-0023-5
Chitosan-coated solid lipid nanoparticles enhance the oral absorption of insulin
Pedro Fonte (2011)
10.1016/j.ijbiomac.2009.04.014
Antioxidative activity of polysaccharide fractions isolated from Lycium barbarum Linnaeus.
C Y Lin (2009)
10.1016/j.carbpol.2005.04.019
Interactions between iron(III) and sucrose, dextran, or starch in complexes
Ekasith Somsook (2005)
10.1093/jn/136.7.1910
Serum iron curves can be used to estimate dietary iron bioavailability in humans.
Rana E. Conway (2006)
10.4103/2008-7802.193092
The Effects of Nanoparticles Containing Iron on Blood and Inflammatory Markers in Comparison to Ferrous Sulfate in Anemic Rats
Elaheh Honarkar Shafie (2016)
10.1016/S0271-5317(01)00313-X
Iron supplementation prevents the development of iron deficiency in rats with omeprazole-induced hypochlorhydria
Edemilson Cardoso da Conceição (2001)
10.1126/science.289.5484.1567
Extension of life-span with superoxide dismutase/catalase mimetics.
S. Melov (2000)
10.1093/jn/137.3.614
Synthesis, characterization, and bioavailability in rats of ferric phosphate nanoparticles.
F. Rohner (2007)
10.1016/J.CARBPOL.2010.01.005
Antioxidant activity of an exopolysaccharide purified from Lactococcus lactis subsp. lactis 12
Daodong Pan (2010)
10.1016/j.carbpol.2017.08.124
Characterization, antioxidant property and cytoprotection of exopolysaccharide-capped elemental selenium particles synthesized by Bacillus paralicheniformis SR14.
Yuanzhi Cheng (2017)
10.1182/blood-2003-03-0953
Effect of hepcidin on intestinal iron absorption in mice.
A. Laftah (2004)
10.1007/BF02976925
Protein drug oral delivery: The recent progress
H. J. Lee (2002)
10.1111/j.1574-6941.2001.tb00837.x
Gel sequestration of heavy metals by Klebsiella oxytoca isolated from iron mat.
F. Baldi (2001)



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