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Bioorthogonal Protein Labelling Enables The Study Of Antigen Processing Of Citrullinated And Carbamylated Auto-antigens

Tyrza van Leeuwen, Can Araman, Linda Pieper Pournara, Arieke S. B. Kampstra, Thomas Bakkum, Mikkel H. S. Marqvorsen, Clarissa R. Nascimento, G. J. Mirjam Groenewold, Willemijn van der Wulp, Marcel G. M. Camps, George M. C. Janssen, Peter A. van Veelen, Gerard J. P. van Westen, Antonius P. A. Janssen, Bogdan I. Florea, Herman S. Overkleeft, Ferry A. Ossendorp, René E. M. Toes, Sander I. van Kasteren

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Click handle-containing antigens can be used to study uptake, processing and presentation by immune cells.