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Consequences Of Vitamin D Receptor Gene Polymorphisms For Growth Inhibition Of Cultured Human Peripheral Blood Mononuclear Cells By 1,25‐dihydroxyvitamin D3

E. Colin, A. Weel, A. Uitterlinden, C. Buurman, J. Birkenhäger, H. Pols, J. V. van Leeuwen
Published 2000 · Biology, Medicine

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In the vitamin D receptor (VDR) gene a BsmI restriction fragment length polymorphism (RFLP) in intron 8 and a translational start‐site polymorphism, identified as a FokI RFLP, have been described. Crucial for a proper interpretation of these polymorphisms in association studies is the knowledge whether they have direct consequences for 1,25‐(OH)2D3 action at cellular level. The present study was designed to assess functional significance of the FokI and BsmI VDR gene polymorphisms in peripheral blood mononuclear cells (PBMC) with a natural occurring VDR genotype for cell growth inhibition by 1,25‐(OH)2D3.
This paper references
10.1006/BBRC.1997.7986
Vitamin D receptor gene polymorphisms: analysis of ligand binding and hormone responsiveness in cultured skin fibroblasts.
C. Gross (1998)
10.1210/JCEM.80.9.7673427
Genetic influences on bone density: physiological correlates of vitamin D receptor gene alleles in premenopausal women.
G. Howard (1995)
Functional evaluation of endogenous VDR alleles in human fibroblast cell lines: Relative contribution of F/f and L/s genotypes to 1,25 (OH) 2 D 3 -elicited VDR transactivation ability
L S Remus (1998)
10.1002/JBMR.5650100621
The BsmI vitamin D receptor restriction fragment length polymorphism (BB) predicts low bone density in premenopausal black and white women
J. Fleet (1995)
Lack of correlation between start codon polymorphism of the vitamin D receptor gene and bone mineral density in premenopausal French women
T. R. Eccleshall (1998)
Are vitamin D receptor polymorphisms associated with bone mineral density
G. S. Cooper (1996)
10.1093/JNCI/89.2.166
Association of prostate cancer risk with genetic polymorphisms in vitamin D receptor and androgen receptor.
S. Ingles (1997)
10.1016/S0140-6736(95)92019-6
Vitamin D receptor genotypes and bone mineral density
H. Kröger (1995)
10.1210/JCEM.83.3.4668-5
Genetic influences on bone density: physiological correlates of vitamin D receptor gene alleles in premenopausal women. Notification of genotype corrections.
G. Howard (1998)
10.1359/jbmr.1997.12.5.726
Quantification of Vitamin D Receptor mRNA by Competitive Polymerase Chain Reaction in PBMC: Lack of Correspondence with Common Allelic Variants
H. Mocharla (1997)
10.1038/367284A0
Prediction of bone density from vitamin D receptor alleles
N. Morrison (1994)
10.1359/jbmr.1998.13.11.1691
The Vitamin D Receptor Gene Start Codon Polymorphism: A Functional Analysis of FokI Variants
C. Gross (1998)
10.1002/JBMR.5650100620
Vitamin D receptor alleles and rates of bone loss: Influences of years since menopause and calcium intake
E. Krall (1995)
10.1359/jbmr.1997.12.6.915
A Vitamin D Receptor Gene Polymorphism in the Translation Initiation Codon: Effect on Protein Activity and Relation to Bone Mineral Density in Japanese Women
H. Arai (1997)
10.1016/0003-2697(77)90259-7
Improvements in the ethidium bromide method for direct fluorometric estimation of DNA and RNA in cell and tissue homogenates.
U. Karsten (1977)
Functional evaluation of endogenous VDR
L. S. Remus (1998)
10.1136/bmj.311.7009.874a
Vitamin D receptor genotype and bone mineral density
M. Peacock (1995)
10.3109/00365516809076979
The glomerular permeability determined by dextran clearance using Sephadex gel filtration.
C. Mogensen (1968)
Isolation of mononuclear cells and granulocytes from human blood.
A. Bøyum (1968)
A unique mutation in the vitamin D receptor gene in three Japanese patients with vitamin D-dependent rickets type II: utility of single-strand conformation polymorphism analysis for heterozygous carrier detection.
T. Saijo (1991)
10.1002/JBMR.5650100902
Vitamin D receptor gene polymorphisms do not predict bone turnover and bone mass in healthy premenopausal women
P. Garnero (1995)
Association of prostate cancer with vitamin D receptor gene polymorphism.
J. Taylor (1996)
10.1002/JBMR.5650110908
A large‐scale population‐based study of the association of vitamin D receptor gene polymorphisms with bone mineral density
A. Uitterlinden (1996)
10.1038/NM1295-1309
Vitamin D receptor genotypes in primary hyperparathyroidism
T. Carling (1995)
Vitamin D receptor genotype and bone mineral density.Lancet
S. ̈nen (1995)
10.1359/jbmr.1998.13.1.31
Lack of Correlation Between Start Codon Polymorphism of the Vitamin D Receptor Gene and Bone Mineral Density in Premenopausal French Women: The OFELY Study
T. R. Eccleshall (1998)
10.1172/JCI119530
Vitamin D receptor genotype is associated with radiographic osteoarthritis at the knee.
A. Uitterlinden (1997)
10.1172/JCI117568
Bone mineral density in relation to polymorphism at the vitamin D receptor gene locus.
F. G. Hustmyer (1994)
10.1359/jbmr.1997.12.8.1241
The Effect of Vitamin D Supplementation on the Bone Mineral Density of the Femoral Neck Is Associated with Vitamin D Receptor Genotype
W. Graafmans (1997)
10.1359/jbmr.1997.12.7.1049
The BsmI Vitamin D Receptor Restriction Fragment Length Polymorphism (bb) Influences the Effect of Calcium Intake on Bone Mineral Density
D. Kiel (1997)
10.1359/jbmr.1997.12.7.1043
The Vitamin D Receptor Start Codon Polymorphism (FokI) and Bone Mineral Density in Premenopausal American Black and White Women
S. Harris (1997)
Molecular characterization of polymorphic human vitamin D receptors that are associated with differences in bone mineral
P. W. Jurutka (1998)
10.1136/bmj.310.6991.1357
Influence of vitamin D receptor genotype on bone mineral density in postmenopausal women: a twin study in Britain
T. Spector (1995)
10.1002/JBMR.5650111203
Are vitamin D receptor polymorphisms associated with bone mineral density? A meta‐analysis
G. Cooper (1996)
10.1006/BBRC.1997.7239
Vitamin D receptor: no evidence for allele-specific mRNA stability in cells which are heterozygous for the Taq I restriction enzyme polymorphism.
W. Verbeek (1997)
10.1002/JBMR.5650111204
The presence of a polymorphism at the translation initiation site of the vitamin D receptor gene is associated with low bone mineral density in postmenopausal mexican‐American women
C. Gross (1996)
Isolation and analysis of cDNA encoding a naturally-occuring truncated form of the human vitamin D receptor
L. Sturzenbecker (1994)
The vitamin D receptor gene start codon polymorphism: a functional analysis
C. Gross (1998)
A novel polymorphism in the vitamin D receptor gene and bone mineral density: study of vitamin D receptor expression and function in COS-7 cells
K. Miyamoto (1996)
10.1128/MCB.13.6.3359
Sequences within the last intron function in RNA 3'-end formation in cultured cells.
D. Nešić (1993)



This paper is referenced by
10.1186/1742-6405-6-4
Is vitamin D deficiency involved in the immune reconstitution inflammatory syndrome?
A. Conesa-Botella (2009)
10.1158/1055-9965.EPI-06-0023
Polymorphisms of Vitamin D Receptor and Survival in Early-Stage Non–Small Cell Lung Cancer Patients
Wei Zhou (2006)
10.1111/cen3.12058
Vitamin D and multiple sclerosis in Asians and Caucasians: environmental and genetic aspects
M. Niino (2013)
Association of Vitamin D Receptor ( VDR ) Start Codon Fok-I Polymorphism with Chronic Myeloid Leukemia
Sheraz Fathi Saeed Algadal (2015)
The vitamin D receptor: biological and molecular properties
V. Martineti (2006)
10.1053/JHEP.2002.30084
Genetic association of vitamin D receptor polymorphisms with primary biliary cirrhosis and autoimmune hepatitis
A. Vogel (2002)
10.3109/1354750X.2015.1118535
Genetic variation in vitamin D receptor gene (Fok1:rs2228570) is associated with risk of coronary artery disease
Mohamed A Abu El Maaty (2016)
بررسی ارتباط بین واریانت تک نوکلئوتیدی rs2228570 از ژن VDR با اختلالات اسپرماتوژنز در مردان نابارور ایرانی
مهدی محبی (2016)
10.1002/ijc.23536
Dairy products, polymorphisms in the vitamin D receptor gene and colorectal adenoma recurrence
R. Hubner (2008)
10.1016/S0923-1811(02)00073-7
Polymorphisms of vitamin D receptor gene in Japanese patients with psoriasis vulgaris.
H. Saeki (2002)
10.1038/s41598-017-08621-7
Vitamin D Receptor Gene Polymorphisms Modify Cardiometabolic Response to Vitamin D Supplementation in T2DM Patients
N. Aldaghri (2017)
Chlamydia trachomatis: Clinical, bacterial, and host aspects of a silent love bug
E. Lanjouw (2017)
10.1002/mds.24016
25‐hydroxyvitamin D, vitamin D receptor gene polymorphisms, and severity of Parkinson's disease
M. Suzuki (2012)
10.1016/B978-0-12-381978-9.10097-6
Psoriasis and Other Skin Diseases
J. Reichrath (2011)
10.1007/s00223-002-0032-y
A Poly Adenosine Repeat in the Human Vitamin D Receptor Gene is Associated with Bone Mineral Density in Young Swedish Women
E. Grundberg (2002)
10.1207/s15327914nc5501_5
Vitamin D Receptor Gene Polymorphisms, Dietary Promotion of Insulin Resistance, and Colon and Rectal Cancer
M. Murtaugh (2006)
10.1371/JOURNAL.PMED.0040103
A Prospective Study of Plasma Vitamin D Metabolites, Vitamin D Receptor Polymorphisms, and Prostate Cancer
H. Li (2007)
10.1111/j.1600-0714.2012.01164.x
Vitamin D receptor, CYP27B1 and CYP24A1 genes polymorphisms association with oral cancer risk and survival.
K. Zeljic (2012)
10.1038/sj.bjc.6605414
Vitamin D receptor polymorphisms and prognosis of patients with epithelial ovarian cancer
S. Tamez (2009)
Immunomodulacyjne działanie witaminy D The immunomodulatory role of Vitamin D
M. Myszka (2014)
10.1016/j.jhep.2009.01.015
Vitamin D receptor polymorphisms are associated with increased susceptibility to primary biliary cirrhosis in Japanese and Italian populations.
A. Tanaka (2009)
10.2217/14622416.9.6.733
Pharmacogenetics of bone treatments: the VDR and ERalpha gene story.
F. Massart (2008)
10.1080/01635580701745319
The Interaction of Genetic Polymorphisms With Lifestyle Factors: Implications for the Dietary Prevention of Prostate Cancer
E. C. Nelson (2008)
Importancia del calcio en patología endocrinológica
E. B. Guadarrama (2001)
Molecular analysis of vitamin D receptor gene polymorphisms rs 2228570 ( FokI ) and rs 1544410 ( BsmI ) in patients with Behcet ’ s Disease
Hamidreza Khodadadi (2013)
10.4161/derm.16519
Vitamin D receptor (VDR) polymorphisms and skin cancer
N. Denzer (2011)
10.1016/B978-012098652-1.50174-8
Chapter 72 – Genetic Determinants of Bone Mass and Osteoporotic Fracture
S. Ralston (2002)
10.1080/01635581.2001.9680606
Molecular targets for nutrients involved with cancer prevention.
J. Milner (2001)
10.1152/ajprenal.1999.277.2.F157
Vitamin D.
A. Brown (1999)
10.1086/527488
Vitamin D receptor polymorphisms and the risk of acute lower respiratory tract infection in early childhood.
D. Roth (2008)
10.1016/j.bjoms.2020.08.101
Relationship of Vitamin D and Bsml variant with Temporomandibular Diseases in Turkish population
S. Yıldız (2020)
10.1093/carcin/bgp103
Review and meta-analysis on vitamin D receptor polymorphisms and cancer risk.
S. Raimondi (2009)
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