Online citations, reference lists, and bibliographies.
← Back to Search

Cutaneous Gene Transfer For Skin And Systemic Diseases

P. Khavari, O. Rollman, A. Vahlquist
Published 2002 · Medicine

Save to my Library
Download PDF
Analyze on Scholarcy Visualize in Litmaps
Share
Reduce the time it takes to create your bibliography by a factor of 10 by using the world’s favourite reference manager
Time to take this seriously.
Get Citationsy
This article is partially based on the findings presented at a symposium on Cutaneous Gene Therapy, held in Uppsala, September 2001, and abstracted in Acta Derm Venereol 81: 227–239.
This paper references
10.1126/SCIENCE.3629250
Expression of an exogenous growth hormone gene by transplantable human epidermal cells.
J. Morgan (1987)
10.1073/PNAS.86.22.8803
Systemic distribution of apolipoprotein E secreted by grafts of epidermal keratinocytes: implications for epidermal function and gene therapy.
E. Fenjves (1989)
10.1016/0022-4804(92)90278-8
Healing of partial thickness porcine skin wounds in a liquid environment.
K. Breuing (1992)
10.1038/NG0293-180
Towards gene therapy for haemophilia B using primary human keratinocytes
A. J. Gerrard (1993)
10.1089/HUM.1994.5.10-1241
Systemic delivery of secreted protein by grafts of epidermal keratinocytes: prospects for keratinocyte gene therapy.
E. Fenjves (1994)
10.1073/PNAS.91.20.9307
Genetically modified keratinocytes transplanted to wounds reconstitute the epidermis.
P. Vogt (1994)
10.1073/PNAS.91.25.12188
In vivo transfer and expression of a human epidermal growth factor gene accelerates wound repair.
C. Andree (1994)
10.1038/NM0795-705
The feasibility of targeted selective gene therapy of the hair follicle
L. Li (1995)
10.1111/1523-1747.EP12325550
Genetically modified human epidermis overexpressing PDGF-A directs the development of a cellular and vascular connective tissue stroma when transplanted to athymic mice--implications for the use of genetically modified keratinocytes to modulate dermal regeneration.
S. Eming (1995)
10.1111/1523-1747.EP12612734
Sustained production of human transferrin by transduced fibroblasts implanted into athymic mice: a model for somatic gene therapy.
M. Petersen (1995)
10.1038/NM1196-1263
Corrective gene transfer in the human skin disorder lamellar ichthyosis
K. Choate (1996)
10.1038/icb.1996.19
Control of scarring in adult wounds using antisense transforming growth factor‐β1 oligodeoxynucleotides
BYUNG‐MIN CHOI (1996)
10.1172/JCI118750
Expression of naked DNA in human, pig, and mouse skin.
U. Hengge (1996)
10.1089/HUM.1996.7.18-2247
Transglutaminase 1 delivery to lamellar ichthyosis keratinocytes.
K. Choate (1996)
10.1089/HUM.1997.8.14-1659
Direct cutaneous gene delivery in a human genetic skin disease.
K. Choate (1997)
10.1007/s001090050172
Targeted gene conversion in a mammalian CD34+-enriched cell population using a chimeric RNA/DNA oligonucleotide
Y. Xiang (1997)
10.1001/ARCHDERM.1997.03890430146031
Skin Barrier: Principles of Percutaneous Absorption
R. Potts (1997)
10.1038/41917
Vaccination onto bare skin
D. Tang (1997)
10.1093/HMG/6.6.927
A model of corrective gene transfer in X-linked ichthyosis.
R. A. Freiberg (1997)
10.1111/1523-1747.EP12286471
Transfection with aFGF cDNA improves wound healing.
L. Sun (1997)
10.1016/S0039-6060(97)90105-7
Diabetes-impaired healing and reduced wound nitric oxide synthesis: a possible pathophysiologic correlation.
M. Schäffer (1997)
10.1016/S1357-4310(97)01143-X
Therapeutic gene delivery to the skin.
P. Khavari (1997)
10.1111/1523-1747.EP12319188
Reduced expression of PDGF and PDGF receptors during impaired wound healing.
H. D. Beer (1997)
10.1073/PNAS.94.1.219
Transgenic studies with a keratin promoter-driven growth hormone transgene: prospects for gene therapy.
X. Wang (1997)
Paracrine stimulation of keratinocytes in vitro and continuous delivery of epidermal growth factor to wounds in vivo by genetically modified fibroblasts transfected with a novel chimeric construct.
F. Rosenthal (1997)
10.1172/JCI2067
Reversal of impaired wound repair in iNOS-deficient mice by topical adenoviral-mediated iNOS gene transfer.
K. Yamasaki (1998)
10.1089/HUM.1998.9.4-529
Genetically modified human keratinocytes overexpressing PDGF-A enhance the performance of a composite skin graft.
S. Eming (1998)
10.1097/00006534-199811000-00034
Locally Administered Vascular Endothelial Growth Factor cDNA Increases Survival of Ischemic Experimental Skin Flaps
P. Taub (1998)
10.1128/JVI.73.9.7376-7380.1999
High-Fidelity Correction of Mutations at Multiple Chromosomal Positions by Adeno-Associated Virus Vectors
Naoki Inoue (1999)
10.1002/(SICI)1521-2254(199901/02)1:1<31::AID-JGM3>3.0.CO;2-T
Selective uptake and sustained expression of AAV vectors following subcutaneous delivery
B. A. Donahue (1999)
10.1089/TEN.1999.5.563
Cultured epidermal keratinocytes on a microspherical transport system are feasible to reconstitute the epidermis in full-thickness wounds.
M. Voigt (1999)
10.1038/12856
Immunization via hair follicles by topical application of naked DNA to normal skin
H. Fan (1999)
10.1093/NAR/27.5.1323
Targeted gene repair directed by the chimeric RNA/DNA oligonucleotide in a mammalian cell-free extract.
A. Cole-Strauss (1999)
10.1038/sj.gt.3300956
In vivo transduction of mouse epidermis with recombinant retroviral vectors: implications for cutaneous gene therapy
S. Ghazizadeh (1999)
10.1046/J.1523-1747.1999.00705.X
Adenoviral-mediated overexpression of platelet-derived growth factor-B corrects ischemic impaired wound healing.
K. Liechty (1999)
10.1046/J.1523-1747.1999.00549.X
Proliferation and mitogenic response to PDGF-BB of fibroblasts isolated from chronic venous leg ulcers is ulcer-age dependent.
M. Ågren (1999)
10.1038/sj.gt.3300809
BP180 gene delivery in junctional epidermolysis bullosa
C. S. Seitz (1999)
Genetic immunization via hair follicles after topical application of naked DNA to normal skin
H Fan (1999)
Ichthyosis: An inborn dryness of the skin
A. Vahlquist (1999)
10.1089/104303400750035807
The genodermatoses: candidate diseases for gene therapy.
J. Uitto (2000)
10.1089/104303400750035816
Genetic correction of inherited epidermal disorders.
P. Khavari (2000)
10.1089/104303400750035834
Fibroblasts and dermal gene therapy: a minireview.
G. Krueger (2000)
10.1073/PNAS.250380097
Epidermal stem cells: properties, markers, and location.
R. Lavker (2000)
10.1006/JSRE.2000.5912
Collagen-embedded platelet-derived growth factor DNA plasmid promotes wound healing in a dermal ulcer model.
J. W. Tyrone (2000)
10.1038/74480
Efficient delivery of transgenes to human hair follicle progenitor cells using topical lipoplex
A. Domashenko (2000)
10.1038/sj.gt.3301293
Transcriptional targeting of adenoviral gene delivery into migrating wound keratinocytes using FiRE, a growth factor-inducible regulatory element
P. Jaakkola (2000)
10.1089/104303400750001444
Tissue repair with a therapeutic transcription factor.
M. Bryant (2000)
10.1089/104303400750035843
Regulated cutaneous gene delivery: the skin as a bioreactor.
T. Cao (2000)
10.1046/j.1524-475x.2000.00117.x
Boosting epidermal growth factor receptor expression by gene gun transfection stimulates epidermal growth in vivo
L. Nanney (2000)
10.1016/S1040-0486(00)90017-6
Strategies for cutaneous gene therapy
P. Robbins (2000)
10.1046/j.1524-475x.2000.00494.x
Comparison and evaluation of gene therapy and epigenetic approaches for wound healing
Kenneth R. Cutroneo (2000)
Lentiviral vectors: progress and potential.
Lever Am (2000)
Lentiviral vectors: progress and potential.
A. Lever (2000)
10.3892/IJMM.6.4.391
Matrix metalloproteinases in wound repair (review).
L. Ravanti (2000)
10.1006/MTHE.2000.0107
Efficient nonviral cutaneous transfection.
J. Glasspool-Malone (2000)
10.1046/J.1523-1747.2000.00143.X
Intercellular adhesion molecule-1 suppression in skin by topical delivery of anti-sense oligonucleotides.
R. Mehta (2000)
Intercellular adhesion molecule-1 suppression in skin by topical delivery of antisense oligonucleotides
RC Mehta (2000)
10.1073/pnas.091484998
In vivo restoration of laminin 5 β3 expression and function in junctional epidermolysis bullosa
Paul B. Robbins (2001)
10.1089/107632701753337708
Plasmid gene delivery to human keratinocytes through a fibrin-mediated transfection system.
C. Andree (2001)
10.1080/000155501317208282
Does antisense make sense in dermatology?
P. V. van Erp (2001)
10.1089/10430340152480276
Sustainable systemic delivery via a single injection of lentivirus into human skin tissue.
S. Baek (2001)
10.1038/sj.gt.3301589
Therapeutic success and efficacy of nonviral liposomal cDNA gene transfer to the skin in vivo is dose dependent
M. Jeschke (2001)
10.1089/104303401750061212
Interleukin 12 gene transfer into skin distant from the tumor site elicits antimetastatic effects equivalent to local gene transfer.
K. Oshikawa (2001)
10.1016/S1471-4914(01)01965-7
Ribozyme gene therapy: applications for molecular medicine.
A. Lewin (2001)
10.1159/000056387
Coordinate Regulation of Epidermal Differentiation and Barrier Homeostasis
P. Elias (2001)
10.1097/00000637-200105000-00016
Treatment of Ischemic Wounds Using Cultured Dermal Fibroblasts Transduced Retrovirally With PDGF-B and VEGF121 Genes
A. Breitbart (2001)
10.1046/j.1365-2230.2001.00819.x
Keratinocyte adhesion and the missing link: from Dowling–Meara to Hay–WellsSt John's Hospital Dermatological Society Annual Oration 2000
J. McGrath (2001)
10.1016/S0163-7258(01)00133-4
Antisense oligonucleotides in cutaneous therapy.
C. Wraight (2001)
10.1046/j.1365-2796.2001.00808.x
Suicide gene therapy: possible applications in haematopoietic disorders
M. Dilber (2001)
10.1006/MTHE.2000.0257
Cutaneous transfection and immune responses to intradermal nucleic acid vaccination are significantly enhanced by in vivo electropermeabilization.
J. Drabick (2001)
Human keratinocytes transduced with the PDGF receptor beta gene renders reconstructed skin hyperproliferative upon ligand stimulation
O Rollman (2001)
Ribozyme gene therapy for keratin disorders
A Terron (2001)



This paper is referenced by
10.1038/s41598-020-79785-y
Downregulation of CR6-interacting factor 1 suppresses keloid fibroblast growth via the TGF-β/Smad signaling pathway
Harsha Nagar (2021)
10.4103/ijd.ijd_323_20
Gene Therapy and its Application in Dermatology
Tanusree Sarkar (2020)
10.1080/21678707.2020.1857724
Advances in understanding of Netherton syndrome and therapeutic implications
E. Petrova (2020)
10.5772/INTECHOPEN.85646
Burn Shock and Resuscitation: Many Priorities, One Goal
John Sojka (2019)
10.1007/978-3-319-78957-6_2
Gene Therapy in Skin and Wound Healing
K. Nuutila (2018)
10.1016/j.addr.2018.06.019
Re-epithelialization of adult skin wounds: Cellular mechanisms and therapeutic strategies.
P. Rousselle (2018)
10.14228/JPR.V4I1.217
APPLICATION OF ALLO MESENCHYMAL STEM CELLS ON CHRONIC BURN WOUND: CASE SERIES REPORT
A. Wardhana (2018)
10.1007/s40257-017-0313-x
Inherited Nonsyndromic Ichthyoses: An Update on Pathophysiology, Diagnosis and Treatment
A. Vahlquist (2017)
83 Thermal Assisted In Vivo Gene Electrotransfer
Amy Donate (2017)
10.24198/JF.V15I2.12908
Teknologi Induced Pluripotent Stem Cell (IPSC) Berbasis Metode 3D Hanging Drop Sebagai Terapi Genodermatosis Generasi Baru
Doni Dermawan (2017)
Gene therapy : Its applications in dermatology
D. Shaaban (2017)
10.1089/WOUND.2015.0658
Targeting Microtubules for Wound Repair.
Rabab A Charafeddine (2016)
10.2174/1566523216666160331125810
Thermal Assisted In Vivo Gene Electrotransfer.
Amy Donate (2016)
10.1111/exd.12666
Therapies for inherited skin fragility disorders
C. Has (2015)
10.17795/JSSC30351
Regenerative Medicine: Novel Approach in Burn Wound Healing
S. Zare (2015)
10.1016/j.jconrel.2014.01.006
Topical delivery of siRNA into skin using SPACE-peptide carriers.
M. Chen (2014)
10.1201/b18002-52
Cutaneous Cell- and Gene-Based Therapies for Inherited and Acquired Skin Disorders
J. C. Chamcheu (2014)
10.1002/jps.24068
A comprehensive review of advanced biopolymeric wound healing systems.
N. Mayet (2014)
10.1101/cshperspect.a015149
Gene therapy for skin diseases.
E. Gorell (2014)
10.1016/B978-0-12-409503-8.00006-8
Chapter 6 – Stem Cell Niches
D. Jones (2014)
10.1016/j.jconrel.2012.12.030
Gene silencing following siRNA delivery to skin via coated steel microneedles: In vitro and in vivo proof-of-concept.
Rosalind H.E. Chong (2013)
10.1371/journal.pone.0073423
Topical Gene Electrotransfer to the Epidermis of Hairless Guinea Pig by Non-Invasive Multielectrode Array
S. Guo (2013)
10.1016/B978-0-12-385942-6.00007-X
Chapter 7 – Stem Cell Niches
D. Jones (2013)
10.2174/1874382601003010043
Inflammatory and Angiogenic Abnormalities in Diabetic Wound Healing: Role of Neuropeptides and Therapeutic Perspectives
Ana Tellechea (2012)
10.1111/j.1600-0625.2011.01436.x
Lentiviral vectors for cutaneous RNA managing
Maria Nascimento Primo (2012)
10.1007/s12263-012-0320-8
Genetic and environmental influences on nutrient intake
J. Liu (2012)
10.1007/978-3-7091-0348-7_21
Treatment of burns — established and novel technology
L. Branski (2012)
10.1111/j.1600-0625.2012.01534.x
Progress towards genetic and pharmacological therapies for keratin genodermatoses: current perspective and future promise
J. Chamcheu (2012)
10.1016/j.biomaterials.2012.06.065
Drawing lithography for microneedles: a review of fundamentals and biomedical applications.
K. Lee (2012)
10.1089/hum.2011.211
Inhibition of CD44 gene expression in human skin models, using self-delivery short interfering RNA administered by dissolvable microneedle arrays.
M. F. Lara (2012)
CHARACTERIZATION OF IMMUNE-MODULATORY MIRNAS AND THEIR ROLE IN INFLAMMATORY SKIN DISEASE
F. Ciências (2011)
10.1089/pho.2010.2769
Minimally invasive automated de-epithelization by precise ArF excimer laser ablation.
M. Jadraque (2011)
See more
Semantic Scholar Logo Some data provided by SemanticScholar