Online citations, reference lists, and bibliographies.
Please confirm you are human
(Sign Up for free to never see this)
← Back to Search

Mesothelioma In South Africa, 1976-84: Incidence And Case Characteristics.

A. Zwi, G. Reid, S. Landau, D. Kielkowski, P. Sitas, M. Becklake
Published 1989 · Medicine

Save to my Library
Download PDF
Analyze on Scholarcy
Share
Malignant mesothelioma is a rare tumour known to be associated with prior exposure to asbestos. Previous studies have described the occupational and clinical features of cases of mesothelioma in the Republic of South Africa (RSA) but none has set out to determine incidence of this disease. To estimate incidence, a case register was compiled for 1976-84 by contacting all medical practitioners and institutions likely to have seen cases of mesothelioma in this period; demographic, diagnostic and exposure details were sought. Cases were accepted if they provided evidence of histological diagnosis of mesothelioma. Fifty-two per cent of 1347 cases identified were in whites, 31% in blacks, 16% in coloureds and 1% in Asians. Seventy-three per cent of cases occurred in males. The majority of whites were aged 51-70 years, while the majority in other race groups were aged 41-60 years. The ratio of only pleural to only peritoneal mesothelioma was 11:1, although there were marked differences by race. Eighty-five per cent of males with exposure information available had prior exposure to asbestos, mostly occupational. A similar proportion of women had contact with asbestos but mostly through other types of exposure. Standardized incidence rates per million population aged 15 years and over were calculated for sex-race subgroups and were highest in white males (32.9 per million per year, 95% Cl 22.7-46.4), coloured males (24.8 per million per year, 95% Cl 16.2-36.9) and coloured females (13.9 per million per year, 95% Cl 7.7-23.5). These incidence rates are amongst the highest ever reported for a national population. Age-specific standardized incidence rates were highest in white males (over 100 per million per year in men over 55 years). Reasons for the differing rates by population group are likely to include differential access to health services. More rigorous control of asbestos exposure in the RSA is recommended.



This paper is referenced by
10.1136/oem.57.8.563
Risk of mesothelioma from exposure to crocidolite asbestos: a 1995 update of a South African mortality study
D. Kielkowski (2000)
10.1136/oem.51.12.804
Malignant mesothelioma: attributable risk of asbestos exposure.
R. Spirtas (1994)
10.1002/(SICI)1097-0274(199903)35:3<213::AID-AJIM1>3.0.CO;2-R
Case-control study of mesothelioma in South Africa.
D. Rees (1999)
10.1144/jgs.157.4.851
Amphibole asbestos in Africa and Australia: geology, health hazard and mining legacy
W. Gibbons (2000)
10.1179/oeh.2003.9.3.194
Scientific Controversy and Asbestos: Making Disease Invisible
L. Braun (2003)
10.1002/AJIM.4700200309
Occupational asbestos exposure and mesothelioma risk in Los Angeles County: application of an occupational hazard survey job-exposure matrix.
C. Cicioni (1991)
10.1136/oem.47.11.775
Trends and geographical patterns of pleural mesotheliomas in the Netherlands 1970-87.
J. Meijers (1990)
Worker and community health impacts related to mining internationally: a rapid review of the literature
Carolyn Stephens (2001)
10.1002/9780470025079.CHAP49.PUB2
Pleura and Peritoneum
M. Sheaff (2007)
10.1097/PAS.0000000000001418
Malignant Diffuse Mesothelioma in Women
E. Pavlisko (2019)
10.1007/3-540-31040-1_40
Epidemiology and Etiology of Mesothelioma
S. Papiris (2006)
10.3816/CLC.2009.n.014
Malignant pleural mesothelioma: medical treatment update.
D. Vorobiof (2009)
10.1002/AJIM.4700200507
The incidence of malignant mesothelioma in Australia 1982-1988.
J. Leigh (1991)
10.1002/AJIM.4700240203
Asbestos-related mesothelioma in Monfalcone, Italy.
C. Bianchi (1993)
Mesothelioma incidence and mortality in South Africa from 2003 to 2013
Kasongo Michel Muteba (2018)
MESOTHELIOMA IN ·SOUTH AFRICA
Dayid Rees (2008)
10.1016/J.YRTPH.2007.09.013
South African experience with asbestos related environmental mesothelioma: is asbestos fiber type important?
Neil White (2008)
10.1111/J.1445-5994.1993.TB00532.X
Clinical aspects of malignant mesothelioma in Australia.
T. Driscoll (1993)
10.1016/S0013-9351(05)80237-3
Asbestos-related hazards in developing countries.
B. Levy (1992)
10.3402/gha.v6i0.19410
Compensation for environmental asbestos-related diseases in South Africa: a neglected issue
N. Ndlovu (2013)
10.1177/030089169608200603
Malignant Mesothelioma in Rome, Italy 1980-1995. A Retrospective Study of 79 Patients
V. Ascoli (1996)
10.1016/S1010-7940(03)00376-2
Treatment of mesothelioma in Bloemfontein, South Africa.
W. de Vries (2003)
What is the price of 80 kg's : the failure of the detection of, and compensation for, asbestos-related disease : social exclusion in Sekhukhuneland.
J. Roberts (2000)
10.1136/thx.48.3.269
Malignant mesothelioma in women.
A. Dawson (1993)
10.1002/IJC.2910600627
Trends in incidence of pleural mesothelioma in the Rotterdam area.
R. Damhuis (1995)
10.1136/oem.2010.062182
Trends in mesothelioma mortality rates in South Africa: 1995–2007
D. Kielkowski (2011)
10.5772/47974
Mineralogy and Malignant Mesothelioma: The South African Experience
J. I. Phillips (2012)
10.1016/0959-8049(93)90024-A
Malignant mesothelioma in the Rotterdam area, 1987-1989.
R. Damhuis (1993)
10.1002/AJIM.10098
Estimation of the incidence of pleural mesothelioma according to death certificates in France.
Y. Iwatsubo (2002)
Occupational carcinogens assessing the environmental burden of disease at national and local levels
T. Driscoll (2004)
10.1002/AJIM.4700260107
Pleural mesothelioma: a descriptive analysis based on a case-control study and mortality data in Ile de France, 1987-1990.
Y. Iwatsubo (1994)
10.1016/J.LUNGCAN.2004.04.007
Asbestos and mesothelioma in South Africa.
R. Abratt (2004)
See more
Semantic Scholar Logo Some data provided by SemanticScholar