Online citations, reference lists, and bibliographies.
Please confirm you are human
(Sign Up for free to never see this)
← Back to Search

Hyperexcitable Blink Reflex Preceding The Diagnosis Of Neuroblastoma.

Mohamed Ramadan, Bonny L. Whalen, K. De Santes
Published 2004 · Medicine

Save to my Library
Download PDF
Analyze on Scholarcy
The diagnosis of neuroblastoma is sometimes preceded by development of a paraneoplastic syndrome, most commonly opsoclonus-myoclonus-ataxia (OMA). The authors describe a patient who developed a hyperexcitable blink reflex, without symptoms of OMA, prior to his oncologic diagnosis. The authors believe this may represent a distinct paraneoplastic process caused by increased dopaminergic stimulation of the blink reflex and suggest that children manifesting an unexplained hyperexcitable blink reflex should be screened for occult neuroblastoma.
This paper references
Focal motor seizures with secondary generalization arising in the cerebellum. Case report and review of the literature.
A. H. Mesiwala (2002)
[Hyperexcitability of the blink reflex in a child with opsoclonus-myoclonus syndrome].
Y. Maeoka (1998)
Acute migraine headache: Possible sensitization of neurons in the spinal trigeminal nucleus?
H. Kaube (2002)
Opsoclonus-myoclonus-ataxia syndrome in neuroblastoma: clinical outcome and antineuronal antibodies-a report from the Children's Cancer Group Study.
E. Rudnick (2001)
Excessive blinking in childhood: a prospective evaluation of 99 children.
D. Coats (2001)
Behaviors mimicking seizures in institutionalized individuals with multiple disabilities and epilepsy: a video-EEG study
J. Detoledo (2002)
Increased brainstem excitability in stiff-person syndrome
F. M. Molloy (2002)
Differential effects of direct and indirect dopamine agonists on eye blink rate in cynomolgus monkeys.
M. Kleven (1996)
Blink rate in children with attention-deficit-hyperactivity disorder
R. Caplan (1996)
Blink rates and disorders of movement
C. Karson (1984)
Antineuronal antibodies in patients with neuroblastoma and paraneoplastic opsoclonus-myoclonus.
N. L. Antunes (2000)
Pharmacodynamics of ziprasidone in children and adolescents: impact on dopamine transmission.
F. Sallee (2003)
Blink reflex abnormalities in Tourette syndrome
R. Raffaele (2004)
Spontaneous Blink Rates Correlate with Dopamine Levels in the Caudate Nucleus of MPTP-Treated Monkeys
J. Taylor (1999)

This paper is referenced by
Semantic Scholar Logo Some data provided by SemanticScholar