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Archaeosomes As Means Of Nano-drug Delivery

E. Moghimipour, M. Kargar, S. Handali
Published 2014 · Biology

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Archaeosomes are a novel generation of liposomes that are made from polar ether lipids extracted from the Archaea. They have higher stabilities in acidic or alkaline pH, bile salts, high temperatures and against phospholipase, oxidation, chemical and enzymatic hydrolysis in comparison with conventional liposomes. Ether links are more stable than ester links. The ability of Archaea to adapt their membrane lipid compositions to harsh environments has resulted in archaeal lipids to be considered for the development of nano-drug delivery capable of overcoming the biophysical, biological and biomedical barriers that the body displays towards gene, drug and vaccine therapies. Archaeosomes are prepared from various type of Archaea which show high adjuvant activity and can promote humoral and cell-mediated immune responses. In-vitro and in-vivo studies indicate that archaeosomes are safe and can be used in biotechnology applications such as drug, gene and vaccine delivery.
This paper references
Nanoparticle Delivery Systems in Cancer Vaccines
Yogita Krishnamachari (2010)
Reporter gene-expressing bone marrow-derived stromal cells are immune-tolerated following implantation in the central nervous system of syngeneic immunocompetent mice
Irene Bergwerf (2009)
Effects of pH and temperature on the composition of polar lipids in Thermoplasma acidophilum HO-62.
H. Shimada (2008)
Review of novel particulate antigen delivery systems with special focus on treatment of type I allergy.
I. Schoell (2005)
Archaeosomes based on novel synthetic tetraether-type lipids for the development of oral delivery systems.
T. Benvegnu (2005)
NKT Cells in Sepsis
Briana Leung (2010)
Archaea and Their Potential Role in Human Disease
P. Eckburg (2003)
Physiological roles of trehalose in bacteria and yeasts: a comparative analysis
C. Argüelles (2000)
Archaebacterial bipolar tetraether lipids: Physico-chemical and membrane properties.
P. Chong (2010)
Short-Term Repeated-Dose Toxicity Profile of Archaeosomes Administered to Mice via Intravenous and Oral Routes
Abdelwahab Omri (2003)
Archaeabacteria bipolar lipid analogues: structure, synthesis and lyotropic properties
T. Benvegnu (2004)
Physiological roles of trehalose in bacteria and yeasts: a comparative analysis
J. C. Argüelles (2000)
Liposome membrane can act like molecular and metal chaperones for oxidized and fragmented superoxide dismutase
L. Q. Tuan (2009)
Preparation and Characterization of Stealth Archaeosomes Based on a Synthetic PEGylated Archaeal Tetraether Lipid
Julie Barbeau (2011)
Liposomes as Drug Delivery Systems: Properties and Applications
E. Moghimipour (2013)
The Potent Adjuvant Activity of Archaeosomes Correlates to the Recruitment and Activation of Macrophages and Dendritic Cells In Vivo1
L. Krishnan (2001)
Utilization of thin film method for preparation of celecoxib loaded liposomes.
E. Moghimipour (2012)
Functional reconstitution of membrane proteins in monolayer liposomes from bipolar lipids of Sulfolobus acidocaldarius.
M. Elferink (1992)
Review of health safety aspects of nanotechnologies in food production.
H. Bouwmeester (2009)
Immunization of mice with lipopeptide antigens encapsulated in novel liposomes prepared from the polar lipids of various Archaeobacteria elicits rapid and prolonged specific protective immunity against infection with the facultative intracellular pathogen, Listeria monocytogenes.
J. Conlan (2001)
Archaeosomes adjuvant overcome tolerance to tumour associated melanoma antigens inducing protective CD8 R T-cell responses
L Krishnan (2010)
Effect of Growth Medium pH of Aeropyrum pernix on Structural Properties and Fluidity of Archaeosomes
Ajda Ota (2012)
Archaeal tetraether bipolar lipids: Structures, functions and applications.
A. Jacquemet (2009)
Perspective on biotechnology application of archaea
C Schiraldi (2002)
Archaeosomes made of Halorubrum tebenquichense total polar lipids: a new source of adjuvancy
Raul O Gonzalez (2009)
Liposome adjuvants prepared from the total polar lipids of Haloferax volcanii, Planococcus spp. and Bacillus firmus differ in ability to elicit and sustain immune responses.
G. Sprott (2004)
Biotechnological uses of archaeal extremozymes.
J. Eichler (2001)
Archaeosomes based on synthetic tetraether-like lipids as novel versatile gene delivery systems.
G. Réthoré (2007)
Preparation and Characterization of Liposomes Containing Essential Oil of Eucalyptus camaldulensis Leaf
E. Moghimipour (2012)
Ultradeformable archaeosomes as new topical adjuvants.
L. Higa (2012)
Formulation and in vitro Evaluation of Topical Liposomal Gel of Triamcinolone Acetonide
E. Moghimipour (2013)
Liposomes properties and pharmaceutical applications. Lambert Academic Publishing
E Moghimipour (2013)
Archaea : evolution, physiology, and molecular biology
R. Garrett (2007)
Nanocarriers for Transmucosal Vaccine Delivery
S. Jain (2011)
New generation of liposomes called archaeosomes based on natural or synthetic archaeal lipids as innovative formulations for drug delivery.
T. Benvegnu (2009)
Archaeal lipids: innovative material foe biotechnology applications
T Benvegnu (2008)
Archaeosomes adjuvant overcome tolerance to tumour associated melanoma antigens inducing protective CD8 T-cell responses
L Krishnan (2010)
Perspectives on biotechnological applications of archaea.
C. Schiraldi (2002)
Archaeal Lipids: Innovative Materials for Biotechnological Applications
T. Benvegnu (2008)
Calcium-induced aggregation of archaeal bipolar tetraether liposomes derived from the thermoacidophilic archaeon Sulfolobus acidocaldarius.
Roby Kanichay (2003)
The role of high-resolution imaging in the evaluation of nanosystems for bioactive encapsulation and targeted nanoparticle
K Khosravani- Darani (2007)
Studies of archaebacterial bipolar tetraether liposomes by perylene fluorescence.
T. K. Khan (2000)
Two-photon fluorescence microscopy studies of bipolar tetraether giant liposomes from thermoacidophilic archaebacteria Sulfolobus acidocaldarius.
L. Bagatolli (2000)
Preparation of Curcumin-Loaded Liposomes and Evaluation of Their Skin Permeation and Pharmacodynamics
Y. Chen (2012)
Formation of unilamellar liposomes from total polar lipid extracts of methanogens.
C. Choquet (1992)
Liposomes properties and pharmaceutical applications
E Moghimipour (2013)
Preparation and characterization of stealth archaeosomes based on synthetic PEGylated archael tetraether lipid
J Barbeau (2011)
Investigation of archaeosomes as carriers for oral delivery of peptides.
Z. Li (2010)
The essence of being extremophilic: the role of the unique archaeal membrane lipids
J. L. V. D. van de Vossenberg (1998)
Microbiology online
Osmometric and microscopic studies on bilayers of polar lipids from the extreme halophile, Halobacterium cutirubrum.
J. S. Chen (1974)
Archaeosome Adjuvant Overcomes Tolerance to Tumor-Associated Melanoma Antigens Inducing Protective CD8+ T Cell Responses
L. Krishnan (2010)
Exploring the biotechnologial applications in the archaeal domain
S. Alquéres (2007)
The role of high-resolution imaging in the evaluation of nanosystems for bioactive encapsulation and targeted nanotherapy
K. Khosravi-Darani (2007)
Approaches for enhancing oral bioavailability of peptides and proteins.
J. Renukuntla (2013)
Liposomal drug delivery systems: an update review.
A. Samad (2007)
In vitro assessment of archaeosome stability for developing oral delivery systems.
G. B. Patel (2000)
Two photon fluorescence microscopy studies of bipolar tetraether giant liposomes from thermoacidophilic arechaebacteria Sulfolobus acidocaldarius
L Begatolli (2000)
Archaeosomes based on novel synthetic tetraether type lipids for the development of oral systems
T Benvegnu (2005)
Exploring the biotechnological application in the archaeal domain
SMC Alqueres (2007)

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