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Reduced Levels Of Chloroplast FtsH Protein In Tobacco Mosaic Virus–Infected Tobacco Leaves Accelerate The Hypersensitive Reaction

S. Seo, M. Okamoto, T. Iwai, Masataka Iwano, K. Fukui, A. Isogai, N. Nakajima, Y. Ohashi
Published 2000 · Medicine, Biology

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In tobacco cultivars resistant to tobacco mosaic virus (TMV), infection results in the death of the infected cells accompanying the formation of necrotic lesions. To identify the genes involved in this hypersensitive reaction, we isolated the cDNA of tobacco DS9, the transcript of which decreases before the appearance of necrotic lesions. The DS9 gene encodes a chloroplastic homolog of bacterial FtsH protein, which serves to maintain quality control of some cytoplasmic and membrane proteins. A large quantity of DS9 protein was found in healthy leaves, whereas the quantity of DS9 protein in infected leaves decreased before the lesions appeared. In transgenic tobacco plants containing less and more DS9 protein than wild-type plants, the necrotic lesions induced by TMV were smaller and larger, respectively, than those on wild-type plants. These results suggest that a decrease in the level of DS9 protein in TMV-infected cells, resulting in a subsequent loss of function of the chloroplasts, accelerates the hypersensitive reaction.
This paper references
A direct colorimeric assay
Chan (1986)
10.1111/J.1365-313X.1993.00875.X
Altered response to viral infection by tobacco plants perturbed in ubiquitin system.
F. Becker (1993)
10.1007/springerreference_35408
The heat shock response.
E. Craig (1985)
10.1006/BBRC.1999.1576
The antioxidant 4b,5,9b,10-Tetrahydroindeno[1,2-b]indole inhibits apoptosis by preventing caspase activation following mitochondrial depolarization.
G. P. Devitt (1999)
The nucleotide sequence of a tobacco homolog of Pftf . Evidence for two plastid - localized AAA - family proteins in higher plants ( accession no . AF 117339 ) ( PGR 99 – 029 )
E. J. Summer (1999)
10.1073/PNAS.87.22.8756
Analysis of gene families encoding acidic and basic beta-1,3-glucanases of tobacco.
H. Linthorst (1990)
10.1177/40.3.1552177
Lectin cytochemistry in the gastrointestinal tract with special reference to glycosylation in the Golgi apparatus of Brunner's gland cells.
E. Suzaki (1992)
10.1105/tpc.7.1.29
Coordinated Activation of Programmed Cell Death and Defense Mechanisms in Transgenic Tobacco Plants Expressing a Bacterial Proton Pump.
R. Mittler (1995)
Current Protocols in Molecular Biology. (New York: Wiley Interscience)
F. M. Ausubel (1987)
Heat shock and other stress response systems of plants.
D. Neumann (1989)
10.1002/j.1460-2075.1995.tb07253.x
Escherichia coli FtsH is a membrane‐bound, ATP‐dependent protease which degrades the heat‐shock transcription factor sigma 32.
T. Tomoyasu (1995)
10.1105/tpc.10.3.435
Activation of the Tobacco SIP Kinase by Both a Cell Wall–Derived Carbohydrate Elicitor and Purified Proteinaceous Elicitins from Phytophthora spp
S. Zhang (1998)
10.1016/0968-0004(92)90503-2
Too much of a good thing: light can be bad for photosynthesis.
J. Barber (1992)
10.1006/EXCR.1997.3832
Contribution of gene-specific lesions, DNA-replication-associated damage, and subsequent transcriptional inhibition in topoisomerase inhibitor-mediated apoptosis in lymphoma cells.
D. E. Muscarella (1998)
The nucleotide sequence of a tobacco homolog of Pftf. Evidence for two plastid-localized AAAfamily proteins in higher plants (accession no. AF117339) (PGR 99–029)
E. J. Summer (1999)
10.1016/0966-842X(96)81499-5
Sacrifice in the face of foes: pathogen-induced programmed cell death in plants.
R. Mittler (1996)
10.1073/PNAS.93.10.5116
Oxidative stress is involved in heat-induced cell death in Saccharomyces cerevisiae.
J. F. Davidson (1996)
10.1128/JB.178.21.6151-6157.1996
Sequencing, expression, and genetic characterization of the Helicobacter pylori ftsH gene encoding a protein homologous to members of a novel putative ATPase family.
Z. Ge (1996)
10.1016/0092-8674(94)90283-6
The product of the tobacco mosaic virus resistance gene N: Similarity to toll and the interleukin-1 receptor
S. Whitham (1994)
The nucleotide sequence of a tobacco homolog of Pftf . Evidence for two plastid - localized AAA - family proteins in higher plants ( accession no . AF 117339 ) ( PGR 99 – 029 )
E. J. Summer (1999)
10.1111/J.1399-3054.1996.TB00523.X
The ubiquitin system in plants
Jan von Kampen (1996)
10.1128/MCB.15.8.4441
Multiple genes, including a member of the AAA family, are essential for degradation of unassembled subunit 2 of cytochrome c oxidase in yeast mitochondria.
T. Nakai (1995)
10.1104/PP.24.1.1
COPPER ENZYMES IN ISOLATED CHLOROPLASTS. POLYPHENOLOXIDASE IN BETA VULGARIS.
D. Arnon (1949)
The HflB protease of Escherichia coli degrades its inhibitor cIII
C Herman (1997)
10.1093/OXFORDJOURNALS.PCP.A029609
Ethylene Promotes the Necrotic Lesion Formation and Basic PR Gene Expression in TMV-Infected Tobacco
N. Ohtsubo (1999)
10.1111/J.1439-0434.1971.TB03477.X
Necrosis and Localization of Infection in Local Lesion Hosts
T. Shimomura (1971)
10.1016/0003-2697(84)90553-0
Fluorescein isothiocyanate-labeled casein assay for proteolytic enzymes.
S. Twining (1984)
10.1016/0042-6822(72)90072-4
Induction of localized necrotic lesions by actinomycin D on leaves systemically infected with tobacco mosaic virus.
Y. Oashi (1972)
Inheritance of resistance to tobaccomosaic disease in tobacco
F. O. Holmes (1938)
10.3186/JJPHYTOPATH.42.436
Leakage of Cell Constituents Associated with Local Lesion Formation on Nicotiana glutinosa Leaf Infected with Tobacco Mosaic virus
Y. Ohashi (1976)
Inheritance of resistance to Tobacco-mosaic disease in Tobacco.
F. O. Holmes (1938)
10.1146/ANNUREV.PY.28.090190.000553
Plant Pathogenesis-Related Proteins Induced by Virus Infection
J. Bol (1990)
10.1146/ANNUREV.BI.50.070181.001111
DNA modification and cancer.
M. Waring (1981)
10.1128/MCB.19.5.3704
Transcription Factor E2F-1 Is Upregulated in Response to DNA Damage in a Manner Analogous to That of p53
C. Blattner (1999)
10.1105/tpc.11.2.289
Jasmonate-Based Wound Signal Transduction Requires Activation of WIPK, a Tobacco Mitogen-Activated Protein Kinase
S. Seo (1999)
Photoinhibition of photosynthesis induced by visible light
Sb Powels (1984)
10.1128/JB.179.2.358-363.1997
The HflB protease of Escherichia coli degrades its inhibitor lambda cIII.
C. Herman (1997)
10.1002/j.1460-2075.1996.tb01000.x
A protease complex in the Escherichia coli plasma membrane: HflKC (HflA) forms a complex with FtsH (HflB), regulating its proteolytic activity against SecY.
A. Kihara (1996)
Copper enzymes in isolated chloroplasts
D. I. Arnon (1949)
10.1073/PNAS.95.13.7433
Resistance gene N-mediated de novo synthesis and activation of a tobacco mitogen-activated protein kinase by tobacco mosaic virus infection.
S. Zhang (1998)
10.1111/J.1399-3054.1997.TB00005.X
Proteolytic activities and proteases of plant chloroplasts
B. Andersson (1997)
10.1016/0042-6822(71)90331-X
Conditioning of local lesion formation by a brief heat or cold treatment of leaves systemically infected with TMV.
T. Shimomura (1971)
10.1105/tpc.8.10.1793
Death Don't Have No Mercy: Cell Death Programs in Plant-Microbe Interactions.
J. Dangl (1996)
The hypersensitive reaction in plants to pathogens: a resistance phenomenon.
R. Goodman (1994)
10.1073/PNAS.96.11.6547
GTP bound to chloroplast thylakoid membranes is required for light-induced, multienzyme degradation of the photosystem II D1 protein.
C. Spetea (1999)
10.1104/PP.85.4.942
Classification and Structural Comparison of Full-Length cDNAs for Pathogenesis-Related Proteins.
M. Matsuoka (1987)
Necrotic lesion formation and localization of infection in virus-infected plants.
T. Shimomura (1980)
10.1128/MCB.13.9.5418
Inactivation of YME1, a member of the ftsH-SEC18-PAS1-CDC48 family of putative ATPase-encoding genes, causes increased escape of DNA from mitochondria in Saccharomyces cerevisiae.
P. Thorsness (1993)
10.1007/BF00020476
Protein stability and degradation in chloroplasts
Z. Adam (2004)
10.1104/PP.90.3.867
Electrolyte Leakage, Lipoxygenase, and Lipid Peroxidation Induced in Tomato Leaf Tissue by Specific and Nonspecific Elicitors from Cladosporium fulvum.
T. L. Peever (1989)
10.1074/jbc.274.24.17325
Nitric Oxide Suppresses Apoptosis via Interrupting Caspase Activation and Mitochondrial Dysfunction in Cultured Hepatocytes*
J. Li (1999)
10.1105/tpc.10.6.889
An Arabidopsis Mutant Hypersensitive to Red and Far-Red Light Signals
T. Genoud (1998)
Resistance gene Nmediated de novo synthesis and activation of a tobacco mitogen - activated protein kinase by tobacco mosaic virus infection
S. Zhang (1998)
10.1016/0076-6879(87)48018-X
[16] Isolation of plastids in density gradients of percoll and other silica sols
C. Price (1987)
10.1074/jbc.271.49.31196
FtsH (HflB) Is an ATP-dependent Protease Selectively Acting on SecY and Some Other Membrane Proteins*
Y. Akiyama (1996)
10.1104/PP.119.4.1233
The relationship between photosynthesis and a mastoparan-induced hypersensitive response in isolated mesophyll cells
Allen (1999)
10.1002/BIES.950170710
A 200‐amino acid ATPase module in search of a basic function
F. Confalonieri (1995)
10.1016/0005-2728(93)90134-2
Photoinhibition of Photosystem II. Inactivation, protein damage and turnover.
E. Aro (1993)
10.1104/PP.96.4.1048
Heat Shock Causes Selective Destabilization of Secretory Protein mRNAs in Barley Aleurone Cells.
M. Brodl (1991)
10.1126/science.274.5284.103
Promotion of Mitochondrial Membrane Complex Assembly by a Proteolytically Inactive Yeast Lon
M. Rep (1996)
The nucleotide sequence of a tobacco homolog of Pftf . Evidence for two plastidlocalized AAAfamily proteins in higher plants ( accession no . AF 117339 ) ( PGR 99 – 029 )
E. J. Summer (1999)
10.1105/tpc.9.6.957
Light-stimulated degradation of an unassembled Rieske FeS protein by a thylakoid-bound protease: the possible role of the FtsH protease.
O. Ostersetzer (1997)
10.1016/S0048-4059(81)80086-0
Lesion growth and virus localization in leaves of Nicotiana tabacum cv. Xanthi nc. after inoculation with tobacco mosaic virus and incubation alternately at 22°C and 32°C
E. A. Weststeijn (1981)
The relationship between photosynthesis
L. J. Allen (1999)
10.1074/jbc.271.46.29329
Identification, Characterization, and Molecular Cloning of a Homologue of the Bacterial FtsH Protease in Chloroplasts of Higher Plants*
M. Lindahl (1996)
10.1126/science.270.5244.1988
Tobacco MAP Kinase: A Possible Mediator in Wound Signal Transduction Pathways
S. Seo (1995)
Involvement of FtsH in protein assembly into and through the membrane. II. Dominant mutations affecting FtsH functions.
Y. Akiyama (1994)
The heatshock response
S. Lindquist (1986)
10.1101/GAD.11.7.815
Protein quality control: triage by chaperones and proteases.
S. Gottesman (1997)
10.1126/SCIENCE.227.4691.1229
A simple and general method for transferring genes into plants.
R. Horsch (1985)
10.1128/JB.175.5.1344-1351.1993
The Escherichia coli FtsH protein is a prokaryotic member of a protein family of putative ATPases involved in membrane functions, cell cycle control, and gene expression.
T. Tomoyasu (1993)
10.1128/JB.175.5.1352-1357.1993
Topology and subcellular localization of FtsH protein in Escherichia coli.
T. Tomoyasu (1993)
10.1111/J.1432-1033.1989.TB14679.X
Domain structure of mitochondrial and chloroplast targeting peptides.
G. von Heijne (1989)
10.1016/0003-2697(86)90640-8
A direct colorimetric assay for Ca2+ -stimulated ATPase activity.
K. Chan (1986)
10.1016/S0014-5793(96)01283-5
Subunit a of proton ATPase F0 sector is a substrate of the FtsH protease in Escherichia coli
Y. Akiyama (1996)
10.1073/PNAS.92.8.3516
Degradation of sigma 32, the heat shock regulator in Escherichia coli, is governed by HflB.
C. Herman (1995)
10.1104/PP.119.3.1147
The electronic plant gene register.
M. Schmidt (1999)
10.1111/J.1744-7348.1952.TB01018.X
SOME EFFECTS OF HIGH TEMPERATURE ON THE SUSCEPTIBILITY OF PLANTS TO INFECTION WITH VIRUSES
B. Kassanis (1952)



This paper is referenced by
10.1111/J.1469-8137.2006.01707.X
Seduced by the dark side: integrating molecular and ecological perspectives on the influence of light on plant defence against pests and pathogens.
M. Roberts (2006)
10.2174/2212796810802010011
Towards Understanding the Roles of Prohibitins, Multi-Functional Regulator Proteins
A. Hofmann (2008)
10.1073/PNAS.98.2.771
The Arabidopsis-accelerated cell death gene ACD2 encodes red chlorophyll catabolite reductase and suppresses the spread of disease symptoms.
J. M. Mach (2001)
10.1093/PCP/PCH057
Comparative analysis of expressed sequence tags in resistant and susceptible ecotypes of Arabidopsis thaliana infected with cucumber mosaic virus.
T. Ishihara (2004)
The Chloroplastic Protein THF 1 Interacts with the Coiled-Coil Domain of the Disease Resistance Protein N 9 and Regulates Light-Dependent Cell Death 1 [ OPEN ]
Louis-Philippe Hamel (2016)
10.1104/PP.126.4.1637
Expression of 35S::Pto globally activates defense-related genes in tomato plants.
F. Xiao (2001)
10.1093/PCP/PCE096
In vivo detection of tobacco mosaic virus-induced local and systemic oxidative burst by electron paramagnetic resonance spectroscopy.
J. Fodor (2001)
10.1093/PCP/PCF122
Enhanced resistance to salt, cold and wound stresses by overproduction of animal cell death suppressors Bcl-xL and Ced-9 in tobacco cells - their possible contribution through improved function of organella.
Jingbo Qiao (2002)
10.5772/53127
Programmed Cell Death as a Response to High Light, UV and Drought Stress in Plants
Weronika Wituszyńska (2013)
10.1038/nrm1358
Controlled cell death, plant survival and development
Eric Lam (2004)
10.1094/MPMI-05-10-0113
All hands on deck—the role of chloroplasts, endoplasmic reticulum, and the nucleus in driving plant innate immunity.
M. Padmanabhan (2010)
10.1590/S1415-47572001000100025
Mitochondrial and chloroplast localization of FtsH-like proteins in sugarcane based on their phylogenetic profile
P. A. S. Marbach (2001)
10.1093/PCP/PCI243
Accumulation of the two transcripts of the N gene, conferring resistance to tobacco mosaic virus, is probably important for N gene-dependent hypersensitive cell death.
Reona Takabatake (2006)
10.1155/2007/17542
Temporal Gene Expression Profiling of the Wheat Leaf Rust Pathosystem Using cDNA Microarray Reveals Differences in Compatible and Incompatible Defence Pathways
B. Fofana (2007)
10.1105/tpc.108.059618
Chloroplast Signaling and LESION SIMULATING DISEASE1 Regulate Crosstalk between Light Acclimation and Immunity in Arabidopsis[W]
Per Mühlenbock (2008)
10.1007/s10930-018-9775-9
Chloroplast Proteome of Nicotiana benthamiana Infected by Tomato Blistering Mosaic Virus
Esaú Megías (2018)
10.1023/A:1021577521522
Chlorophyll-Deficient Mutant in Oak (Quercus petraea L.) Displays an Accelerated Hypersensitive-Like Cell Death and an Enhanced Resistance to Powdery Mildew Disease
V. Řepka (2004)
10.1023/A:1025576307912
Participation of Chloroplasts in Plant Apoptosis
V. Samuilov (2003)
10.1007/s10495-009-0447-2
Apoptotic-like regulation of programmed cell death in plants
Theresa J. Reape (2009)
10.1046/j.1365-2443.2002.00558.x
The VAR1 locus of Arabidopsis encodes a chloroplastic FtsH and is responsible for leaf variegation in the mutant alleles
W. Sakamoto (2002)
10.1111/J.1365-313X.2003.02014.X
The Arabidopsis FtsH metalloprotease gene family: interchangeability of subunits in chloroplast oligomeric complexes.
F. Yu (2004)
10.1093/JB/MVJ014
A higher plant has three different types of RPA heterotrimeric complex.
T. Ishibashi (2006)
10.1093/PCP/PCJ074
Regulatory mechanisms of ROI generation are affected by rice spl mutations.
K. Kojo (2006)
10.1016/S1937-6448(08)01403-2
Programmed cell death in plants: new insights into redox regulation and the role of hydrogen peroxide.
Ilya Gadjev (2008)
10.1111/j.1469-8137.2010.03377.x
Accumulation of chlorophyll catabolites photosensitizes the hypersensitive response elicited by Pseudomonas syringae in Arabidopsis.
L. Mur (2010)
10.1007/s00299-012-1243-y
Exogenous thermospermine has an activity to induce a subset of the defense genes and restrict cucumber mosaic virus multiplication in Arabidopsis thaliana
G H M Sagor (2012)
10.1093/pcp/pcr189
Variegated tobacco leaves generated by chloroplast FtsH suppression: implication of FtsH function in the maintenance of thylakoid membranes.
Y. Kato (2012)
10.1111/mpp.12533
Chloroplast: the Trojan horse in plant-virus interaction.
Dhriti Bhattacharyya (2018)
10.1016/j.plaphy.2017.12.012
Osmotin: A plant defense tool against biotic and abiotic stresses.
Hakim (2018)
CELL SUICIDE OR PROGRAMMED CELL DEATH
M. M. E. م. م. الساهوكي (2009)
10.11606/T.11.2003.TDE-20102003-161703
CLONAGEM, CARACTERIZAÇÃO DA EXPRESSÃO GÊNICA E DO TRANSPORTE INTRA-ORGANELAR DA PROTEASE FtsH-p1 DE TOMATE (Lycopersicon esculentum Mill. cv. MicroTom)
R. M. Barata (2003)
10.1590/S0100-41582005000100002
Sugarcane yellow leaf virus infection leads to alterations in photosynthetic efficiency and carbohydrate accumulation in sugarcane leaves
M. C. Gonçalves (2005)
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