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The RLA1/SMOS1 Transcription Factor Functions With OsBZR1 To Regulate Brassinosteroid Signaling And Rice Architecture
Shenglong Qiao, Shiyong Sun, Linlin Wang, Z. Wu, Chengxiang Li, Xiaoming Li, T. Wang, L. Leng, W. Tian, Tiegang Lu, Xuelu Wang
Published 2017 · Medicine, Biology
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The RLA1/SMOS1 transcription factor acts as an integrator of the transcriptional complex directly downstream of the kinase GSK2 and plays an essential role in BR signaling and development in rice. Brassinosteroids (BRs) are plant-specific steroid hormones that control plant growth and development. Recent studies have identified key components of the BR signaling pathway in Arabidopsis thaliana and in rice (Oryza sativa); however, the mechanism of BR signaling in rice, especially downstream of GSK3/SHAGGY-like kinase (GSK2), remains unclear. Here, we identified a BR-insensitive rice mutant, reduced leaf angle1 (rla1), and cloned the corresponding gene. RLA1 was identical to the previously reported SMALL ORGAN SIZE1 (SMOS1), which was cloned from another allele. RLA1/SMOS1 encodes a transcription factor with an APETALA2 DNA binding domain. Genetic analysis indicated that RLA1/SMOS1 functions as a positive regulator in the BR signaling pathway and is required for the function of BRASSINAZOLE-RESISTANT1 (OsBZR1). In addition, RLA1/SMOS1 can interact with OsBZR1 to enhance its transcriptional activity. GSK2 can interact with and phosphorylate RLA1/SMOS1 to reduce its stability. These results demonstrate that RLA1/SMOS1 acts as an integrator of the transcriptional complex directly downstream of GSK2 and plays an essential role in BR signaling and plant development in rice.
This paper references
Biosynthesis of Brassinosteroids in Seedlings of Catharanthus roseus, Nicotiana tabacum, and Oryza sativa
H. Suzuki (1995)
Biosynthesis of Brassinosteroids
H. Suzuki (1995)
A Putative Leucine-Rich Repeat Receptor Kinase Involved in Brassinosteroid Signal Transduction
J. Li (1997)
BRASSINOSTEROIDS: Essential Regulators of Plant Growth and Development.
S. Clouse (1998)
Loss of Function of a Rice brassinosteroid insensitive1 Homolog Prevents Internode Elongation and Bending of the Lamina Joint
C. Yamamuro (2000)
BIN2, a new brassinosteroid-insensitive locus in Arabidopsis.
J. Li (2001)
Nuclear-localized BZR1 mediates brassinosteroid-induced growth and feedback suppression of brassinosteroid biosynthesis.
Z. Y. Wang (2002)
BES1 Accumulates in the Nucleus in Response to Brassinosteroids to Regulate Gene Expression and Promote Stem Elongation
Y. Yin (2002)
BAK1, an Arabidopsis LRR Receptor-like Protein Kinase, Interacts with BRI1 and Modulates Brassinosteroid Signaling
J. Li (2002)
Regulation of Brassinosteroid Signaling by a GSK3/SHAGGY-Like Kinase
J. Li (2002)
The Plant Architecture of Rice (Oryza sativa)
Y. Wang (2005)
Nuclear protein phosphatases with Kelch-repeat domains modulate the response to brassinosteroids in Arabidopsis.
S. Mora-García (2004)
EXORDIUM regulates brassinosteroid‐responsive genes
D. Coll-García (2004)
Autoregulation and homodimerization are involved in the activation of the plant steroid receptor BRI1.
Xuelu Wang (2005)
A New Class of Transcription Factors Mediates Brassinosteroid-Regulated Gene Expression in Arabidopsis
Y. Yin (2005)
Transient expression vectors for functional genomics, quantification of promoter activity and RNA silencing in plants
R. Hellens (2005)
Brassinosteroids Regulate Dissociation of BKI1, a Negative Regulator of BRI1 Signaling, from the Plasma Membrane
Xuelu Wang (2006)
Downstream nuclear events in brassinosteroid signalling
G. Vert (2006)
Morphological Alteration Caused by Brassinosteroid Insensitivity Increases the Biomass and Grain Production of Rice1
Yoichi Morinaka (2006)
Phosphate-binding Tag, a New Tool to Visualize Phosphorylated Proteins*S
Erect leaves caused by brassinosteroid deficiency increase biomass production and grain yield in rice
T. Sakamoto (2006)
A practical vector for efficient knockdown of gene expression in rice (Oryza sativa L.)
Zhen Wang (2004)
T-DNA tagged knockout mutation of rice OsGSK1, an orthologue of Arabidopsis BIN2, with enhanced tolerance to various abiotic stresses
S. Koh (2007)
Arabidopsis mesophyll protoplasts: a versatile cell system for transient gene expression analysis
Sang-Dong Yoo (2007)
Functions of OsBZR1 and 14-3-3 proteins in brassinosteroid signaling in rice
M. Bai (2007)
TEAD mediates YAP-dependent gene induction and growth control.
Bin Zhao (2008)
BSKs Mediate Signal Transduction from the Receptor Kinase BRI1 in Arabidopsis
W. Tang (2008)
OsLIC, a Novel CCCH-Type Zinc Finger Protein with Transcription Activation, Mediates Rice Architecture via Brassinosteroids Signaling
L. Wang (2008)
Structural insights into the negative regulation of BRI 1 signaling by BRI 1 - interacting protein BKI 1
L. Wang (2008)
Arabidopsis MYB30 is a direct target of BES1 and cooperates with BES1 to regulate brassinosteroid-induced gene expression.
Lei Li (2009)
Brassinosteroid signal transduction from cell-surface receptor kinases to nuclear transcription factors
Tae-Wuk Kim (2009)
BRASSINOSTEROID UPREGULATED 1 , Encoding a Helix-Loop-Helix Protein , Is a Novel Gene Involved in Brassinosteroid Signaling and Controls Bending of the Lamina Joint in Rice 1 [ W ] [ OA ]
A. Tanaka (2009)
Antagonistic HLH/bHLH Transcription Factors Mediate Brassinosteroid Regulation of Cell Elongation and Plant Development in Rice and Arabidopsis[C][W][OA]
L. Zhang (2009)
Engineering OsBAK1 gene as a molecular tool to improve rice architecture for high yield.
D. Li (2009)
BRASSINOSTEROID UPREGULATED1, Encoding a Helix-Loop-Helix Protein, Is a Novel Gene Involved in Brassinosteroid Signaling and Controls Bending of the Lamina Joint in Rice1[W][OA]
A. Tanaka (2009)
DWARF AND LOW-TILLERING, a new member of the GRAS family, plays positive roles in brassinosteroid signaling in rice.
Hongning Tong (2009)
Arabidopsis MYB 30 is a direct target of BES 1 and cooperates with BES 1 to regulate brassinosteroid - induced gene expression
L. Li (2009)
Dual role of BKI1 and 14-3-3 s in brassinosteroid signaling to link receptor with transcription factors.
Haijiao Wang (2011)
Gene structures, classification and expression models of the AP2/EREBP transcription factor family in rice.
A. M. Sharoni (2011)
The mechanisms of brassinosteroids' action: from signal transduction to plant development.
Cangjing Yang (2011)
Dual role of BKI1
H. Wang (2011)
DWARF AND LOW-TILLERING Acts as a Direct Downstream Target of a GSK3/SHAGGY-Like Kinase to Mediate Brassinosteroid Responses in Rice[W][OA]
Hongning Tong (2012)
Wnt/β-Catenin Signaling and Disease
H. Clevers (2012)
Dynamics of Brassinosteroid Response Modulated by Negative Regulator LIC in Rice
C. Zhang (2012)
MYBL2 is a substrate of GSK3-like kinase BIN2 and acts as a corepressor of BES1 in brassinosteroid signaling pathway in Arabidopsis
H. Ye (2012)
Genome-wide identification of transcription factor-binding sites in plants using chromatin immunoprecipitation followed by microarray (ChIP-chip) or sequencing (ChIP-seq).
Jiaying Zhu (2012)
H. 7554eLife.02525. Clevers (2012)
Strigolactone/MAX2-induced degradation of brassinosteroid transcriptional effector BES1 regulates shoot branching.
Y. Wang (2013)
OsGRAS19 may be a novel component involved in the brassinosteroid signaling pathway in rice.
Li-sheng Chen (2013)
Auxin signal transcription factor regulates expression of the brassinosteroid receptor gene in rice.
T. Sakamoto (2013)
The Hippo signaling pathway in stem cell biology and cancer
J. Mo (2014)
A novel AP2-type transcription factor, SMALL ORGAN SIZE1, controls organ size downstream of an auxin signaling pathway.
K. Aya (2014)
Brassinosteroid-mediated regulation of agronomic traits in rice
Cui Zhang (2014)
Structural insights into the negative regulation of BRI1 signaling by BRI1-interacting protein BKI1
Jie Wang (2014)
GSK3-like kinases positively modulate abscisic acid signaling through phosphorylating subgroup III SnRK2s in Arabidopsis
Zhenying Cai (2014)
Brassinosteroids control root epidermal cell fate via direct regulation of a MYB-bHLH-WD40 complex by GSK3-like kinases
Yinwei Cheng (2014)
Transcription factor HAT1 is phosphorylated by BIN2 kinase and mediates brassinosteroid repressed gene expression in Arabidopsis.
Dawei Zhang (2014)
Transcription factor HAT 1 is phosphorylated by BIN 2 kinase and mediates brassinosteroid repressed gene expression in Arabidopsis
D. Zhang (2014)
GSK 3 - like kinases positively modulate abscisic acid signaling through phosphorylating subgroup III SnRK 2 s in Arabidopsis
Z. Cai (2014)
Brassinosteroid signaling regulates leaf erectness in Oryza sativa via the control of a specific U-type cyclin and cell proliferation.
S. Sun (2015)
A Recently Evolved Isoform of the Transcription Factor BES1 Promotes Brassinosteroid Signaling and Development in Arabidopsis thaliana
J. Jiang (2015)
Functional insights of plant GSK3-like kinases: multi-taskers in diverse cellular signal transduction pathways.
Ji-Hyun Youn (2015)
The auxin response factor, OsARF19, controls rice leaf angles through positively regulating OsGH3-5 and OsBRI1.
Saina Zhang (2015)
The auxin response factor, OsARF19
S. Zhang (2015)
A recently evolved isoform
J. Jiang (2015)
A practical vector for ef fi cient knockdown of gene expression in rice ( Oryza sativa L . )
Z. Y. Wang
This paper is referenced by
Transcription factor BZR2 activates chitinase Cht20.2 transcription to confer resistance to wheat stripe rust.
Xingxuan Bai (2021)
Leaf direction: lamina joint development and environmental responses.
Jing Xu (2021)
Genome-Wide Identification of Brassinosteroid Signaling Downstream Genes in Nine Rosaceae Species and Analyses of Their Roles in Stem Growth and Stress Response in Apple
Liwei Zheng (2021)
Characterization of novel regulatory modules controlling leaf angle in maize
Xianglan Wang (2021)
A multifaceted module of BRI1 ETHYLMETHANE SULFONATE SUPRESSOR1 (BES1)-MYB88 in growth and stress tolerance of apple.
Xiaofang Liu (2021)
Epigenetic regulation of nitrogen and phosphorus responses in plants.
A. Li (2021)
BZR1 Regulates Brassinosteroid-Mediated Activation of AMT1;2 in Rice
Shuo Yang (2021)
Versatile Physiological Functions of Plant GSK3-Like Kinases
Juan Mao (2021)
Separable regulation of POW1 in grain size and leaf angle development in rice.
Li Zhang (2021)
WRKY53 Integrates Classic Brassinosteroid Signaling and the Mitogen-Activated Protein Kinase Pathway to Regulate Rice Architecture and Seed Size.
Xiaojie Tian (2021)
GSK3s: nodes of multilayer regulation of plant development and stress responses.
Chengxiang Li (2021)
OsGRAS19 and OsGRAS32 Control Tiller Development in Rice
Jinwon Lee (2021)
A bHLH protein, OsBIM1, positively regulates rice leaf angle by promoting brassinosteroid signaling.
Quanxiang Tian (2021)
Genome-Wide Identification and Characterization of the Brassinazole-resistant (BZR) Gene Family and Its Expression in the Various Developmental Stage and Stress Conditions in Wheat (Triticum aestivum L.)
Mahipal Singh Kesawat (2021)
Origin, evolution, and molecular function of DELLA proteins in plants
Huidan Xue (2021)
OsRELA Regulates Leaf Inclination by Repressing the Transcriptional Activity of OsLIC in Rice
Chen-li Zhu (2021)
14-3-3 Proteins Are Involved in BR-Induced Ray Petal Elongation in Gerbera hybrida
Xiaohui Lin (2021)
GSK3-Mediated Stress Signaling Inhibits Legume-Rhizobium Symbiosis by Phosphorylating GmNSP1 in Soybean.
Chunmei He (2020)
Molecular Characterization and Expression Patterns of Shabby-Related Kinase (MmSK) Gene of Mulberry (Morus multicaulis)
Fei Hu (2020)
Oryza sativa LIGULELESS 2s determine lamina joint positioning and differentiation by inhibiting auxin signaling.
Rongna Wang (2020)
Synergistic Interaction of Phytohormones in Determining Leaf Angle in Crops
Xi Li (2020)
Transcriptomic and physiological analyses of rice seedlings under different nitrogen supplies provide insight into the regulation involved in axillary bud outgrowth
Rongna Wang (2020)
Genome-wide identification and characterization of the BES1 gene family in apple (Malus domestica).
Xuejing Cao (2020)
The Role of Brassinosteroids in Controlling Plant Height in Poaceae: A Genetic Perspective
G. Castorina (2020)
Transcription factors-DNA interactions in rice: identification and verification
Zijie Shen (2020)
Effect of exogenous plant hormones on agronomic and physiological performance of a leaf early-senescent rice mutant osled
Yunji Xu (2020)
Rice stripe virus suppresses jasmonic acid-mediated resistance by hijacking brassinosteroid signaling pathway in rice
Jinlong Hu (2020)
The conserved brassinosteroid-related transcription factor BIM1a negatively regulates fruit growth in tomato.
K. Mori (2020)
Enhanced sustainable green revolution yield via nitrogen-responsive chromatin modulation in rice
Kun Wu (2020)
Rice dwarf and low tillering 10 (OsDLT10) regulates tiller number by monitoring auxin homeostasis.
Xiaoxia Wen (2020)
Silencing the SLB3 transcription factor gene decreases drought stress tolerance in tomato
Ziyu Wang (2020)
The histone deacetylase HDA703 interacts with OsBZR1 to regulate rice brassinosteroid signaling, growth and heading date through repression of Ghd7 expression.
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