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Enhanced Evanescent Confinement In Multiple-Slot Waveguides And Its Application In Biochemical Sensing

H. Sun, A. Chen, L. Dalton
Published 2009 · Materials Science

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The interaction of light propagating in the wave-guiding structures with the surrounding media through its evanescent field has been used to detect biochemical activities without labeling the target molecules. By introducing multiple slots in a dielectric waveguide, we found that a much stronger evanescent field could be achieved in the surrounding media while still maintaining good optical confinement. The experimental demonstration of microring resonator sensors using single-mode waveguides having three slots indicates a 5-fold increase in sensitivity for homogeneous sensing and more than 3-fold increase in sensitivity for surface sensing in comparison to those of a waveguide without slots. Numerical simulations suggest an even higher sensitivity enhancement (as high as 100 times) as more slots and larger waveguide widths are used.
This paper references
10.1021/la7005502
Direct immobilization of cholesteryl-TEG-modified oligonucleotides onto hydrophobic SU-8 surfaces.
Yavuz Erkan (2007)
Imbro, BTechnology challenges in responding to biological or chemical attacks in the civilian
J. P. Fitch (2003)
10.1109/JSTQE.2004.841716
Field modeling of circular microresonators by film mode matching
L. Prkna (2005)
10.3390/S7040508
Guided-Wave Optical Biosensors
V. Passaro (2007)
B Slot - waveguide biochemical sensor
F. Dell’Olio
10.1038/nature05741
Weighing of biomolecules, single cells and single nanoparticles in fluid
T. Burg (2007)
B Integrated - optical directional coupler biosensor
S. Balslev
10.1126/SCIENCE.1145002
Label-Free, Single-Molecule Detection with Optical Microcavities
A. M. Armani (2007)
10.1364/OE.15.017967
Horizontal single and multiple slot waveguides: optical transmission at λ=1550 nm
R. Sun (2007)
10.1126/SCIENCE.1088755
Nanoparticle-Based Bio-Bar Codes for the Ultrasensitive Detection of Proteins
J. Nam (2003)
BLabel-free detection: New biosensors facilitate broader range of drug discovery applications,
J. Comley (2005)
10.1002/bit.10507
Composite surface for blocking bacterial adsorption on protein biochips.
Tom Huang (2003)
10.1126/SCIENCE.1062711
Nanowire Nanosensors for Highly Sensitive and Selective Detection of Biological and Chemical Species
Yunlong Cui (2001)
10.1364/OE.15.004977
Optical sensing by optimized silicon slot waveguides.
F. Dell'Olio (2007)
10.1364/OL.21.000618
Integrated-optical directional coupler biosensor.
B. J. Luff (1996)
10.1529/BIOPHYSJ.103.030072
The density and refractive index of adsorbing protein layers.
J. Vörös (2004)
10.1364/OL.29.001209
Guiding and confining light in void nanostructure.
V. Almeida (2004)
10.1364/OL.29.001626
Experimental demonstration of guiding and confining light in nanometer-size low-refractive-index material.
Q. Xu (2004)
B Horizontal single and multiple slot waveguides : Optical transmission at  1⁄4 1550 nm
C. Hong
10.1364/AO.42.005649
Realization of a multichannel integrated Young interferometer chemical sensor.
A. Ymeti (2003)
10.1126/science.1088755
Nanoparticle-Based Bio-Bar Codes for the Ultrasensitive Detection of Proteins
Jwa-Min Nam (2003)
10.1364/OL.32.003080
Slot-waveguide biochemical sensor.
C. Barrios (2007)
10.1109/JSTQE.2005.862945
Polymer microring resonators for biochemical sensing applications
Chung-Yen Chao (2006)
10.1038/nrd838
Optical biosensors in drug discovery
M. Cooper (2002)
10.1126/SCIENCE.1085922
Technology Challenges in Responding to Biological or Chemical Attacks in the Civilian Sector
J. P. Fitch (2003)
10.1126/SCIENCE.1090899
Nanowire Crossbar Arrays as Address Decoders for Integrated Nanosystems
Zhaohui Zhong (2003)
10.1364/IQEC.2004.ITHI3
Ultra compact biochemical sensor built with two dimensional photonic crystal microcavity
E. Chow (2004)
10.1016/S0925-4005(98)00321-9
Surface plasmon resonance sensors: review
J. Homola (1999)
10.1109/JSTQE.2004.841693
Quasi-one-dimensional photonic crystal as a compact building-block for refractometric optical sensors
W.C.L. Hopman (2005)
BConcentrative properties of aqueous solutions,[ in CRC Handbook of Chemistry and Physics, 88th ed
D. R. Lide (2007)
10.1021/LA7005502
Direct immobilization of cholesteryl-TEG-modified oligonucleotides onto hydrophobic SU-8 surfaces.
Y. Erkan (2007)
10.1038/90216
Nanopores with a spark for single-molecule detection
H. Wang (2001)
BOptical biosensors in drug discovery,
M. A. Cooper (2002)
10.1039/B512546D
Lab-on-a-chip with integrated optical transducers.
S. Balslev (2006)
10.1002/BIT.10507
Composite surface for blocking bacterial adsorption on protein biochips.
T. Huang (2003)
10.1016/S0142-9612(02)00565-3
Biocompatibility and biofouling of MEMS drug delivery devices.
G. Voskerician (2003)
10.1007/S002160051553
Label-free detection of biomolecular interaction by optical sensors
H. Haake (2000)
10.1080/00032710500205659
Biosensors in Drug Discovery and Drug Analysis
Donghui Yu (2005)
10.1364/OL.29.001093
Ultra compact biochemical sensor built with two dimensional photonic crystal microcavity
E. Chow (2004)
10.1088/0957-4484/14/8/312
An integrated optical interferometric nanodevice based on silicon technology for biosensor applications
Francisco Prieto (2003)
10.1109/LPT.2006.887374
A Silicon-on-Insulator Photonic Wire Based Evanescent Field Sensor
A. Densmore (2006)
10.1109/JLT.2005.863333
Design and optimization of microring resonators in biochemical sensing applications
Chung-Yen Chao (2006)



This paper is referenced by
10.5277/OA180115
Optimization of a dual-slot waveguide for a refractive index biosensor
Sourabh Sahu (2018)
PHOTONIC STRUCTURES BASED ON SLOT WAVEGUIDES FOR NANOSENSORS: STATE OF THE ART AND FUTURE DEVELOPMENTS
V. Passaro (2012)
10.5772/30719
Chemical Sensors Based on Photonic Structures
V. Passaro (2012)
10.1364/OE.22.007229
Polymeric slot waveguide interferometer for sensor applications.
M. Hiltunen (2014)
10.1002/jbio.201000123
Optical biosensors to analyze novel biomarkers in oncology.
V. Donzella (2011)
Polymeric slot waveguide interferometers
Marianne Hiltunen (2014)
10.1039/C2RA21984K
Photonic resonant microcavities for chemical and biochemical sensing
V. Passaro (2013)
10.1016/J.OPTCOM.2011.01.004
Numerical demonstration of slow light tuning in slotted photonic crystal waveguide using microfluidic infiltration
J. Wu (2011)
10.1364/JOSAB.28.001266
Effects of shape and loading of optical nanoantennas on their sensitivity and radiation properties
Y. Zhao (2011)
10.1364/AO.53.005169
Optimization of multiple-slot waveguides for biochemical sensing.
Iman Khodadad (2014)
10.1109/IWASI.2011.6004705
Design of optimized SOI slot waveguides for homogeneous optical sensing in near infrared
F. De Leonardis (2011)
10.1364/JOSAA.28.000596
Design and optimization of waveguide sensitivity in slot microring sensors.
A. Kargar (2011)
10.1364/OL.37.000013
Reduction of scattering loss of silicon slot waveguides by RCA smoothing.
H. Sun (2012)
10.1007/S10762-010-9759-0
Investigation of Terahertz Wave Propagation Along Shielded Dielectric Multiple-Slot Waveguide
Zhihui Wang (2011)
10.1016/J.IJLEO.2013.07.088
Improvement of optical sensing performances of a double-slot-waveguide-based ring resonator sensor on silicon-on-insulator platform
G. Yuan (2014)
5 Chemical Sensors Based on Photonic Structures
B. Troia (2017)
10.1109/LPT.2013.2258333
Silicon Nitride Horizontal Air-Slot Microdisk Resonators With a Nanocrystal Si Emitting Layer
S. Lee (2013)
10.4028/www.scientific.net/AMR.710.404
A Multi-Slot-Waveguide-Based Ring Resonator Sensor on Silicon-on-Insulator Platform: Design and Simulation
L. Gao (2013)
10.1364/OE.26.019885
Surface sensing with integrated optical waveguides: a design guideline.
Johannes Milvich (2018)
10.1016/J.OPTCOM.2010.03.037
Wideband and low dispersion slow light in slotted photonic crystal waveguide
J. Wu (2010)
10.3390/s120302436
Optimizing SOI Slot Waveguide Fabrication Tolerances and Strip-Slot Coupling for Very Efficient Optical Sensing
V. Passaro (2012)
10.1109/NEMS.2010.5592217
Optical surface sensing by bent slot waveguides
A. Kargar (2010)
10.1002/ADOM.201801433
Optical Refractive Index Sensors with Plasmonic and Photonic Structures: Promising and Inconvenient Truth
Y. Xu (2019)
10.1364/OE.17.022571
Efficient fiber coupler for vertical silicon slot waveguides.
H. Sun (2009)
Horizontal Slot Waveguides for Silicon Photonics Back-End Integration
Maziar M. Naiini (2014)
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