Systemic Use Of A New Retinoid With And Without Local Dithranol Treatment In Generalized Psoriasis

giving little trouble undl 3 years ago. It then became more active, new lesions appeared, especially on her scalp, and the older ones enlarged. Topical steroids, combined with the use of Uvistat before light exposure, did not help her at all. She was started on chloroquin sulphate 200 mg twice daily, with initial relief. This had to be stopped after 5 weeks because of nausea, retching, photophobia, and weakness in the legs. After the chloroquine was stopped, she flared severely over the face and neck, and when seen in July she was both unsightly and depressed. She was given beta-carotene 50 mg three times daily, and had complete comfort within 2 weeks. This was maintained and all the lesions have regressed satisfactorily. She has been able to discondnue local steroids, and has had no sideeffects from the beta-carotene, which was stopped after 2 months.