Bacterial Biofilms: A Common Cause Of Persistent Infections.
John William Costerton, Philip S Stewart, E. Peter Greenberg
Published 1999 · Medicine, Biology
Download PDFAnalyze on Scholarcy
Bacteria that attach to surfaces aggregate in a hydrated polymeric matrix of their own synthesis to form biofilms. Formation of these sessile communities and their inherent resistance to antimicrobial agents are at the root of many persistent and chronic bacterial infections. Studies of biofilms have revealed differentiated, structured groups of cells with community properties. Recent advances in our understanding of the genetic and molecular basis of bacterial community behavior point to therapeutic targets that may provide a means for the control of biofilm infections.
This paper is referenced by
Bacterial Biofilm in Ventilator-Associated Pneumonia: A Clinical Concern
Elnaz Shahrokhi (2018)
Antibacterial activity of diacetylcurcumin against Staphylococcus aureus results in decreased biofilm and cellular adhesion
Janaína de Cássia Orlandi Sardi (2017)
Mechanism of cell integration on biomaterial implant surfaces in the presence of bacterial contamination.
Chongxia Yue (2015)
Potential and actual uses of zeolites in crop protection.
Caroline De Smedt (2015)
Biofilm formation in Candida glabrata: What have we learnt from functional genomics approaches?
Christophe d’Enfert (2016)
Interfacial separation of a mature biofilm from a glass surface - A combined experimental and cohesive zone modelling approach.
Ashkan Safari (2016)
Reusable nanoengineered surfaces for bacterial recruitment and decontamination.
Linnea K. Ista (2016)
Direct Laser Interference Patterning: Tailoring of Contact Area for Frictional and Antibacterial Properties
Andreas Rosenkranz (2016)
Molecular and physiological mechanisms underlying the antifungal and nutrient acquisition activities of beneficial microbes
Hanan R. Shehata (2016)
Eradication of Enterococcus faecalis Biofilms on Human Dentin
Eyal Rosen (2016)
The different ecological niches of enterotoxigenic E scherichia coli
Lucia Gonzales-Silès (2016)
Bugs on a Slippery Plane : Understanding the Motility of Microbial Pathogens with Mathematical Modelling.
Dmitri O. Pushkin (2016)
Biofilms: Flow disrupts communication
Paul Stoodley (2016)
Enhanced Performance and Mode of Action of a Novel Antibiofilm Hydrofiber® Wound Dressing
David Parsons (2016)
Preparation and evaluation of lipid polymer nanoparticles for eradicating H. pylori biofilm and impairing antibacterial resistance in vitro.
Jie Cai (2015)
Antimicrobial dressing efficacy against mature Pseudomonas aeruginosa biofilm on porcine skin explants.
Priscilla L Phillips (2015)
Recommendations on nuclear and multimodality imaging in IE and CIED infections
Paola Anna Erba (2018)
New insights into bacterial persistence in reactive arthritis.
D Astrauskiene (2007)
Metal-Adapted Bacteria Isolated From Wastewaters Produce Biofilms by Expressing Proteinaceous Curli Fimbriae and Cellulose Nanofibers
M Mosharaf (2018)
Towards the identification of the common features of bacterial biofilm development.
Iñigo Lasa (2006)
Escherichia coli GutM4 produces 2,5-diketopiperazines and inhibits human pathogens in vitro
Xichun Zhang (2017)
Werner Zimmerli (2004)
Biofilms as complex differentiated communities.
Paul Stoodley (2002)
Pathogen dynamics: Modeling and analysis of competition, organization, and vaccination
Glenn D. Young (2016)
Efficacy of Poly-Lactic-Co-Glycolic Acid Micro- and Nanoparticles of Ciprofloxacin Against Bacterial Biofilms.
Nicky Thomas (2016)
An optical microfluidic platform for spatiotemporal biofilm treatment monitoring
Young Wook Kim (2016)
Living biofouling-resistant membranes as a model for the beneficial use of engineered biofilms
Thammajun L. Wood (2016)
Infectious Chronic Rhinosinusitis
Sumit Bose (2016)
Temporin A Soaking in Combination with Intraperitoneal Linezolid Prevents Vascular Graft Infection in a Subcutaneous Rat Pouch Model of Infection with Staphylococcus epidermidis with Intermediate Resistance to Glycopeptides
Andrea Giacometti (2004)
Silver Nanocoating Technology in the Prevention of Prosthetic Joint Infection
J. B. Gallo (2016)
Colistin Resistance-Mediated Bacterial Surface Modification Sensitizes Phage Infection
Guijuan Hao (2019)
Tobacco use among Pre-university Students in Kannur, Kerala: A Cross-sectional Study
Sushrit A Neelopant (2016)See more