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Variation In Virulence Among Oculogenital Serovars Of Chlamydia Trachomatis In Experimental Genital Tract Infection

J I Ito, J M Lyons, L P Airo-Brown

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Seven different oculogenital serovars (D, E, F, G, H, I, and K) of Chlamydia trachomatis were inoculated intravaginally into CF-1 mice, and subsequent infection was monitored. The duration of infection was longest with serovars D and E. This may help to explain clinical surveys which demonstrate a high (50%) prevalence of these serovars. Furthermore, a comparison of the invasiveness of strains D and H demonstrated a much higher frequency of uterine horn infection with serovar D.