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Understanding And Addressing CLSI Breakpoint Revisions: A Primer For Clinical Laboratories

Romney M. Humphries, April N. Abbott, Janet A. Hindler

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The Clinical and Laboratory Standards Institute (CLSI) has revised several breakpoints since 2010 for bacteria that grow aerobically. In 2019, these revisions include changes to the ciprofloxacin and levofloxacin breakpoints for the Enterobacteriaceae and Pseudomonas aeruginosa , daptomycin breakpoints for Enterococcus spp., and ceftaroline breakpoints for Staphylococcus aureus .