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NK Cell Recognition.
Published 2005 · Biology, Medicine
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The integrated processing of signals transduced by activating and inhibitory cell surface receptors regulates NK cell effector functions. Here, I review the structure, function, and ligand specificity of the receptors responsible for NK cell recognition.
This paper references
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Major Histocompatibility Complex Class I–Recognizing Receptors Are Disease Risk Genes in Rheumatoid Arthritis
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Ly-49P Activates NK-Mediated Lysis by Recognizing H-2Dd 1
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A Novel Osteoblast-derived C-type Lectin That Inhibits Osteoclast Formation*
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Molecular Cloning of NKp46: A Novel Member of the Immunoglobulin Superfamily Involved in Triggering of Natural Cytotoxicity
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Mouse Ly-49D Recognizes H-2Dd and Activates Natural Killer Cell Cytotoxicity
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KIR2DL4 (CD158d) Genotype Influences Expression and Function in NK Cells1
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Domain Shuffling Has Been the Main Mechanism Forming New Hominoid Killer Cell Ig-Like Receptors1
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The human Ly-49L gene
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Survival advantage with KIR ligand incompatibility in hematopoietic stem cell transplantation from unrelated donors.
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p40 molecule regulates NK cell activation mediated by NK receptors for HLA class I antigens and TCR-mediated triggering of T lymphocytes.
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Natural killer cell cytolytic activity is inhibited by NKG2-A and activated by NKG2-C.
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CD3-negative natural killer cells express ε TCR as part of a novel molecular complex
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The immunomodulatory adapter proteins DAP12 and Fc receptor γ-chain (FcRγ) regulate development of functional osteoclasts through the Syk tyrosine kinase
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Ly-49W, an Activating Receptor of Nonobese Diabetic Mice With Close Homology to the Inhibitory Receptor Ly-49G, Recognizes H-2Dk and H-2Dd1
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CD161 (NKR-P1A) Costimulation of CD1d-dependent Activation of Human T Cells Expressing Invariant Vα24JαQ T Cell Receptor α Chains
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A p70 killer cell inhibitory receptor specific for several HLA-B allotypes discriminates among peptides bound to HLA-B*2705
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Human killer cell activatory receptors for MHC class I molecules are included in a multimeric complex expressed by natural killer cells.
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Cutting Edge: CD96 (Tactile) Promotes NK Cell-Target Cell Adhesion by Interacting with the Poliovirus Receptor (CD155)
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Cloning and characterization of the 2B4 gene encoding a molecule associated with non-MHC-restricted killing mediated by activated natural killer cells and T cells.
P. A. Mathew (1993)
Killer Cell Inhibitory Receptor Recognition of Human Leukocyte Antigen (HLA) Class I Blocks Formation of a pp36/PLC-γ Signaling Complex in Human Natural Killer (NK) Cells
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Biochemical Nature and Cellular Distribution of the Paired Immunoglobulin-like Receptors, PIR-A and PIR-B
Hiromi Kubagawa (1999)
Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2Kb
Julie Dam (2003)
Association of killer cell immunoglobulin-like receptors with scleroderma.
T. Momot (2004)
Genetic polymorphisms of killer cell immunoglobulin-like receptors are associated with susceptibility to psoriasis vulgaris.
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A Balance between Positive and Negative Signals in Cytotoxic Lymphocytes Regulates the Polarization of Lipid Rafts during the Development of Cell-Mediated Killing
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Alloantigen recognition by two human natural killer cell clones is associated with HLA-C or a closely linked gene.
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X-Linked Lymphoproliferative Disease 2b4 Molecules Displaying Inhibitory Rather than Activating Function Are Responsible for the Inability of Natural Killer Cells to Kill Epstein-Barr Virus–Infected Cells
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Crystal structure of a lectin-like natural killer cell receptor bound to its MHC class I ligand
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The Cytomegalovirus m155 Gene Product Subverts Natural Killer Cell Antiviral Protection by Disruption of H60–NKG2D Interactions
M. Lodoen (2004)
Cutting edge: expression of functional CD94/NKG2A inhibitory receptors on fetal NK1.1+Ly-49- cells: a possible mechanism of tolerance during NK cell development.
P. Sivakumar (1999)
Early stages in the development of human T, natural killer and thymic dendritic cells
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A 13-amino-acid motif in the cytoplasmic domain of FcγRIIB modulates B-cell receptor signalling
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CD94/NKG2-A inhibitory complex blocks CD16-triggered Syk and extracellular regulated kinase activation, leading to cytotoxic function of human NK cells.
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Activating interactions in human NK cell recognition: the role of 2B4‐CD48
H. Nakajima (1999)
Molecular characterization of a novel human natural killer cell receptor homologous to mouse 2B4.
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C1.7 antigen expression on CD8+ T cells is activation dependent: increased proportion of C1.7+CD8+ T cells in HIV-1-infected patients with progressing disease.
D. Peritt (1999)
Recognition of the Class Ib Molecule Qa-1b by Putative Activating Receptors Cd94/Nkg2c and Cd94/Nkg2e on Mouse Natural Killer Cells
R. Vance (1999)
The CD94 and NKG2‐A C‐type lectins covalently assemble to form a natural killer cell inhibitory receptor for HLA class I molecules
M. Carretero (1997)
IgG Fc receptors.
J. Ravetch (2001)
Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis
V. Groh (2003)
NKRP1A molecule is involved in transendothelial migration of CD4+ human T lymphocytes.
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