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Biologic Mechanisms Of The Protective Role Of Lutein And Zeaxanthin In The Eye.

N. Krinsky, J. Landrum, R. Bone
Published 2003 · Chemistry, Medicine

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The macular region of the primate retina is yellow in color due to the presence of the macular pigment, composed of two dietary xanthophylls, lutein and zeaxanthin, and another xanthophyll, meso-zeaxanthin. The latter is presumably formed from either lutein or zeaxanthin in the retina. By absorbing blue-light, the macular pigment protects the underlying photoreceptor cell layer from light damage, possibly initiated by the formation of reactive oxygen species during a photosensitized reaction. There is ample epidemiological evidence that the amount of macular pigment is inversely associated with the incidence of age-related macular degeneration, an irreversible process that is the major cause of blindness in the elderly. The macular pigment can be increased in primates by either increasing the intake of foods that are rich in lutein and zeaxanthin, such as dark-green leafy vegetables, or by supplementation with lutein or zeaxanthin. Although increasing the intake of lutein or zeaxanthin might prove to be protective against the development of age-related macular degeneration, a causative relationship has yet to be experimentally demonstrated.
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The effects of lutein and zeaxanthin on neural processing speed
E. R. Bovier (2013)
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Physicochemical properties and storage stability of lutein microcapsules prepared with maltodextrins and sucrose by spray drying.
P. Kuang (2015)
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Fabrication of chitosan nanoparticles with phosphatidylcholine for improved sustain release, basolateral secretion, and transport of lutein in Caco-2 cells.
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Genetic variation of yellow pigment and its components in foxtail millet (Setaria italica (L.) P. Beauv.) from different eco-regions in China
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Enzymatic Formation of β-Citraurin from β-Cryptoxanthin and Zeaxanthin by Carotenoid Cleavage Dioxygenase4 in the Flavedo of Citrus Fruit1[W][OPEN]
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Characteristics And Functions Of Lutein And Zeaxanthin Within The Human Retina
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The Effect of the Yellow Pigments on the Ocular Functions, the Effect on the Cognition, and the Development
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Macular Xanthophylls and Event-Related Brain Potentials among Overweight Adults and Those with Obesity.
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Isolation and Identification of Pathogens Causing Marigold (Tagetes erecta L.) Black Spot in Beijing, China
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Health Benefits of Polyphenols and Carotenoids in Age-Related Eye Diseases
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Obtenção de corante natural a partir de caroço de abacate (persea americana)
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Biomass and lutein productivity of Scenedesmus almeriensis: influence of irradiance, dilution rate and temperature
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Overexpression of CrtR-b2 (carotene beta hydroxylase 2) from S. lycopersicum L. differentially affects xanthophyll synthesis and accumulation in transgenic tomato plants
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Biochemical and Molecular Actions of Nutrients Xanthophylls and-Tocopherol Decrease UVB-Induced Lipid Peroxidation and Stress Signaling in Human Lens Epithelial Cells 1 , 2
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Effects of Egg Intake on Choline Metabolism and HDL Functionality in a Healthy Population
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Obesity, lutein metabolism, and age-related macular degeneration: a web of connections.
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Molecular characterisation of the human macula
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