Online citations, reference lists, and bibliographies.

Changes In Motor Unit Behavior Following Isometric Fatigue Of The First Dorsal Interosseous Muscle.

Lara Mcmanus, X. Hu, W. Rymer, M. Lowery, N. Suresh
Published 2015 · Medicine, Psychology

Cite This
Download PDF
Analyze on Scholarcy
The neuromuscular strategies employed to compensate for fatigue-induced muscle force deficits are not clearly understood. This study utilizes surface electromyography (sEMG) together with recordings of a population of individual motor unit action potentials (MUAPs) to investigate potential compensatory alterations in motor unit (MU) behavior immediately following a sustained fatiguing contraction and after a recovery period. EMG activity was recorded during abduction of the first dorsal interosseous in 12 subjects at 20% maximum voluntary contraction (MVC), before and directly after a 30% MVC fatiguing contraction to task failure, with additional 20% MVC contractions following a 10-min rest. The amplitude, duration and mean firing rate (MFR) of MUAPs extracted with a sEMG decomposition system were analyzed, together with sEMG root-mean-square (RMS) amplitude and median frequency (MPF). MUAP duration and amplitude increased immediately postfatigue and were correlated with changes to sEMG MPF and RMS, respectively. After 10 min, MUAP duration and sEMG MPF recovered to prefatigue values but MUAP amplitude and sEMG RMS remained elevated. MU MFR and recruitment thresholds decreased postfatigue and recovered following rest. The increase in MUAP and sEMG amplitude likely reflects recruitment of larger MUs, while recruitment compression is an additional compensatory strategy directly postfatigue. Recovery of MU MFR in parallel with MUAP duration suggests a possible role for metabolically sensitive afferents in MFR depression postfatigue. This study provides insight into fatigue-induced neuromuscular changes by examining the properties of a large population of concurrently recorded single MUs and outlines possible compensatory strategies involving alterations in MU recruitment and MFR.
This paper references
Firing rates of motor units in human vastus lateralis muscle during fatiguing isometric contractions.
A. Adam (2005)
Synchronization of low- and high-threshold motor units.
J. DeFreitas (2014)
Triphasic behavioral response of motor units to submaximal fatiguing exercise.
L. Dorfman (1990)
Neural compensation for muscular fatigue: evidence for significant force regulation in man.
R. Kirsch (1987)
High-yield decomposition of surface EMG signals
S. Nawab (2010)
Mechanisms underlying the reduction of isometric force in skeletal muscle fatigue.
H. Westerblad (1998)
Motor unit recruitment and rate coding in response to fatiguing shoulder abductions and subsequent recovery
B. Jensen (2000)
Experimental and modeling investigation of spectral compression of biceps brachii SEMG activity with increasing force levels.
D. Gabriel (2009)
EMG changes in human thenar motor units with force potentiation and fatigue.
C. Thomas (2006)
Estimating motor unit discharge patterns from high-density surface electromyogram
A. Holobar (2009)
Impaired motor unit
AK Suresh (2013)
Influence of proprioceptive feedback on the firing rate and recruitment of motoneurons.
C. D. De Luca (2012)
Motor unit synchronization during fatigue: described with a novel sEMG method based on large motor unit samples.
A. Holtermann (2009)
The fatigability of two agonistic muscles in human isometric voluntary submaximal contraction: an EMG study
B. Maton (1989)
Physiological characteristics of motor units in the brachioradialis muscle across fatiguing low-level isometric contractions.
Kristina M. Calder (2008)
Muscle fatigue: what, why and how it influences muscle function.
R. Enoka (2008)
Reliability of spike triggered averaging
WZ Rymer (2013)
Motor unit activity during long-lasting intermittent muscle contractions in humans
P. Christova (1998)
Task and fatigue effects on low-threshold motor units in human hand muscle.
R. Enoka (1989)
Relationship between firing rate and recruitment threshold of motoneurons in voluntary isometric contractions.
C. D. De Luca (2010)
Time course and properties of late adaptation in spinal motoneurones of the cat
Dr. D. Kernell (2004)
Reliability of spike triggered averaging of the surface electromyogram for motor unit action potential estimation.
Xiaogang Hu (2013)
Reflex origin for the slowing of motoneurone firing rates in fatigue of human voluntary contractions.
B. Bigland-Ritchie (1986)
Interpretation of EMG changes with fatigue: facts, pitfalls, and fallacies.
N. Dimitrova (2003)
Behaviour of a surface EMG based measure for motor control: motor unit action potential rate in relation to force and muscle fatigue.
L. Kallenberg (2008)
Inter-operator agreement in decomposition of motor unit firings from high-density surface EMG.
B. U. Kleine (2008)
Electromyogram median frequency, spectral compression and muscle fibre conduction velocity during sustained sub-maximal contraction of the brachioradialis muscle.
M. Lowery (2002)
The median frequency of the surface EMG power spectrum in relation to motor unit firing and action potential properties.
H. Hermens (1992)
isometric linear force ramp
A Holobar (2003)
Recruitment order of motor units in human vastus lateralis muscle is maintained during fatiguing contractions.
A. Adam (2003)
Analysis and Simulation of changes in EMG amplitude during high-level fatiguing contractions
M. Lowery (2003)
Reply to Farina and Enoka: The Reconstruct-and-Test Approach Is the Most Appropriate Validation for Surface EMG Signal Decomposition to Date
C. D. Luca (2011)
Fatigue of intermittent submaximal voluntary contractions: central and peripheral factors.
B. Bigland-ritchie (1986)
stimulation of rat soleus muscles
CA Hill (1989)
Motor unit behaviour and contractile changes during fatigue in the human first dorsal interosseus.
A. Carpentier (2001)
The fatigability of two agonistic muscles in human isometric voluntary submaximal contraction: an EMG study
D. Gamet (1989)
Behavior of motor units in human biceps brachii during a submaximal fatiguing contraction.
S. J. Garland (1994)
Impairment of neuromuscular propagation during human fatiguing contractions at submaximal forces.
A. Fuglevand (1993)
Spectral properties of the surface EMG do not characterize motor unit recruitment and rate coding.
Danny M. Pincivero (2008)
The relation between the surface electromyogram and muscular force.
H. Milner-Brown (1975)
Conduction velocity of quiescent muscle fibers decreases during sustained contraction.
M. Gazzoni (2005)
A new method for the extraction and classification of single motor unit action potentials from surface EMG signals
M. Gazzoni (2004)
Skeletal muscle fatigue: cellular mechanisms.
D. Allen (2008)
Assessment of validity of a high-yield surface electromyogram decomposition
X. Hu (2012)
Adjustments differ among low-threshold motor units during intermittent, isometric contractions.
D. Farina (2009)
Re-evaluation of muscle wisdom in the human adductor pollicis using physiological rates of stimulation.
A. Fuglevand (2003)
Effects of fatigue on motor unit firing rate versus recruitment threshold relationships.
M. Stock (2012)
Eccentric exercise does not affect common drive in the biceps brachii.
T. Beck (2012)
Electromyogram median frequency
MM Lowery (2008)
Correlation of mechanical action with directional tuning in the first dorsal interosseous (FDI)
N Suresh (2002)
Synchronization of lowand highthreshold motor units
JM Defreitas (2014)
The extraction of neural strategies from the surface EMG.
D. Farina (2004)
Accuracy assessment of a surface electromyogram decomposition system in human first dorsal interosseus muscle.
X. Hu (2014)
Use of surface EMG for studying motor unit recruitment during isometric linear force ramp.
J. Hogrel (2003)
Sarcoplasmic reticulum function and muscle contractile character following fatiguing exercise in humans.
C. A. Hill (2001)
Electromyogram and mechanomyogram changes in fresh and fatigued muscle during sustained contraction in men
F. Esposito (1998)
Models of recruitment and rate coding organization in motor-unit pools.
A. Fuglevand (1993)
Impaired motor unit control in paretic muscle post stroke assessed using surface electromyography: A preliminary report
Xiaogang Hu (2012)
Contralateral muscle activity and fatigue in the human first dorsal interosseous muscle.
M. Post (2008)
significant force regulation in man
BU Kleine (1893)
Increased sodium pump activity following repetitive stimulation of rat soleus muscles.
A. Hicks (1989)

This paper is referenced by
Beta-band Motor Unit Coherence and Nonlinear Surface EMG Features of the First Dorsal Interosseous Muscle Vary with Force.
Lara Mcmanus (2019)
Muscle fatigue increases beta-band coherence between the firing times of simultaneously active motor units in the first dorsal interosseous muscle.
Lara Mcmanus (2016)
Motor Unit Activity during Fatiguing Isometric Muscle Contraction in Hemispheric Stroke Survivors
Lara Mcmanus (2017)
Eight weeks of resistance training increases strength, muscle cross-sectional area and motor unit size, but does not alter firing rates in the vastus lateralis
Adam J Sterczala (2019)
Surface EMG and muscle fatigue: multi-channel approaches to the study of myoelectric manifestations of muscle fatigue.
Gazzoni Marco (2017)
Muscular strength and power are correlated with motor unit action potential amplitudes, but not myosin heavy chain isoforms in sedentary males and females.
T. Herda (2019)
Effects of Exertion Variability on the FDI Muscle Fatigue during Intermittent Contractions
Abdul Mathin Shaik (2018)
Motor unit action potential amplitudes and firing rates during repetitive muscle actions of the first dorsal interosseous in children and adults
Jonathan D. Miller (2019)
Adaptation of Fatigue Affected Changes in Muscle EMG Frequency Characteristics for the Determination of Training Load in Physical Therapy for Cancer Patients
Adam Hegedus (2019)
Non-Propagating Components of Surface Electromyogram Reflect Motor Unit Firing Rates
Luca Mesin (2019)
The effects of hypoxia on muscle deoxygenation and recruitment in the flexor digitorum superficialis during submaximal intermittent handgrip exercise
Hayley J. Nell (2020)
Reduced firing rates of high threshold motor units in response to eccentric overload
T. G. Balshaw (2017)
The Influence of Robotic Assistance on Reducing Neuromuscular Effort and Fatigue during Extravehicular Activity Glove Use
Kaci E. Madden (2017)
On the Power Spectrum of Motor Unit Action Potential Trains Synchronized With Mechanical Vibration
M. Romano (2018)
The effects of local forearm heating and cooling on motor unit properties during submaximal contractions.
Matt M Mallette (2020)
The exaction of motor unit action potential from multi-channel SEMG signals
He Jinbao (2015)
Intensity-dependent EMG response for the biceps brachii during sustained maximal and submaximal isometric contractions
Joshua C Carr (2016)
Contribution from motor unit firing adaptations and muscle coactivation during fatigue.
P. Contessa (2018)
Compensatory adjustments in motor unit behavior during fatigue differ for younger versus older men
J. A. Mota (2020)
Neural Contributions to Muscle Fatigue: From the Brain to the Muscle and Back Again.
J. Taylor (2016)
Comparisons Of Time To Task Failure And Muscle Activity For Two Different Submaximal Fatiguing Contractions
Sunggun Jeon (2018)
Anatomically accurate model of EMG during index finger flexion and abduction derived from diffusion tensor imaging
Diego Pereira Botelho (2019)
Muscle Fatigue Monitoring: Using HD-sEMG Techniques
Xiangyu Liu (2020)
Influence of dopaminergic treatment on resting elbow joint angle control mechanisms in patients with Parkinson's disease - a preliminary report.
Jarosław Marusiak (2018)
Effects of fatiguing, submaximal high‐ versus low‐torque isometric exercise on motor unit recruitment and firing behavior
Tyler W D Muddle (2018)
The compensatory interaction between motor unit firing behavior and muscle force during fatigue.
P. Contessa (2016)
A method for editing motor unit potential trains obtained by decomposition of surface electromyographic signals.
Robert I Kumar (2019)
Visualization of activated muscle area based on sEMG
Yangwei Cheng (2020)
Organization of the motor‐unit pool for different directions of isometric contraction of the first dorsal interosseous muscle
Yuming Lei (2018)
The Influence of Force Level and Motor Unit Coherence on Nonlinear Surface EMG Features Examined Using Model Simulation
Lara Mcmanus (2019)
Motor unit firing rates of the first dorsal interosseous differ between male and female children aged 8-10 years.
T. Herda (2019)
Semantic Scholar Logo Some data provided by SemanticScholar