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Ethnobotanical, Phytochemical, Pharmacological, And Toxicological Aspects Of Persicaria Hydropiper (L.) Delarbre

Akm Moyeenul Huq, Jamia Azdina Jamal, Johnson Stanslas
Published 2014 · Medicine
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Persicaria hydropiper (L.) Delarbre, belonging to Polygonaceae family, is a common weed found in most of the temperate countries including Bangladesh, China, Malaysia, and Japan. The plant is also referred to as “marsh pepper” or “smart weed.” It appears to be a useful herb with evidence-based medicinal properties. The present work addresses the botanical description, traditional uses, phytochemistry, pharmacology, and toxicology of P. hydropiper. All plant parts have been commonly used in the traditional systems of medicines. Flavonoids are the major group of phytochemical components followed by drimane-type sesquiterpenes and sesquiterpenoids, as well as phenylpropanoids. Different extracts and plant parts showed remarkable pharmacological activities including antioxidant, antibacterial, antifungal, antihelminth, antifeedant, cytotoxicity, anti-inflammatory, antinociceptive, oestrogenicity, antifertility, antiadipogenicity, and neuroprotection. Mutagenicity and acute and subchronic toxicities of the plant were also reported. P. hydropiper has tremendous medicinal properties that could further be investigated for the development of evidence-based herbal products.
This paper references
10.1016/j.mrfmmm.2013.04.009
Mutation research/fundamental and molecular mechanisms of mutagenesis: special issue: DNA repair and genetic instability.
Kandace J. Williams (2013)
10.1016/j.freeradbiomed.2010.02.034
Membrane cholesterol contents modify the protective effects of quercetin and rutin on integrity and cellular viability in oxidized erythrocytes.
José I Sánchez-Gallego (2010)
10.1016/0031-9422(80)85063-1
A potent cytotoxic warburganal and related drimane-type sesquiterpenoids from Polygonum hydropiper
Yoshiyasu Fukuyama (1980)
10.1515/znc-2008-3-410
Antifeedant Activity of Some Polygodial Derivatives
Luis Moreno-Osorio (2008)
10.7164/antibiotics.42.738
Structure-activity relationships for unsaturated dialdehydes. 3. Mutagenic, antimicrobial, cytotoxic, and phytotoxic activities of merulidial derivatives.
Heidrun Anke (1989)
10.1016/S1001-7844(10)60005-3
Root Extract of Polygonum Hydropiper Alters the Expression of Rat Uterine Protein Profile in Presence and Absence of Ovary in-situ during Periimplantation Period: An Evidence on SDS-PAGE
Pranjiv Goswami (2009)
Agricultural and biological chemistry
日本農芸化学会 (1961)
10.1055/s-2006-960114
Comparison of the antimicrobial and cytotoxic activities of twenty unsaturated sesquiterpene dialdehydes from plants and mushrooms.
Heidrun Anke (1991)
10.1016/S0031-9422(98)00426-9
Catechin production in cultured Polygonum hydropiper cells
Kanji Ono (1998)
S.Mhaskar, IndianMedicinal Plants, Periodical Experts Book Agency
E. Blatter (1998)
10.1039/C39760001013
Potent army worm antifeedants from the east African Warburgia plants
Isao Kubo (1976)
10.1055/s-1999-13981
In vitro antifungal susceptibilities of Candida albicans and other fungal pathogens to polygodial, a sesquiterpene dialdehyde.
Sang Hoon Lee (1999)
Natural dye-yielding plants and indigenous knowledge on dye preparation in Arunachal Pradesh, northeast India
Debajit Mahanta (2005)
10.1201/b11177-10
Medicinal Plants in China
Nathan Chukueke (2015)
10.1002/ps.3610
Comparative antifeedant activities of polygodial and pyrethrins against whiteflies (Bemisia tabaci) and aphids (Myzus persicae).
Neli Prota (2014)
Aphidicidal activity of some indigenous plant extracts against bean aphid Evidence-Based Complementary and Alternative Medicine 9
B C Das
IPR and traditional knowledge of Adi, Memba and Khamba tribes of upper siang distric, Arunachal Pradesh
R. K. Choudhury (2006)
10.1016/S1389-1723(00)87670-7
Depletion of glutathione as a cause of the promotive effects of polygodial, a sesquiterpene on the production of reactive oxygen species in Saccharomyces cerevisiae.
Kazuhiko Machida (1999)
10.1186/1746-4269-7-31
Ethnobotany of the Monpa ethnic group at Arunachal Pradesh, India
Nima D. Namsa (2011)
10.1016/j.bcp.2005.04.016
Inhibition of the mitochondrial ATP synthesis by polygodial, a naturally occurring dialdehyde unsaturated sesquiterpene.
María Victoria Castelli (2005)
10.1016/S0031-9422(02)00504-6
Antioxidant flavonoids from leaves of Polygonum hydropiper L.
Zhao Feng Peng (2003)
10.1007/BF00580088
Flavonoid aglycones ofPolygonum hydropiper
Kifakh S. Yusif (2004)
10.1007/s10340-008-0200-6
Aphidicidal activity of some indigenous plant extracts against bean aphid Aphis craccivora Koch (Homoptera: Aphididae)
Bidhan Chandra Das (2008)
Homoptera: Aphididae)
Koch Aphis Craccivora (2008)
ETHNOBOTANICAL INVENTORY OF MEDICINAL PLANTS FROM THE SOUTH-WEST OF ROMANIA
George Dan Mogosanu (2009)
10.1086/325163
Flora of North America
John G. Torrey (1969)
10.1248/bpb.30.595
Inhibitory compound of tyrosinase activity from the sprout of Polygonum hydropiper L. (Benitade).
Mitsuo Miyazawa (2007)
GRIN taxonomy for plants, Taxon: Persicaria hydropiper (L.) Delarbre
USDA (2014)
The estrogenic effects of Polygonumhydropiper root extract induce follicular recruitment and endometrial hyperplasia in female albino rats
A. Hazarika (2006)
10.1016/j.jpba.2010.08.026
Simultaneous determination of nine flavonoids in Polygonum hydropiper L. samples using nanomagnetic powder three-phase hollow fibre-based liquid-phase microextraction combined with ultrahigh performance liquid chromatography-mass spectrometry.
Xian Yang (2011)
10.1007/BF01013481
Activity of drimane antifeedants and related compounds against aphids, and comparative biological effects and chemical reactivity of (−)- and (+)-polygodial
Yoshinori Asakawa (2005)
10.1016/j.indcrop.2009.02.009
Antifeedant and growth inhibitory effects of extracts and drimanes of Drimys winteri stem bark against Spodoptera littoralis (Lep., Noctuidae)
Nelson Zapata (2009)
10.1111/j.1447-0578.2006.00136.x
Polygonum hydropiper crude root extract mimics estrogenic properties in females: Evidence of uterine protein profiles studied by sodium dodecyl sulfate polyacrylamide gel electrophoresis.
Ajit Hazarika (2006)
10.18519/JER/2008/V12/77757
Thin layer chromatographic fraction of root extract of Polygonum hydropiper induces vaginal epithelial cell maturation in adult ovariectomized albino rat
Pranjiv Goswami (2008)
여뀌 Persicaria hydropiper / 마디풀과
조태동 (2011)
Medicinal plants of Bangladesh: Chemical constituents and uses
Abdul Ghani (1998)
Antifungal activity of drimane sesquiterpenes from Drimys brasiliensis using bioassay-guided fractionation.
Angela Malheiros (2005)
Aphidicidal activity of some indigenous plant extracts against bean aphid Evidence-Based Complementary and Alternative Medicine 9 Aphis craccivoraKoch (Homoptera: Aphididae)
B. C. Das (2008)
10.1201/9781420040463
Handbook of Medicinal Herbs, Second Edition
J J Duke (1987)
10.1007/BF01962758
New norsesquiterpene aldehyde and sesquiterpene hemiacetal from the seed ofPolygonum hydropiper
Yoshinori Asakawa (2005)
10.1016/S0031-9422(00)81058-4
Drimane-type sesqui- and norsesquiterpenoids from polygonum hydropiper
Yoshiyasu Fukuyama (1985)
10.1016/S0024-3205(01)01387-X
Additional evidence for the anti-inflammatory and anti-allergic properties of the sesquiterpene polygodial.
Fernanda M da Cunha (2001)
Polygonum hydropiper
Flora of China (2014)
10.1271/bbb1961.52.1409
Mode of Action of Polygodial, an Antifungal Sesquiterpene Dialdehyde
Makoto Taniguchi (1988)
10.1016/j.contraception.2006.05.073
The estrogenic effects of Polygonum hydropiper root extract induce follicular recruitment and endometrial hyperplasia in female albino rats.
Ajit Hazarika (2006)
10.5860/choice.48-6278
The Plant List
Kew Royal Botanic Gardens (2013)
10.1002/ptr.3065
Persicarin from water dropwort (Oenanthe javanica) protects primary cultured rat cortical cells from glutamate-induced neurotoxicity.
Choong Je Ma (2010)
An ethnomedicinal inventory of knotweeds of Indian Himalaya
Ritesh Kumar Choudhary (2011)
10.1007/s11064-005-9033-3
The Sesquiterpenes Polygodial and Drimanial in vitro Affect Glutamatergic Transport in Rat Brain
Lucia Helena Martini (2005)
Assessment of mechanisms involved in antinociception caused by sesquiterpene polygodial.
Gelly Mendes (2000)
10.1021/jf00020a011
Antioxidative Substances in Leaves of Polygonum hydropiper
Hiroyuki Haraguchi (1992)
10.1016/0378-8741(91)90114-s
Can ethnopharmacology contribute to the development of anti-fertility drugs?
Xiao Pei-gen (1991)
10.2307/2423311
Flora of Missouri
Conrad Morton (1963)
Screening of Indian plants for antifertility activity.
Satish Kumar Garg (1978)
Australian National Botanic Gardens, Australian National Herbarium
Plants used against cancer. A survey.
Jonathan L. Hartwell (1970)
10.1016/0031-9422(83)83043-X
Hydropiperoside, a novel coumaryl glycoside from the root of Polygonum hydropiper
Yoshiyasu Fukuyama (1983)
Ethnobotany of theMonpa ethnic group atArunachal Pradesh, India
N. D. Namsa (2011)
10.1111/J.1654-1103.2012.01407.X
Review of ‘The Plant List, a working list of all plant species’
Jesse M. Kalwij (2012)
Drimane-type sesquiterpenes fromPolygonumhydropiper,”PlantaMedica
R. Sultana (2011)
The Glossary of Vietnamese Medicinal Plants and Items
D T Loi (2000)
Taxonomic Information, Phyto-chemical Constituents & Traditional Uses of Plants
Ethnobotanical Database of Bangladesh 3.1 (2013)
10.1016/0027-5107(92)90237-V
Structure-activity relationships for unsaturated dialdehydes. 6. The mutagenic activity of 11 compounds in the V79/HGPRT assay.
Paloma Morales (1992)
10.1002/ptr.4690
Antiproliferative activity of polygonaceae species from the Carpathian Basin against human cancer cell lines.
Ildikó Lajter (2013)
10.1007/s12272-001-2133-y
New phenylpropanoid esters of sucrose from Polygonum hydropiper and their antioxidant activity
Phan Van Kiem (2008)
Polygonum hydropiper
Flora of Missouri (2014)
Polygodial , an antifungal potentia
M. Taniguchi (1988)
10.1016/S0367-326X(02)00239-3
Antinociceptive activity of Polygonum hydropiper.
Eva Rahman (2002)
10.1128/AAC.44.7.1943-1953.2000
Effect of Polygodial on the Mitochondrial ATPase of Saccharomyces cerevisiae
Christopher S. Lunde (2000)
Loi,TheGlossary of VietnameseMedicinal Plants and Items, Hanoi Medicine Publishing
D T. (2000)
List of Existing Food Additives
(2014)
10.1016/S0031-9422(00)85513-2
Polygonolide, an isocoumarin from Polygonum hydropiper possessing anti-inflammatory activity
Takuya Furuta (1986)
10.1016/S0024-3205(98)00285-9
Anti-hyperalgesic properties of the extract and of the main sesquiterpene polygodial isolated from the barks of Drymis winteri (Winteraceae).
Gelly Mendes (1998)
10.1021/np9601622
Effect of Polygonum hydropiper sulfated flavonoids on lens aldose reductase and related enzymes.
Hiroyuki Haraguchi (1996)
Anthelmintic and Antiproliferative activity of aerial parts of Persicaria hydropiper
Md. Obayed Raihan (2012)
10.1016/j.neuropharm.2003.10.008
Evidence for the involvement of vanilloid receptor in the antinociception produced by the dialdeydes unsaturated sesquiterpenes polygodial and drimanial in rats
Eunice André (2004)
10.1016/j.fct.2006.01.020
Subchronic toxicity study of water pepper extract in F344 rats.
Keiko Kuroiwa (2006)
Polygonum hydropiper L. marshpepper knotweed
USDA (2014)
10.2307/2257819
Polygonum Hydropiper L.
J. Timson (1966)
10.1021/np50055a002
Polygodial, an antifungal potentiator.
Isao Kubo (1988)
10.1071/ch9620322
The Structure of Polygodial: A New Sesquiterpene Dialdehyde from Polygonum hydropiper L
Cs Barnes (1962)
10.1016/S1001-7844(12)60011-X
Chromatographic Fraction of Polygonum hydropiper Root Modulates the Expression of Transforming Growth Factor-βI (TGF-βI) in Rat Uterus during Days 2-6 of Gestation
Pranjiv Goswami (2011)
10.1038/137255c0
A Dictionary of the Economic Products of the Malay Peninsula
Isaac Henry Burkill (1936)
10.1016/S0014-2999(97)01570-7
Action of polygodial, a sesquiterpene isolated from Drymis winteri, in the guinea-pig ileum and trachea 'in vitro'.
Mariem El Sayah (1998)
The Encyclopedia of Medicinal Plants, Dorling Kindersley
A. Chevallier (1996)
10.1016/j.chroma.2010.12.020
Two-dimensional thin-layer chromatography of selected Polygonum sp. extracts on polar-bonded stationary phases.
Mirosław A. Hawrył (2011)
10.5860/choice.36-3327
Native American Ethnobotany
Daniel E. Moerman (1998)
Plants used against cancer. A survey. [Continued.].
Jonathan L. Hartwell (1970)
10.5860/choice.34-3624
Encyclopedia of medicinal plants
Jorge D. Pamplona Roger (1998)
10.2307/3244038
PLANTS USED AGAINST CANCER
J L Hartwell (1989)
10.1055/s-0030-1271178
Drimane-type sesquiterpenes from Polygonum hydropiper.
Rajia Sultana (2011)
An Ethnobotanical Survey and Pharmacological Evaluation of Medicinal Plants used by the Garo Tribal Community living in Netrakona district , Bangladesh
Mohammed Rahmatullah (2010)
10.2307/2483268
Flora of the British Isles
Arthur Roy Clapham (1962)
10.1111/j.1399-3054.1994.tb03028.x
Occurrence of polygodial in plant organs and tissue culture of Polygonum hydropiper
Marc J. M. Hagendoorn (1994)
10.1016/j.bmc.2005.07.023
Multifunctional action of antifungal polygodial against Saccharomyces cerevisiae: involvement of pyrrole formation on cell surface in antifungal action.
Ken-Ichi Fujita (2005)
10.1016/j.jep.2011.12.003
In vitro and in vivo anti-inflammatory activities of Polygonum hydropiper methanol extract.
Yanyan Yang (2012)
10.1016/S0031-9422(00)90632-0
Antioxidative sulphated flavonoids in leaves of Polygonum hydropiper
Akira Yagi (1994)
10.1007/978-3-642-77004-3_18
Polygonum hydropiper L. (Water Pepper): In Vitro Culture and the Production of the Aphid-Antifeedant Polygodial
Derek V. Banthorpe (1993)
A handbook of medicinal herbs
Dhananjay J. Deshpande (2016)
Indian Medicinal Plants
Bettina Evers (1875)
10.1002/ptr.3469
Persicaria hydropiper (L.) spach and its flavonoid components, isoquercitrin and isorhamnetin, activate the Wnt/β-catenin pathway and inhibit adipocyte differentiation of 3T3-L1 cells.
Soung-Hoon Lee (2011)
10.3109/13880200902902471
Antimicrobial activity of confertifolin from Polygonum hydropiper
Veeramuthu Duraipandiyan (2010)
10.1016/J.LWT.2011.11.021
LC–DAD–ESIMS/MS characterization of antioxidant and anticholinesterase constituents present in the active fraction from Persicaria hydropiper
Noor Haslinda Noor Hashim (2012)
Medicinal Plants of the Santal Tribe Residing in Rajshahi District, Bangladesh
M. Shahidullah (2009)
Medicinal Plants of Bangladesh
M Yusuf (2009)
Chinese Materia Medica: Vegetable Kingdom
F P Smith (1979)
Burkill,ADictionary of the Economic Products of theMalay Peninsula, vol. 2, Ministry of Agriculture and Co-operatives
I H. (1966)
10.1002/ptr.1777
Antibacterial activity of polygodial.
Isao Kubo (2005)



This paper is referenced by
10.11648/J.AJPN.20160402.12
Evaluation of Nootropic Activity of Persicaria flaccida on Cognitive Performance, Brain Antioxidant Markers and Acetylcholinesterase Activity in Rats: Implication for the Management of Alzheimer’s Disease
Md. Sahab Uddin (2016)
10.1016/j.ijpara.2017.11.009
Bioassay-guided isolation of three anthelmintic compounds from Warburgia ugandensis Sprague subspecies ugandensis, and the mechanism of action of polygodial.
Maoxuan Liu (2018)
10.1016/j.ejphar.2018.03.029
Polygodial analog induces apoptosis in LNCaP prostate cancer cells
Subramanyam Dasari (2018)
10.1007/978-3-030-03344-6_23
Multiple Uses of Some Important Aquatic and Semiaquatic Medicinal Plants
Muhammad Aasim (2019)
10.1186/s40816-017-0056-5
Evaluation of sedative and anxiolytic activities of methanol extract of leaves of Persicaria hydropiper in mice
Md. Shahed-Al-Mahmud (2017)
10.5812/jjnpp.64788
Chemical Constituents of Persicaria sagittata (L.) H.Gross: Antioxidant Activity and Chemotaxonomy Significance
Idin Sahidin (2019)
10.1080/14786419.2016.1269094
Biological evaluation of phytoconstituents from Polygonum hydropiper
Hong Xiao (2017)
10.3390/molecules23071739
Phytochemical Screening of Quaking Aspen (Populus tremuloides) Extracts by UPLC-QTOF-MS and Evaluation of their Antimicrobial Activity
Annabelle St-Pierre (2018)
10.15171/JHP.2019.18
Collagenase inhibition by water-pepper (Polygonum hydropiper L.) sprout extract
Tomoaki Kawaguchi (2019)
10.1016/J.CHNAES.2019.05.017
The quest for some novel antifertility herbals used as male contraceptives in district Shangla, Pakistan
Wajid Zaman (2020)
10.3389/fmicb.2016.01394
Beneficial Effects of Spices in Food Preservation and Safety
Davide Gottardi (2016)
10.1007/s10298-016-1088-6
Persicaire ou poivre d’eau Persicaria hydropiper (L.) Delarbre (Polygonaceae)
Kamel Ghédira (2016)
10.3389/fphar.2018.01192
Naturally Occurring Acetylcholinesterase Inhibitors and Their Potential Use for Alzheimer's Disease Therapy
Thaiane Coelho dos Santos (2018)
Phytochemical screening of Goniothalamus sesquipedalis
Rafiqul Hasan Khan (2018)
10.1155/2016/7832120
Appraisals of Bangladeshi Medicinal Plants Used by Folk Medicine Practitioners in the Prevention and Management of Malignant Neoplastic Diseases
Md Nur Kabidul Azam (2016)
Study on medicinal uses of Persicaria and Rumex species of polygonaceae family
Tamanna Sharmin Tonny (2017)
10.1155/2014/695291
Phenolic Profiling and Evaluation of Contraceptive Effect of the Ethanolic Extract of Salsola imbricata Forssk. in Male Albino Rats
Naglaa Gamil Shehab (2014)
10.3390/molecules23082053
Biopesticide Activity from Drimanic Compounds to Control Tomato Pathogens
Iván J Montenegro (2018)
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