Online citations, reference lists, and bibliographies.

Assessment Of Hip Fracture Risk Using Cross-Section Strain Energy Determined By QCT-Based Finite Element Modeling

Hossein Kheirollahi, Yunhua Luo
Published 2015 · Medicine, Biology

Cite This
Download PDF
Analyze on Scholarcy
Share
Accurate assessment of hip fracture risk is very important to prevent hip fracture and to monitor the effect of a treatment. A subject-specific QCT-based finite element model was constructed to assess hip fracture risk at the critical locations of femur during the single-leg stance and the sideways fall. The aim of this study was to improve the prediction of hip fracture risk by introducing a novel failure criterion to more accurately describe bone failure mechanism. Hip fracture risk index was defined using cross-section strain energy, which is able to integrate information of stresses, strains, and material properties affecting bone failure. It was found that the femoral neck and the intertrochanteric region have higher fracture risk than other parts of the femur, probably owing to the larger content of cancellous bone in these regions. The study results also suggested that women are more prone to hip fracture than men. The findings in this study have a good agreement with those clinical observations reported in the literature. The proposed hip fracture risk index based on strain energy has the potential of more accurate assessment of hip fracture risk. However, experimental validation should be conducted before its clinical applications.
This paper references
and W
R. Vasu (1983)
and K
N. Nakamura (1992)
10.1016/j.bone.2014.04.007
Analysis of strength and failure pattern of human proximal femur using quantitative computed tomography (QCT)-based finite element method.
Majid Mirzaei (2014)
and W
J. C. Lotz (1991)
and A
S. J. Jacobsen (1990)
10.1007/BF02344865
Measurement of femoral neck anteversion in 3D. Part 2:3D modelling method
J. S. Kim (2006)
and T
S. N. Robinovitch (1991)
Epidemiology and Rehabilitation of Hip Fractures in the Geriatric Population.
V. Trikha (2005)
10.1016/S0266-3538(96)00145-5
A strain-energy based failure criterion for non-linear analysis of composite laminates subjected to biaxial loading
W. E. Wolfe (1998)
10.1002/jbmr.1651
To FRAX or not to FRAX.
Michael R Mcclung (2012)
and A
E. Vega (1991)
10.5040/9781474284028.0024
S
A. Kumar (1824)
10.1177/0954411911424975
A preliminary dual-energy X-ray absorptiometry-based finite element model for assessing osteoporotic hip fracture risk
Y. Luo (2011)
10.1370/afm.602
Validation of a 4-Item Score Predicting Hip Fracture and Mortality Risk Among Elderly Women
Daniel Albertsson (2007)
10.1007/PL00004148
World-wide Projections for Hip Fracture
B. Gullberg (1997)
10.1080/13642537.2013.793029
Failure
Nic Bayley (1890)
and A
D. Testi (1999)
10.1016/S0169-2607(99)00007-3
Risk of fracture in elderly patients: a new predictive index based on bone mineral density and finite element analysis.
D. Testi (1999)
10.2106/JBJS.I.00919
The assessment of fracture risk.
A. Unnanuntana (2010)
10.1016/j.bone.2009.04.241
Prediction of proximal femur strength using a CT-based nonlinear finite element method: differences in predicted fracture load and site with changing load and boundary conditions.
M. Bessho (2009)
andM
J. D. Michelson (1995)
andW
S. L. Greenspan (1994)
10.4103/0019-5413.73656
Epidemiology of hip fracture: Worldwide geographic variation
D. Dhanwal (2011)
and S
K. K. Nishiyama (2013)
10.1115/1.2895414
Prediction of femoral impact forces in falls on the hip.
S. Robinovitch (1991)
10.1016/j.ejrad.2008.04.061
Assessment of fracture risk.
J. Kanis (2009)
and E
E. Sariali (2009)
10.1136/bmj.39428.470752.AD
Shifting the focus in fracture prevention from osteoporosis to falls
T. Järvinen (2008)
10.1016/S0002-9343(97)90023-1
The socioeconomic burden of fractures: today and in the 21st century.
O. Johnell (1997)
The elastic moduli of bone
W. C. van Buskirk (1981)
BioMed Research International
and W
Y. Luo (2013)
Assessment of fracture risk,”European
J. A. Kanis (2009)
10.1007/BF01880448
Bone mineral density in patients with cervical and trochanteric fractures of the proximal femur
E. Vega (2005)
and H
J. H. Keyak (1997)
and E
J. A. Kanis (2009)
10.1002/JBMR.5650091208
Trochanteric bone mineral density is associated with type of hip fracture in the elderly.
S. Greenspan (1994)
10.1016/S0020-1383(99)00120-5
Strain gauges used in the mechanical testing of bones. Part I: Theoretical and technical aspects.
J. Cordey (1999)
10.1002/jor.1100120610
Estimation of material properties in the equine metacarpus with use of quantitative computed tomography.
C. Les (1994)
10.1016/J.JBIOMECH.2007.09.009
Subject-specific finite element models implementing a maximum principal strain criterion are able to estimate failure risk and fracture location on human femurs tested in vitro.
E. Schileo (2008)
10.1007/s007740050072
Fracture simulation of the femoral bone using the finite-element method: How a fracture initiates and proceeds
T. Ota (1999)
and R
T. Ota (1999)
Epidemiology of Hip Fractures Among the Elderly: Risk Factors for Fracture Type
J. Michelson (1995)
10.1515/9783111548050-035
Z
Axel M. Gressner (2012)
10.1016/S0140-6736(05)61503-6
T
D. Davies (1998)
[Osteometry of the femora in Turkish individuals: a morphometric study in 114 cadaveric femora as an anatomic basis of femoral component design].
B. Atilla (2007)
Field guide to fracture management
R. Birrer (2005)
and C
J. H. Keyak (1990)
Mechanics of fracture initiation and propagation
G. Sih (1990)
10.1002/cnm.2548
Precision study of DXA-based patient-specific finite element modeling for assessing hip fracture risk.
Yunhua Luo (2013)
Heterogeneity of hip fracture: age
M. R. Karagas (1996)
and M
M. Mirzaei (2009)
Fixing Hip Fractures
(2015)
10.1097/nor.0000000000000200
Hip Fractures
L. Altizer (2005)
10.1016/0141-5425(90)90022-F
Automated three-dimensional finite element modelling of bone: a new method.
J. Keyak (1990)
and H
D. Marshall (1996)
andM
E. Schileo (2008)
10.1016/j.jbiomech.2009.04.042
On prediction of the strength levels and failure patterns of human vertebrae using quantitative computed tomography (QCT)-based finite element method.
Majid Mirzaei (2009)
10.1016/S0020-1383(99)00122-9
Strain gauges used in the mechanical testing of bones. Part III: Strain analysis, graphic determination of the neutral axis.
J. Cordey (1999)
and P
T.L.N. Järvinen (2008)
andM
B. Atilla (2007)
10.1016/0021-9290(93)90059-N
Trabecular bone modulus and strength can depend on specimen geometry.
T. M. Keaveny (1993)
10.5435/00124635-199405000-00002
Hip Fractures: I. Overview and Evaluation and Treatment of Femoral‐Neck Fractures
K. Koval (1994)
10.1016/j.bone.2012.01.012
Ct-based finite element models can be used to estimate experimentally measured failure loads in the proximal femur.
Janne E. M. Koivumäki (2012)
and W
T. M. Keaveny (1993)
The elastic moduli of bone
W C Van Buskirk (1981)
and A
C. M. Les (1994)
andW
J. C. Lotz (1991)
10.1115/1.2895413
Fracture prediction for the proximal femur using finite element models: Part II--Nonlinear analysis.
J. C. Lotz (1991)
10.1016/j.ejrad.2008.04.064
Advances in osteoporosis imaging.
J. Bauer (2009)
10.1002/JBMR.5650090713
Geometric structure of the femoral neck measured using dual-energy x-ray absorptiometry.
T. Yoshikawa (1994)
10.1016/0021-9290(94)90056-6
Predicting the compressive mechanical behavior of bone.
T. Keller (1994)
10.1016/S0021-9290(99)00152-9
Prediction of femoral fracture load using finite element models: an examination of stress- and strain-based failure theories.
J. Keyak (2000)
10.1007/BF02344864
Measurement of femoral neck anteversion in 3D. Part 1: 3D imaging method
J. S. Kim (2006)
10.1136/bjo.46.11.704
A and V
R. Stephenson (1962)
10.1016/J.IJSOLSTR.2012.01.015
An extended strain energy density failure criterion by differentiating volumetric and distortional deformation
Yujie Wei (2012)
10.1007/s10439-012-0514-7
Relationships Between Femoral Strength Evaluated by Nonlinear Finite Element Analysis and BMD, Material Distribution and Geometric Morphology
He Gong (2012)
10.1115/1.2895412
Fracture prediction for the proximal femur using finite element models: Part I--Linear analysis.
J. C. Lotz (1991)
10.1515/9783111548050-035
Z
Axel M. Gressner (2012)
10.1515/9783111548050-024
M
M. Sankar (1824)
10.1007/BF00035493
Strain-energy-density factor applied to mixed mode crack problems
G. Sih (1974)
10.1016/8756-3282(95)00490-4
Are the etiologies of cervical and trochanteric hip fractures different?
C. Mautalen (1996)
10.1016/S8756-3282(03)00214-X
On the importance of geometric nonlinearity in finite-element simulations of trabecular bone failure.
J. Stölken (2003)
10.1093/oxfordjournals.aje.a008800
Heterogeneity of hip fracture: age, race, sex, and geographic patterns of femoral neck and trochanteric fractures among the US elderly.
M. Karagas (1996)
10.1016/b978-0-12-384931-1.00016-7
P
J. Lackie (2013)
10.1007/s10439-010-0196-y
Robust QCT/FEA Models of Proximal Femur Stiffness and Fracture Load During a Sideways Fall on the Hip
D. Dragomir-Daescu (2010)
10.2105/AJPH.80.7.871
Hip fracture incidence among the old and very old: a population-based study of 745,435 cases.
S. Jacobsen (1990)
10.1016/J.BONE.2004.11.012
Low BMD is less predictive than reported falls for future limb fractures in women across Europe: results from the European Prospective Osteoporosis Study.
S. Kaptoge (2005)
10.1115/1.3138429
Evaluation of bone cement failure criteria with applications to the acetabular region.
R. Vasu (1983)
10.1007/s00198-008-0785-x
Targeted exercises against hip fragility
R. Nikander (2008)
10.1016/S0021-9290(97)00123-1
Prediction of femoral fracture load using automated finite element modeling.
J. Keyak (1997)
10.1016/j.arth.2008.04.031
Three-dimensional hip anatomy in osteoarthritis. Analysis of the femoral offset.
E. Sariali (2009)
10.1001/jama.1989.03420070075034
'Senile' osteoporosis reconsidered.
N. Resnick (1989)
10.1016/S0266-3538(01)00203-2
A strain-energy-based non-linear failure criterion: comparison of numerical predictions and experimental observations for symmetric composite laminates
T. Butalia (2002)
10.1016/j.jbiomech.2013.02.025
Proximal femur bone strength estimated by a computationally fast finite element analysis in a sideways fall configuration.
K. Nishiyama (2013)
Sih, Mechanics of Fracture Initiation and Propagation, Springer, Dordrecht
G C. (1991)
and C
D. K. Dhanwal (2011)
10.1016/0021-9290(75)90075-5
The elastic and ultimate properties of compact bone tissue.
D. Reilly (1975)
10.1016/0378-5122(96)81789-0
Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures.
D. Marshall (1996)
10.1002/JBMR.5650070705
Bone mineral density in the proximal femur and hip fracture type in the elderly.
N. Nakamura (1992)
10.1007/s00198-009-0920-3
Excess mortality following hip fracture: a systematic epidemiological review
B. Abrahamsen (2009)



This paper is referenced by
10.1155/2019/6067952
The Influence of Geometry of Implants for Direct Skeletal Attachment of Limb Prosthesis on Rehabilitation Program and Stress-Shielding Intensity
Piotr Prochor (2019)
10.1007/S40846-017-0266-9
Understanding Hip Fracture by QCT-Based Finite Element Modeling
Hossein Kheirollahi (2017)
Computational and mathematical modeling of medical images : advanced methods and applications in translational myology and surgical planning
Kyle Joseph Edmunds (2017)
10.1186/s40634-016-0072-2
Quantitative Computed Tomography (QCT) derived Bone Mineral Density (BMD) in finite element studies: a review of the literature
N. Knowles (2016)
10.1115/1.4042172
The Effect of Inhomogeneous Trabecular Stiffness Relationship Selection on Finite Element Outcomes for Shoulder Arthroplasty.
Jacob M. Reeves (2019)
Participant-Specific Modelling of the Proximal Femur during Lateral Falls: A Mechanistic Evaluation of Risk Factors
Steven P. Pretty (2019)
10.1155/2017/4791706
Corrigendum to “Assessment of Hip Fracture Risk Using Cross-Section Strain Energy Determined by QCT-Based Finite Element Modeling”
Hossein Kheirollahi (2017)
10.1016/j.jbiomech.2018.08.003
Linear and nonlinear analyses of femoral fractures: Computational/experimental study.
Majid Mirzaei (2018)
10.1115/1.4040122
Methods for Post Hoc Quantitative Computed Tomography Bone Density Calibration: Phantom-Only and Regression.
Jacob M. Reeves (2018)
10.1007/978-3-319-51671-4_9
Measurements of Hip Fracture Risk
Yunhua Luo (2017)
Semantic Scholar Logo Some data provided by SemanticScholar