Online citations, reference lists, and bibliographies.
← Back to Search

Role Of Atrial Natriuretic Peptide In Nocturnal Polyuria In Elderly Males

P. Carter, A. Cannon, A. Mcconnell, P. Abrams
Published 1999 · Medicine

Save to my Library
Download PDF
Analyze on Scholarcy
Share
Objectives: To demonstrate nocturnal polyuria objectively and to assess the role of atrial natriuretic peptide (ANP) in healthy elderly males with and without nocturnal polyuria (NP). Patients and Methods: 31 healthy elderly men known to have NP (passing more than 33% of their 24-hour urine output during an 8-hour period overnight) and 12 controls without NP were invited to take part in the study. Blood and urine samples were collected at 4-hourly intervals in order to measure urine output, serum and urine electrolytes and osmolality as well as serum cortisol, renin, aldosterone, arginine vasopressin (AVP) and ANP. Results: 26 men with NP and 8 controls agreed to take part in the study. Subjects with NP were found to have a diuresis and natriuresis as well as a significant increase in ANP overnight compared to the control group. There was no difference in the other parameters between the 3 groups, with the exception of aldosterone and AVP. Conclusions: This study has shown a group of subjects with increased natriuresis and diuresis overnight, associated with an increase in ANP. It is possible that subclinical cardiac failure causes an increase in ANP therefore causing nocturnal urinary symptoms and this theory needs further exploration.
This paper references
Vasoactive peptides and substrates and their relation to protein handling by the kidney.
R. Rosas (1963)
10.1038/KI.1975.120
Effect on aging on plasma renin and aldosterone in normal man.
P. Weidmann (1975)
10.1136/bmj.2.5530.1620
Observations on some diurnal rhythms in depressive illness.
A. Elithorn (1966)
10.3109/07420528509055889
Circadian rhythms of plasma renin activity and aldosterone: changes related to age, sex, recumbency and sodium restriction. Chronobiologic specification for reference values.
P. Cugini (1985)
10.1042/CS0730489
Diurnal change in plasma atrial natriuretic peptide concentrations.
A. Richards (1987)
Circadian time structure in the endocrine system of elderly subjects.
S. Sensi (1987)
10.1097/00006842-197802000-00006
Secretion of Hormones Influencing Water and Electrolyte Balance (Antidiuretic Hormone, Aldosterone, Prolactin) during Sleep in Normal Adult Men
R. Rubin (1978)
10.1210/JCEM-42-1-20
A kinetic study of plasma renin and aldosterone during changes of posture in man.
J. Sassard (1976)
Observations on Some of the Daily Changes of the Urine
W. Roberts (1860)
10.1136/bmj.287.6406.1665
Patterns of urine flow and electrolyte excretion in healthy elderly people.
J. Kirkland (1983)
10.1136/jnnp.37.6.677
Basis of nocturnal polyuria in patients with autonomic failure
C. Wilcox (1974)
10.1210/JCEM-38-3-489
Plasma aldosterone concentration in normal subjects from infancy to adulthood.
A. Kowarski (1974)
10.1093/GERONT/28.1.99
Nocturia in the elderly.
J. Barker (1988)
10.1016/s0021-9258(18)77070-1
Changes in the composition of urine brought about by sleep and other factors
G. E. Simpson (1929)
Urinary symptoms in older people
JS Milne (1972)
10.1172/JCI105543
Postural augmentation of plasma renin activity and aldosterone excretion in normal people.
E. L. Cohen (1967)
Neph - roptosis with nocturnal polyuria
Donaldson IML (1967)
10.1172/JCI106974
Studies of the control of plasma aldosterone concentration in normal man. I. Response to posture, acute and chronic volume depletion, and sodium loading.
G. Williams (1972)
Perception of light and the maintenance of human renal diurnal rhythms
MC Lobban (1967)
Tredre BE: Observation on some diurnal rhythms in depressive illness
A Elithorn (1963)
Urinary tract infection in the aged: An epidemiological study
LB Sourander (1966)
10.1016/0002-9343(67)90171-4
Nephroptosis with nocturnal polyuria.
I. Donaldson (1967)
Tredre BE: Perception of light and the maintenance of human renal diurnal rhythms
MC Lobban (1967)
The role of nocturnal polyuria in nocturnal urinary symptoms in the healthy elderly male
P. Carter (1992)
10.1210/JCEM-41-2-332
Diurnal variation of plasma vasopressin in man.
C. George (1975)
Mitteness LS: Nocturia in the elderly
JC Barker (1988)
Frequency volume charts revealing physiological abnormalities
NJR George (1983)
10.1038/199667A0
Diurnal Rhythms of Electrolyte Excretion in Depressive Illness
M. Lobban (1963)
Effect of aging on renin activity and aldosterone excretion.
M. Crane (1976)
10.1111/J.0954-6820.1983.TB19332.X
Age and the renin-angiotensin system.
P. Skott (1983)
quency volume charts revealing physiological abnormalities
George NJR (1981)
10.1111/j.1532-5415.1971.tb02579.x
DYSURIA IN OLD AGE *
J. Brocklehurst (1971)
10.1113/jphysiol.1951.sp004593
Diurnal rhythm in urine flow
J. N. Mills (1951)
10.1172/JCI105464
A diurnal rhythm in plasma renin activity in man.
R. Gordon (1966)
10.1136/bmj.293.6543.353
The effect of desmopressin on nocturnal polyuria, overnight weight loss, and morning postural hypotension in patients with autonomic failure.
C. Mathias (1986)
Postural augmentation of plasma renin activity and aldosterone during changes of posture in man
EL Cohen (1967)
Effect of aging on renin activity and aldosterone excretion.
Crane Mg (1976)
10.1001/ARCHINTE.1977.03630220056014
Age and the renin-aldosterone system.
R. Noth (1977)



This paper is referenced by
10.1111/j.1442-2042.2008.02248.x
Fluid control in elderly patients with nocturia
O. Natsume (2009)
10.1016/S0022-5347(05)64472-2
Normal values and determinants of circadian urine production in older men: a population based study.
M. Blanker (2002)
10.2217/14750708.5.5.667
Desmopressin for the treatment of adult nocturia
H. Hashim (2008)
10.1016/J.UROLOGY.2005.09.037
Multifactorial nature of male nocturia.
Shyh-Chyi Chang (2006)
10.1016/j.jash.2012.12.004
Nocturia in arterial hypertension: a prevalent, underreported, and sometimes underestimated association.
C. Feldstein (2013)
10.1002/14651858.CD004669.PUB2
Conservative management of nocturia in adults
J. Reynard (2016)
10.1111/j.1442-2042.2007.01847.x
Diuretic pattern in adults with nocturnal polyuria: The possible contribution of blood pressure to the worsening of nocturnal polyuria
O. Natsume (2007)
10.1016/S0090-4295(00)00603-8
Cross-sectional study of nocturia in both sexes: analysis of a voluntary health screening project.
G. Schatzl (2000)
10.1016/S0302-2838(03)00141-6
Snoring as a cause of nocturia in men with lower urinary tract symptoms.
A. Kinn (2003)
10.4172/2157-7536.1000130
Hormones and Nocturia: Guidelines for Medical Treatment?
An-sofie Goessaert (2013)
bple: Pathophysiology and Clinical Implications
M. Miller (2011)
10.1016/j.urology.2014.05.040
Change of nocturnal polyuria after holmium laser enucleation of the prostate in patients with benign prostatic hyperplasia.
W. Choi (2014)
10.1046/j.1464-410X.90.s3.5.x
What is nocturnal polyuria?
Å. Rembratt (2002)
10.3109/0886022X.2015.1088335
Central hemodynamics, vascular stiffness, and nocturia in patients with type 2 diabetes
B. Afsar (2015)
10.1007/978-3-7091-0631-0_8
The impact of changes in fluid regulation hormones during aging
J. C. Djurhuus (2004)
10.1111/ijcp.12786
Comparison of nocturia response to desmopressin treatment in elderly men with and without nocturnal polyuria in real‐life practice
S. Chen (2016)
10.1016/S0140-6736(00)82039-5
Relation of nocturnal polyuria of the elderly to essential hypertension
P. McKeigue (2000)
10.1002/NAU.20492
Biochemical and body composition analysis of nocturia in the elderly
K. Sugaya (2008)
10.1111/j.1532-5415.2000.tb02608.x
Nocturnal Polyuria in Older People: Pathophysiology and Clinical Implications
M. Miller (2000)
10.1002/14651858.CD004463.PUB2
Drugs for nocturia in adults
A. Cannon (2016)
10.1016/S0090-4295(02)01818-6
Relation between nocturnal voiding frequency and nocturnal urine production in older men:a population-based study.
M. Blanker (2002)
10.1016/S0090-4295(01)01645-4
Efficacy of desmopressin in treatment of refractory nocturia in patients older than 65 years.
H. C. Kuo (2002)
Prevalence of nocturnal polyuria in patients with benign prostatic hyperplasia.
H. F. Yoong (2005)
Semantic Scholar Logo Some data provided by SemanticScholar