Please confirm you are human (Sign Up for free to never see this)
← Back to Search
Protein Interactions With Oligo(ethylene Glycol) (OEG) Self-assembled Monolayers: OEG Stability, Surface Packing Density And Protein Adsorption
L. Li, S. Chen, S. Jiang
Published 2007 · Materials Science, Medicine
Save to my Library
Download PDFAnalyze on Scholarcy
We present a study of protein adsorption on oligo(ethylene glycol) (OEG) self-assembled monolayers (SAMs) at a range of OEG surface densities. OEG SAMs were formed in mixed ethanol and water solutions at different assembly temperatures to adjust the packing density of EG4-SAMs. These SAMs were characterized using X-ray photoelectron spectroscopy (XPS). Fibrinogen adsorption on these surfaces was measured by a surface plasmon resonance (SPR) sensor at different temperatures. This work is aimed at addressing three important issues for protein–OEG interactions, i.e., (i) OEG stability, (ii) the correlation between OEG surface densities and surface non-fouling properties, and (iii) protein adsorption on OEG surfaces at different temperatures.
This paper references
Koleske, Poly(ethylene Oxide)
J.Y.F.E. Bailey (1984)
Superlow fouling sulfobetaine and carboxybetaine polymers on glass slides.
Z. Zhang (2006)
Inhibition of monocyte adhesion and fibrinogen adsorption on glow discharge plasma deposited tetraethylene glycol dimethyl ether
M. Shen (2001)
Dual-functional biomimetic materials: nonfouling poly(carboxybetaine) with active functional groups for protein immobilization.
Z. Zhang (2006)
A. J. Pertsin
Controlled Chemical and Structural Properties of Mixed Self-assembled Monolayers of Alkanethiols on Au (111)
S. Chen (2000)
Computer Simulation of Water near the Surface of Oligo(ethylene glycol)-Terminated Alkanethiol Self-Assembled Monolayers†
Alexander J. Pertsin and (2000)
Poly(Ethylene Glycol) Chemistry
J. M. Harris (1992)
Molecular simulation study of water interactions with oligo (ethylene glycol)-terminated alkanethiol self-assembled monolayers.
J. Zheng (2004)
Molecular Conformation in Oligo(ethylene glycol)-Terminated Self-Assembled Monolayers on Gold and Silver Surfaces Determines Their Ability To Resist Protein Adsorption
P. Harder (1998)
Control of protein adsorption: molecular level structural and spatial variables.
D. Vanderah (2004)
SOLVENT EFFECT ON THE STRUCTURE OF THE SELF-ASSEMBLED MONOLAYER OF ALKANETHIOL
R. Yamada (1999)
Self-Assembled Monolayers of Methyl 1-Thiahexa(ethylene oxide) for the Inhibition of Protein Adsorption
D. Vanderah (2002)
Protein adsorption on oligo(ethylene glycol)-terminated alkanethiolate self-assembled monolayers: The molecular basis for nonfouling behavior.
L. Li (2005)
Grafted poly(ethylene oxide) brushes as nonfouling surface coatings.
D. Leckband (1999)
Surface grafted sulfobetaine polymers via atom transfer radical polymerization as superlow fouling coatings.
Z. Zhang (2006)
D. J. Vanderah
K. L. Prime
Poly(Ethylene Glycol) Chemistry Biotechnical and Biomedical Applications
J. M. Harris (1992)
A Survey of Structure−Property Relationships of Surfaces that Resist the Adsorption of Protein
E. Ostuni (2001)
Molecular-Scale Mixed Alkanethiol Monolayers of Different Terminal Groups on Au(111) by Low-Current Scanning Tunneling Microscopy
Lingyan Li (2003)
Oxidation of polyethylene glycols by alcohol dehydrogenase.
D. Herold (1989)
Effect of Temperature on Structure of the Self-Assembled Monolayer of Decanethiol on Au(111) Surface
R. Yamada (2000)
Spectral surface plasmon resonance biosensor for detection of staphylococcal enterotoxin B in milk.
J. Homola (2002)
Grand Canonical Monte Carlo Simulations of the Hydration Interaction between Oligo(ethylene glycol)-Terminated Alkanethiol Self-Assembled Monolayers
A. Pertsin (2002)
F. Bailey (1976)
Adsorption of proteins onto surfaces containing end-attached oligo(ethylene oxide): a model system using self-assembled monolayers
K. Prime (1993)
Probing resistance to protein adsorption of oligo(ethylene glycol)-terminated self-assembled monolayers by scanning force microscopy
K. Feldman (1999)
Biomaterials Science: An Introduction to Materials in Medicine
B. Ratner (1996)
This paper is referenced by
Modulation of barnacle (Balanus amphitrite Darwin) cyprid settlement behavior by sulfobetaine and carboxybetaine methacrylate polymer coatings
N. Aldred (2010)
Polymer brushes showing non-fouling in blood plasma challenge the currently accepted design of protein resistant surfaces.
C. Rodriguez-Emmenegger (2011)
Polyampholyte polymers as a versatile zwitterionic biomaterial platform
Matthew T. Bernards (2014)
Non-labelled surface sensitive techniques as platforms for pharmaceutical nanotechnology research
Huamin Liang (2013)
Nanoparticles for drug delivery prepared from amphiphilic PLGA zwitterionic block copolymers with sharp contrast in polarity between two blocks.
Z. Cao (2010)
Surface plasmon resonance biosensor with high anti-fouling ability for the detection of cardiac marker troponin T.
J. Liu (2011)
3D-printable zwitterionic nano-composite hydrogel system for biomedical applications
Nathalie Sällström (2020)
High-content imaging with micropatterned multiwell plates reveals influence of cell geometry and cytoskeleton on chromatin dynamics.
T. Harkness (2015)
Adsorption of Oligonucleotides on Quantum Dots Coated with Zwitterionic Ligands and Other Water-Soluble Ligands
Tasmea Mahmud (2012)
Surface Structures of Amine-Bearing Siloxane Self-Assembled Monolayers: Influence of Conformation on Methylene Vibrational Frequencies
Matthew D King (2014)
Functionalizable and nonfouling zwitterionic carboxybetaine hydrogels with a carboxybetaine dimethacrylate crosslinker.
Louisa R. Carr (2011)
Molecular dynamics simulations suggest conformational and hydration difference between zwitterionic poly (carboxybetaine methacrylate) and poly (ethylene glycol)
Hao-miao Zhu (2020)
Cross-linked carboxybetaine SAMs enable nanoparticles with remarkable stability in complex media.
W. Yang (2014)
Surface Hydration: Principles and Applications Toward Low-fouling/nonfouling Biomaterials
Shenfu Chen (2010)
Highly stable, protein resistant thin films on SiC-modified silicon substrates.
G. Qin (2010)
Nonfouling polyampholyte polymer brushes with protein conjugation capacity.
Tapashree Tah (2012)
Surface tailoring of nanoparticles via mixed-charge monolayers and their biomedical applications.
X. Liu (2014)
Protein-resistant hyperbranched polyethyleneimine brush surfaces.
S. Suriyanarayanan (2013)
Nanoscale engineering of low-fouling surfaces through polydopamine immobilisation of zwitterionic peptides.
J. Cui (2014)
Zwitterionic-Modified Starch-Based Stealth Micelles for Prolonging Circulation Time and Reducing Macrophage Response.
L. Ye (2016)
Zwitterionic supramolecular nanoparticles: self-assembly and responsive properties.
Carmen Stoffelen (2015)
Polymer Brushes and Microorganisms
M. Ramstedt (2017)
Zwitterionic poly(carboxybetaine) hydrogels for glucose biosensors in complex media.
W. Yang (2011)
Preparation of Biomimetic Zwitterionic Core Cross-Linked Nanocarriers for Control Release of Bioactive Agents
X. Wang (2013)
Synthesis of non-fouling poly[ N -(2-hydroxypropyl)methacrylamide] brushes by photoinduced SET-LRP
M. Vorobii (2015)
Superhydrophilicity and strong salt-affinity: Zwitterionic polymer grafted surfaces with significant potentials particularly in biological systems.
D. Li (2020)
Synthesis and characterization of zwitterionic peptides derived from natural amino acids and their resistance to protein adsorption
Caicai Lu (2014)
Dual-Functional Zwitterionic Carboxybetaine for Highly Sensitive and Specific Cancer Biomarker Detection in Complex Media Using SPR Biosensors
Norman D. Brault (2012)
The effect of lightly crosslinked poly(carboxybetaine) hydrogel coating on the performance of sensors in whole blood.
W. Yang (2012)
Ultra-low fouling and high antibody loading zwitterionic hydrogel coatings for sensing and detection in complex media.
Ying-Nien Chou (2016)
Optimization of DNA-directed immobilization on mixed oligo(ethylene glycol) monolayers for immunodetection.
W. Hu (2012)
Combining Surface Analytical and Computational Techniques to Investigate Orientation Effects of Immobilized Proteins
Elisa T Harrison (2017)See more