Online citations, reference lists, and bibliographies.
← Back to Search

Clinical Manifestations Of Cerebrovascular Hypoplasias In Childhood

V. Bojinova, P. Dimova, L. Belopitova
Published 2000 · Medicine

Cite This
Download PDF
Analyze on Scholarcy
The aim of the study was to analyze cerebrovascular hypoplasia in childhood and its clinical manifestations in a clinical population of 205 children aged 3 to 14 years. Cerebrovascular hypoplasias were diagnosed using angiography (n=63), magnetic resonance angiography, and transcranial Doppler ultrasonography. Hypoplasias were localized in the internal carotid artery in 41.9% of patients, in the middle cerebral artery in 54.1%, the anterior cerebral artery in 1.0%, and in the vertebro-basilar system in 3.0%. Clinical manifestations included transient ischemic attacks (21% of patients), cerebral infarcts (17%), progressive unilateral cerebral hemisphere atrophy (1.0%), focal and secondary generalized epileptic seizures (56.1%), and migraine-like headache (4.9%). Hypoplasias of the internal carotid artery and middle cerebral artery manifested as focal and secondary generalized epileptic seizures, transient ischemic attacks, cerebral infarcts, migraine-like headache, and progressive unilateral cerebral hemisphere atrophy, in descending order of frequency. Hypoplasias in the anterior cerebral artery or the basilar artery caused cerebral infarcts, and hypoplasias in the vertebral arteries caused transient ischemic attacks. This article discusses the pathophysiology of ischemia in the territory of the hypoplastic cerebral artery in childhood, as well as possibilities for noninvasive neuroimaging for diagnosis of cerebrovascular hypoplasias. (J Child Neurol 2000;15:166-171).
This paper references
Transcranial Doppler ultrasound for the assessment of intracranial arterial flow velocity--Part 2. Evaluation of intracranial arterial disease.
M. Hennerici (1987)
Presentation, clinical course, and outcome of childhood stroke.
M. J. Lanska (1991)
Epidemiological Investigation of Cerebrovascular Disease in Iceland, 1958–1968 (Ages 0‐35 years)
G. Gudmundsson (1977)
On the topic of the cerebrovascular malformations in the vertebro-basilar system in childhood
V Bojinova (1993)
Cerebrovascular disease, in Swaiman KI (ed): Pediatric Neurology
GS Golden (1989)
Basal ganglia and thalamic infarction in children. Cause and clinical features.
M. C. Brower (1996)
Ueber die klinische Vielgestaltigkeit der zerebralen Gefaesserkrankungen im Kindesalter
I Georgiev (1990)
Headache in Acute Cerebrovascular Disease: A Prospective Clinical Study in 240 Patients
A. Arboix (1994)
Transcranial color duplex sonography of basal cerebral arteries: reference data of flow velocities from childhood to adulthood.
M. Schöning (1996)
Neurological manifestations associated with internal carotid loops and kinks in children.
N. Sarkari (1970)
Ischemia in the territory of a hypoplasic vertebro-basilar system
S Chaturvedi (1999)
Delayed parkinsonism Associated with Hypotension in a Child Undergoing Open‐heart Surgery
R. Straussberg (1993)
The significance of elongation and angulation of the carotid artery: a negative view.
Garland D. Perdue (1975)
Diagnostic and therapeutic problems in cerebrovascular determined epilepsies in childhood, abstract
V Bojinova (1997)
Diagnostic and therapeutic problems in cerebrovascular determined epilepsies in childhood, abstract
V Bojinova (1997)
Angiography and the evaluation of cerebrovascular disease in childhood.
P. Burrows (1996)
Transcranial Doppler sonography in childhood, in Shotekov P (ed): Ultrasound Diagnosis in the Vessels of the Brain and Legs
V Bojinova (1998)
O. Eeg-Olofsson (1983)
[Transcranial Doppler sonography in childhood. 1. Study technic and biological effect magnitudes].
H. Bode (1989)
Double pathology in Rasmussen's syndrome
Y. Hart (1998)
Age dependence of flow velocities in basal cerebral arteries.
H. Bode (1988)
Bilateral infarction in the territory of the anterior cerebral arteries.
A. Minagar (1999)
Ischemia in the territory of a hypoplastic vertebrobasilar system
S. Chaturvedi (1999)
Epilepsie chez des enfants avec anomalies congenitales des carotides, abstract
I Georgieff (1976)
Disorders of the Cerebral Circulation in Children
A Ratner (1983)
Transcranial Doppler sonographic studies in acute ischemic disturbances of the cerebral circulation in childhood
V Bojinova (1993)
Cerebrovascular disease in infants and children
B. Schoenberg (1978)
Congenital absence and aberrant course of the internal carotid artery
S. Takahashi (2004)

This paper is referenced by
Headache in children.
V. Guidetti (2010)
Transcranial Doppler sonography in children: review of a seven-year experience.
W. Hirsch (2002)
A new model of stroke and ischemic seizures in the immature mouse.
A. Comi (2004)
Does lenticulostriate vasculopathy predipose to ischemic brain infarct? A case report
I. Ivanov (2012)
Diagnostic Imaging of Carotid Artery
L. Manchev (2018)
Sonographic Diagnosis of Congenital Variations of the Extracranial Vertebral Artery and Assessment of Its Circulation
Y. Wang (2009)
Is Vertebral Artery Hypoplasia a Predisposing Factor for Posterior Circulation Cerebral Ischemic Events? A Comprehensive Review
A. Katsanos (2013)
Recent development in paediatric headache
V. Guidetti (2001)
Application of transcranial Doppler ultrasound in pediatric patients: how to verify the indications?
I. Kopyta (2010)
A review of long-term EEG monitoring in critically ill children with hypoxic-ischemic encephalopathy, congenital heart disease, ECMO, and stroke.
N. Abend (2013)
Transcranial Doppler Sonography in Pediatric Neurocritical Care
Kerri L. LaRovere (2015)
Internal Carotid Artery Hypoplasia
Pei-Ya Chen (2015)
[Pathological deformation of the carotid arteries].
D. Zerbino (2015)
Semantic Scholar Logo Some data provided by SemanticScholar