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An Experimental Investigation Of The Fabrication Of Biodegradable Zinc–hydroxyapatite Composite Material Using Microwave Sintering

D. Pathak, P. M. Pandey
Published 2020 · Materials Science

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The present work focuses on the fabrication of zinc–hydroxyapatite biodegradable composite with the use of pressureless microwave sintering for the orthopedic load-bearing application. The samples were prepared using the powder metallurgy process. The powders of both materials were homogeneously mixed in the quantified proportions to form the uniform mixture. For the fabrication of samples, the planning of experiments was done with the central composite design. The effect of process factors such as the weight percentage of hydroxyapatite, compaction pressure, and microwave sintering factors such as sintering temperature, heating rate, and soaking time on the compressive yield strength and sintered density was evaluated. Cylindrical samples were prepared for compression testing. The experimental results exhibited the increase in the compressive yield strength as well as the sintered density with the decrease in the hydroxyapatite percentage and an increase in the compaction pressure. The results also revealed that the compressive yield strength and sintered density were found to be increased as the heating rate and sintering temperature increased. Sample characterization was carried out for phase determination and composition of the elements. The optimum process factors were obtained after the regression analysis, and the results of the optimum process factors were also verified with the confirmation experiments. The in vitro corrosion testing of the sample prepared with optimum factors was also carried out in the simulated body fluid at a temperature of 37 ± 0.5 ℃. The fabricated sample showed a good agreement between the mechanical and degradation properties as required for a human bone.
This paper references
10.1080/07853890701689645
Calcium and phosphate homeostasis: Concerted interplay of new regulators
Kirsten Y. Renkema (2008)
10.1098/rsif.2008.0419.focus
Bioactive ceramic-based materials with designed reactivity for bone tissue regeneration
C. Ohtsuki (2009)
10.1016/S0921-5093(00)01942-0
Production of aluminium matrix composite components using conventional PM technology
G. O'Donnell (2001)
10.1016/0267-6605(87)90044-8
Bioceramics for hard tissue replacements
H. Kawahara (1987)
Bioceramics for hard tissue replacement
H. Kawahara (1987)
10.1016/J.JALLCOM.2007.11.047
Effect of heating rate during hybrid microwave sintering on the tensile properties of magnesium and Mg/Y2O3 nanocomposite
K. S. Tun (2008)
10.1038/srep10719
Development of biodegradable Zn-1X binary alloys with nutrient alloying elements Mg, Ca and Sr
H. F. Li (2015)
10.1007/S11661-007-9153-2
The Effect of Particle Shape on the Sintering of Aluminum
Z. Liu (2007)
10.4172/2155-952X.1000178
Magnesium, Iron and Zinc Alloys, the Trifecta of Bioresorbable Orthopaedic and Vascular Implantation - A Review
Michael Heiden (2015)
10.1080/10426914.2012.709349
Effects of Heating Rate and Sintering Temperature on 316 L Stainless Steel Powders Sintered Under Multiphysical Field Coupling
Ankang Du (2012)
10.1361/105994903770343187
Equation for the density of particle-reinforced metal matrix composites: A new approach
S. C. Sharma (2003)
10.4028/www.scientific.net/KEM.751.37
Effect of Compaction Pressure and Sintering Time on the Properties of Sintered Cu-10Sn Bronze
Narut Nakrod (2017)
10.1016/j.msec.2016.11.138
Fabrication of biodegradable Zn-Al-Mg alloy: Mechanical properties, corrosion behavior, cytotoxicity and antibacterial activities.
Hamid Reza Bakhsheshi-Rad (2017)
10.1016/j.actbio.2018.03.007
In vitro and in vivo studies on zinc-hydroxyapatite composites as novel biodegradable metal matrix composite for orthopedic applications.
H. Yang (2018)
10.1016/J.MSEA.2003.08.004
Optimisation of compaction and liquid-state sintering in sintering and dissolution process for manufacturing Al foams
Y. Zhao (2004)
10.1016/J.BIOMATERIALS.2006.01.017
How useful is SBF in predicting in vivo bone bioactivity?
T. Kokubo (2006)
10.1016/j.actbio.2018.10.015
Microstructure, mechanical properties, biocompatibility, and in vitro corrosion and degradation behavior of a new Zn-5Ge alloy for biodegradable implant materials.
Xian Tong (2018)
10.1007/s10856-015-5403-9
A unified in vitro evaluation for apatite-forming ability of bioactive glasses and their variants
A. L. B. Maçon (2015)
10.1016/J.JMST.2013.03.002
Biodegradable Materials for Bone Repairs: A Review
L. Tan (2013)
10.1016/j.msec.2012.11.002
On the cytocompatibility of biodegradable Fe-based alloys.
Michael Schinhammer (2013)
10.1016/J.BIOMATERIALS.2006.12.027
Biodegradable magnesium-hydroxyapatite metal matrix composites.
F. Witte (2007)
10.1016/J.JMA.2018.02.003
Review of magnesium-based biomaterials and their applications
Nurettin Sezer (2018)
10.1007/s10856-015-5473-8
Iron and iron-based alloys for temporary cardiovascular applications
A. Francis (2015)
10.1002/(SICI)1097-4636(19970915)36:4<454::AID-JBM3>3.0.CO;2-D
Mechanical and morphologic investigation of the tensile strength of a bone-hydroxyapatite interface.
J. Edwards (1997)
Effect of compaction pressure and sintering time on Pathak and Pandey 2879 the properties of sintered Cu-10Sn bronze
N Nakrod (2017)
10.1007/978-1-84628-366-6_4
Biodegradable Orthopedic Implants
H. Park (2007)
10.1016/J.MATLET.2015.07.151
Microstructure, mechanical properties, in vitro degradation behavior and hemocompatibility of novel Zn-Mg-Sr alloys as biodegradable metals
Xi-wei Liu (2016)
Review of magnesiumbased biomaterials and their applications
N Sezer (2018)
10.1016/j.actbio.2014.07.005
Recent advances on the development of magnesium alloys for biodegradable implants.
Yongjun Chen (2014)
10.3390/books978-3-03897-387-4
Biodegradable metals
Y. Zheng (2014)
10.1371/journal.pone.0206247
Effect of sintering parameters on physical and mechanical properties of powder injection moulded stainless steel-hydroxyapatite composite
M. I. Ramli (2018)
10.1177/0954406218778304
Rapid manufacturing of biodegradable pure iron scaffold using amalgamation of three-dimensional printing and pressureless microwave sintering
Pawan Sharma (2019)
10.1002/adma.201300226
Zinc exhibits ideal physiological corrosion behavior for bioabsorbable stents.
Patrick K. Bowen (2013)
Physico-chemical properties and microstructure of hydroxyapatite-316L stainless steel biomaterials
邹俭鹏 (2004)
10.1016/j.ultras.2018.07.004
Machining forces in ultrasonic‐vibration assisted end milling
G. Verma (2019)
Standard test methods for density of compacted or sintered powder metallurgy (PM) products using Archimedes
B ASTM (2019)
10.1016/S1006-7191(08)60054-X
Review on Research and Development of Magnesium Alloys
Z. Yang (2008)
10.1016/S1003-6326(06)60297-5
Review of studies on corrosion of magnesium alloys
R. Zeng (2006)
Sintering: Densification, Grain Growth and Microstructure
S. L. Kang (2005)
Standard practice for calculation of corrosion rates and related information
E Measurements (1999)
10.1007/s10853-014-8066-x
Microstructure, corrosion, and mechanical properties of compression-molded zinc-nanodiamond composites
Miao Yu (2014)
10.1016/j.actbio.2011.05.008
Mechanical and corrosion properties of newly developed biodegradable Zn-based alloys for bone fixation.
D. Vojtěch (2011)
10.1016/j.actbio.2009.07.039
Design strategy for biodegradable Fe-based alloys for medical applications.
Michael Schinhammer (2010)
10.1016/j.msec.2019.01.114
Corrosion behaviour of the porous iron scaffold in simulated body fluid for biodegradable implant application.
Pawan Sharma (2019)
International Standard Mechanical testing of metals – ductility testing – compression test for porous and cellular metals
I. Standard (2011)
10.1016/J.PNSC.2014.08.014
Progress of biodegradable metals
H. F. Li (2014)
10.1016/J.MATCHEMPHYS.2011.07.008
Effect of microwave and conventional heating on sintering behavior and properties of Al-Mg-Si-Cu alloy
C. Padmavathi (2011)
Standard test methods for density of compacted or sintered powder metallurgy (PM) products using Archimedes' principle
Astm B962 (2019)
10.1088/1757-899X/377/1/012209
Effect of compaction pressure on microstructure, density and hardness of Copper prepared by Powder Metallurgy route
Manish Dixit (2018)
10.1557/OPL.2012.671
Potential Bone Replacement Materials Prepared by Two Methods
S. Lee (2012)
10.1007/S11661-999-0335-Y
Surface oxide and the role of magnesium during the sintering of aluminum
R. Lumley (1999)
10.1002/3527606181.CH44
Effect of Compaction Pressure and Powder Grade on the Microstructure, Hardness and Surface Topography of Steam Oxidized Sintered Iron
J. D. Mello (2006)
10.1016/j.bone.2015.11.018
Mechanical properties of cortical bone and their relationships with age, gender, composition and microindentation properties in the elderly.
M. J. Mirzaali (2016)



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