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Usefulness Of Vortioxetine Noted In Depression Secondary To Hypoxic Brain Injury And Residual Cognitive Deficits

Syeda Maheen Ahsan, Syed Daniyal Ahsan, Osman Khalid, Hina Agha

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We report on our experience of treating depression secondary to hypoxic brain injury with the antidepressant vortioxetine to share in the growing body of evidence. Our patient was referred to a community mental health team with depression, amotivation and memory difficulties following a myocardial infarction and cardiac arrest 2 years prior. Regardless of motor recovery, major cognitive deficits remained; however, neurorehabilitation was impossible due to severe depression. We tried vortioxetine in the light of two failed antidepressants and saw a remarkable improvement in mood, motivation and engagement.