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Biochemisch-pharmakologische Untersuchung Pflanzlicher Arzneistoffe. II . Hemmung Der Acetylcholinesterase Durch Monoterpenderivate In Vitro / Molecular Pharmacological Investigation Of Medicinal Plant Substances. II. Inhibition Of Acetylcholinesterase By Monoterpene Derivatives In Vitro

L. Gracza

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Abstract Monoterpene derivatives with spasmolytic activity inhibited acetylcholinesterase (ACHE, EC 3.1.1.7) in a dose dependent manner in vitro. The median inhibitory concentrations ranges between 10-4 ᴍ and 10-2 ᴍ. A significance of our finding may by the possible explanation of effects of monoterpene derivatives seen in distony of digestive tract.