Online citations, reference lists, and bibliographies.
← Back to Search

Comparison Between Simultaneously Recorded Amplitude Integrated Electroencephalogram (cerebral Function Monitor) And Standard Electroencephalogram In Neonates.

M. Toet, W. van der Meij, L. D. de Vries, C. Uiterwaal, Kees C van Huffelen
Published 2002 · Medicine

Cite This
Download PDF
Analyze on Scholarcy
Share
OBJECTIVE To assess the value and the limitations of amplitude integrated electroencephalogram (EEG) using the cerebral function monitor (CFM) in comparison with standard EEG in neonates who have hypoxic ischemic encephalopathy or were suspected of having convulsions. METHODS In 36 neonates with a gestational age > or =36 weeks, CFM and simultaneously recorded EEG traces were analyzed off-line and independently classified. CFM background activity: continuous normal voltage; continuous normal voltage, slightly discontinuous (DNV); burst-suppression (BS); continuous extremely low voltage; flat tracing. CFM epileptiform activity: suspected epileptic activity, single seizure (SS), repetitive seizures (RS), status epilepticus (SE). EEG background activity: normal, depressed, low voltage undifferentiated, excessive discontinuity, BS, no activity. Epileptiform activity: interictal unifocal, interictal multifocal, ictal unifocal, ictal multifocal, SE. RESULTS A total of 33 traces were suitable for analysis. Interobserver agreement on background activity was reached in 31 cases (kappa = 0.92) for CFM and in 27 cases (kappa = 0.74) for EEG. There was full agreement on CFM ictal activity (RS, SS, or SE) and EEG ictal activity. A normal CFM (continuous normal voltage) corresponded with a normal or a depressed EEG in 90% of the cases. The positive predictive value for a severely abnormal CFM (BS, continuous extremely low voltage, flat tracing) to correspond with a severely abnormal EEG (excessive discontinuity, BS, low voltage undifferentiated, no activity) was 100% (negative predictive value, 80%; sensitivity, 76%; specificity, 100%). DNV (10) on CFM corresponded either with depressed (6) or excessive discontinuity (4) on EEG. Ictal activity on EEG corresponded with SS, RS, or SE on CFM in 8 cases (sensitivity, 80%; specificity, 100%; positive predictive value, 100%; negative predictive value, 92%). CONCLUSION CFM is a reliable tool for monitoring both background patterns (especially normal and severely abnormal) and ictal activity. Certain focal, low amplitude, and very short periods of seizure discharges can be missed. We recommend using CFM as a monitoring device and performing intermittent standard EEG whenever there is any doubt about the classification of the CFM (ie, DNV pattern or suspected epileptiform activity).



This paper is referenced by
10.1016/J.CLP.2006.06.002
Amplitude integrated electroencephalography in the full-term newborn.
L. D. de Vries (2006)
10.1097/WNP.0b013e3181a18711
Engineering Aspects of the Quantified Amplitude-Integrated Electroencephalogram in Neonatal Cerebral Monitoring
M. Quigg (2009)
10.1016/B978-1-4377-3611-3.00015-8
Chapter 15 – Amplitude-Integrated EEG and Its Potential Role in Augmenting Management Within the NICU
Mona C. Toet (2012)
10.4018/978-1-4666-0975-4.CH011
Automated Neonatal Brain Monitoring
Maarten De Vos (2012)
10.1016/S0095-5108(03)00029-0
Follow-up data their use in evidence-based decision-making.
T. O'Shea (2003)
10.1097/PCC.0000000000000352
Detection of Electrographic Seizures by Critical Care Providers Using Color Density Spectral Array After Cardiac Arrest Is Feasible*
A. Topjian (2015)
10.1111/j.1651-2227.2007.00223.x
An algorithm for the automatic detection of seizures in neonatal amplitude‐integrated EEG
C. M. L. Lommen (2007)
10.1016/J.PEDIATRNEUROL.2005.06.018
Amplitude-integrated electroencephalography: a tool for monitoring silent seizures in neonates.
E. Shany (2006)
10.1159/000097456
The Added Value of Simultaneous EEG and Amplitude-Integrated EEG Recordings in Three Newborn Infants
N. D. de Vries (2006)
10.1053/J.NAINR.2011.07.005
Amplitude-integrated Electroencephalography: A New Approach to Enhancing Neurologic Nursing Care in the Neonatal Intensive Care Unit☆
Shuyuann Wang Foreman (2011)
10.1109/ICSIPA.2015.7412252
Amplitude-integrated EEG processing and its performance for automatic seizure detection
Chavin Satirasethawong (2015)
10.1542/peds.2006-3007
Neurodevelopmental Outcome in Term Infants With Status Epilepticus Detected With Amplitude-Integrated Electroencephalography
L. V. van Rooij (2007)
10.14238/PI47.2.2007.47-54
An overview of an amplitude integrated EEG
S. Handryastuti (2007)
10.1016/j.jpeds.2008.03.004
Assessment of neonatal electroencephalography (EEG) background by conventional and two amplitude-integrated EEG classification systems.
R. Shellhaas (2008)
The Clinical Value of Intensive Monitoring in Term Asphyxiated Newborns
Renate Swarte (2010)
10.5167/uzh-108335
The amplitude-integrated EEG (aEEG)in the early prediction of outcome in the very preterm newborn
G. Natalucci (2014)
10.3233/THC-2003-11602
Sensors in neonatal monitoring: current practice and future trends.
Ivana Murković (2003)
10.1371/journal.pone.0165744
Amplitude Integrated Electroencephalogram as a Prognostic Tool in Neonates with Hypoxic-Ischemic Encephalopathy: A Systematic Review
R. Del Río (2016)
10.1891/0730-0832.27.5.329
Cerebral Monitoring of the Term Infant
Shelly V Lavery (2008)
10.1016/J.SINY.2006.07.011
Continuous brain-function monitoring: state of the art in clinical practice.
L. Hellström‐Westas (2006)
10.1007/978-1-60327-532-3_2
Diagnosing and Monitoring Seizures in the ICU: The Role of Continuous EEG for Detection and Management of Seizures in Critically Ill Patients
D. Friedman (2010)
10.1007/978-3-319-49557-6_3
Diagnosing and Monitoring Seizures in the ICU: The Role of Continuous EEG for Detection and Management of Seizures in Critically Ill Patients, Including the Ictal-Interictal Continuum
G. Osman (2017)
10.1016/j.braindev.2018.04.010
Relationship between prolonged neural suppression and cerebral hemodynamic dysfunction during hypothermia in asphyxiated piglets
Wataru Jinnai (2018)
10.1186/s40348-015-0016-4
Propofol administration to the maternal-fetal unit improved fetal EEG and influenced cerebral apoptotic pathway in preterm lambs suffering from severe asphyxia
M. Seehase (2015)
10.1186/1471-2431-8-17
The TOBY Study. Whole body hypothermia for the treatment of perinatal asphyxial encephalopathy: A randomised controlled trial
D. Azzopardi (2008)
MDER_A_214662 489..496
Maliheh Kadivar (2019)
10.2741/E78
S100B protein and near infrared spectroscopy in preterm and term newborns.
L. G. Tina (2010)
10.1038/sj.jp.7211291
Amplitude-Integrated EEG in Preterm Infants: Maturation of Background Pattern and Amplitude Voltage with Postmenstrual Age and Gestational Age
J. Sisman (2005)
10.1080/1086508X.2011.11079816
EEG Monitoring during Therapeutic Hypothermia in Neonates, Children, and Adults
N. Abend (2011)
10.1515/jpm-2011-0292
Therapeutic hypothermia and hypoxic ischemic encephalopathy: opinion and practice of pediatricians in South Africa
Y. Joolay (2012)
10.3389/fped.2020.00239
Management of Multi Organ Dysfunction in Neonatal Encephalopathy
M. O'Dea (2020)
10.1016/J.EARLHUMDEV.2006.05.004
Lack of influence of mild hypothermia on amplitude integrated-electroencephalography in neonates receiving extracorporeal membrane oxygenation.
M. Horan (2007)
See more
Semantic Scholar Logo Some data provided by SemanticScholar