Online citations, reference lists, and bibliographies.
← Back to Search

Effect Of Vitamin E On Carbonic Anhydrase Enzyme Activity In Rainbow Trout (Oncorhynchus Mykiss) Erythrocytes In Vitro And In Vivo

Ş. Aras-Hisar, O. Hisar, Ş. Beydemir, I. Gülçin, T. Yanik

Save to my Library
Download PDF
Analyze on Scholarcy Visualize in Litmaps
Share
Reduce the time it takes to create your bibliography by a factor of 10 by using the world’s favourite reference manager
Time to take this seriously.
Get Citationsy
Considering that the excessive usage of vitamin E causes hypervitaminosis and thus reduces blood erythrocyte concentrations, therefore it is worth studying how its pharmacological dosage affects the activity of carbonic anhydrase (CA) enzyme found in erythrocytes of rainbow trout (Oncorhynchus mykiss)in vitroandin vivo. Vitamin E inhibited CA enzyme and the IC50value of the vitamin was 0.039 mMin vitro. Similarly, it was seen that vitamin E inhibited CA enzyme activity after the first hour following vitamin E injectionsin vivo. The activities of CA in groups of trout given vitamin E injection were measured at 1, 3 and 5 h and the corresponding activities were found to be 772.7 ± 290.5 (P < 0.05), 1286.4 ± 378.2 and 1005.7 ± 436.1 enzyme units (EU) g Hb-1. The difference over the control was significant (P < 0.05) in the first hour and insignificant at 3 and 5 h (P ? 0.05). The activity of CA in the control, which did not contain vitamin E, was determined as 1597.7 ± 429.0 EU g Hb-1.