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Interaction Study Of Moxifloxacin With Cu(II) Ion Using Square-wave Voltammetry And Its Application In The Determination In Tablets

M. A. G. Trindade, P. A. C. Cunha, T. A. de Araújo, G. M. da Silva, V. S. Ferreira

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This work presents an electroanalytical method for the determination of moxifloxacin (MOXI) in tablets by its interaction with Cu(II) ion and subsequent electrochemical reduction at hanging mercury drop electrode (HMDE). A well-defined reduction peak at -0.21 V vs. Ag/AgCl in Phosphate buffer 0.04 mol L-1 pH 8.0 was observed for the complex reduction MOXI-Cu(II), using square-wave voltammetry (SWV). Using a 10 s of accumulation time at -0.40 V was found a limit detection of 3.60x10-8 mol l-1. The obtained results have shown good agreement with those obtained by spectrophotometric method.