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Does The Breast Cancer Age At Diagnosis Differ By Ethnicity? A Study On Immigrants To Sweden.
K. Hemminki, Seyed Mohsen Mousavi, J. Sundquist, A. Brandt
Published 2011 · Medicine
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BACKGROUND Age-specific incidence rates for breast cancer in low-risk and high-risk ethnic populations differ by age at which the incidence maximum is reached: around 50 years in low-risk populations and over 60 years in high-risk populations. The interpretation of these differences remains unsettled, one line primarily referring to biological differences, the second one to cohort effects of rapidly increasing rates in young populations, and the third one to incomplete registration of cancer in the elderly. METHODS The nationwide Family-Cancer Database was used to analyze standardized incidence ratios (SIRs) and age at diagnosis of breast cancer in female immigrants to Sweden by their region of origin compared with women native to Sweden matched on birth year and other relevant factors. RESULTS We showed first that the SIRs for breast cancer were lower in many immigrant groups compared with natives of Sweden; women from Turkey had the lowest SIR of 0.45, followed by those from Chile (0.54) and Southeast Asia (0.57). Women from nine regions showed an earlier mean age at diagnosis than their matched Swedish controls, the largest differences being 5.5 years for women from Turkey, 5.1 years for those from Asian Arab and "Other African" countries, 4.3 years for those from Iran, and 4.0 years for those from Iraq. CONCLUSIONS The results show that in many immigrant groups, the diagnostic age is earlier (<50 years) than in natives of Sweden (>50 years), suggesting that true biological factors underlie the differences. These factors may explain much of the international variation in breast cancer incidence. Identifying these factors should advance understanding of breast cancer etiology and prevention.
This paper references
Age Distribution of Breast Cancer in the Middle East, Implications for Screening
Seyed Mohsen Mousavi (2009)
Mammographic screening is dramatically changing age-incidence data for breast cancer.
K. Hemminki (2004)
Trends in Breast Cancer by Race and Ethnicity: Update 2006
Carol Smigal (2006)
The Swedish Family‐Cancer Database 2009: prospects for histology‐specific and immigrant studies
K. Hemminki (2010)
Trends in epidemiology and management of breast cancer in developing Arab countries: a literature and registry analysis.
N. E. El Saghir (2007)
Rapidly rising breast cancer incidence rates among Asian‐American women
D. Deapen (2002)
Clinical practice. Breast-cancer screening.
E. Warner (2011)
Age-period-cohort modelling of breast cancer incidence in the Nordic countries.
K. Rostgaard (2001)
BREAST FEEDING TRENDS AND RECENT INFORMATION ACTIVITIES IN SWEDEN
Y. Hofvander (1979)
Identifying population-based approaches to lower breast cancer risk
L. Bernstein (2008)
Pubertal Development of Turkish Children
S. Semiz (2008)
Do immigrants have an increased prevalence of unhealthy behaviours and risk factors for coronary heart disease?
M. Gadd (2005)
Part I: Cancer in Indigenous Africans--burden, distribution, and trends.
D. Parkin (2008)
Cancer risks in first‐generation immigrants to Sweden
K. Hemminki (2002)
Effects of screening for breast cancer on its age‐incidence relationships and familial risk
K. Hemminki (2005)
Country of birth and body mass index: A national study of 2,000 immigrants in Sweden
P. Wändell (2004)
Breast cancer risk in women who fulfill high-risk criteria: at what age should surveillance start? Breast Cancer Res Treat 2010;121:133–141
A Brandt (2010)
Sociodemographic predictors of non-attendance at invitational mammography screening – a population-based register study (Sweden)
M. Lagerlund (2004)
Breast cancer risk in women who fulfill high-risk criteria: at what age should surveillance start?
A. Brandt (2009)
Effects of reproductive and demographic changes on breast cancer incidence in China: a modeling analysis.
E. Linos (2008)
Breast Cancer in Iran: An Epidemiological Review
Seyed Mohsen Mousavi (2007)
Lactation and incidence of premenopausal breast cancer: a longitudinal study.
A. Stuebe (2009)
Cancer in migrants to Australia: extending the descriptive epidemiological data.
A. Mcmichael (1988)
Hereditary breast and ovarian cancer in Asia: genetic epidemiology of BRCA1 and BRCA2
A. Liede (2002)
Studies of cancer in migrants: rationale and methodology.
D. Parkin (1996)
Breast Cancer in Chinese Women Younger than Age 40: Are They Different from Their Older Counterparts?
A. Kwong (2008)
Risk factors for breast cancer in Chinese women in Shanghai.
J. Yuan (1988)
Age at menarche of European, Afro-Caribbean and Indo-Pakistani schoolgirls living in London.
S. Ulijaszek (1991)
The nation-wide Swedish family-cancer database--updated structure and familial rates.
K. Hemminki (2001)
Breast cancer incidence in South Africa.
D. Vorobiof (2001)
Demographic and epidemiologic features of female adolescents in Turkey.
K. Vicdan (1996)
Risk of obesity in immigrants compared with Swedes in two deprived neighbourhoods
J. Faskunger (2009)
Region of birth, income and breastfeeding in a Swedish county
T. Wallby (2009)
Tumours of the breast and female genital organs
F Tavassoli (2003)
C. Fox (1979)
Migration patterns and breast cancer risk in Asian-American women.
R. Ziegler (1993)
Age of onset in familial cancer.
A. Brandt (2008)
The effect of changes in population characteristics on breastfeeding trends in fifteen developing countries.
L. Grummer-Strawn (1996)
Growth & development of Indian children adopted in Sweden.
L. Proos (2009)
Cancer Incidence in Five Continents
Freddie Ian Bray (1970)
This paper is referenced by
Female breast cancer incidence among Asian and Western populations: more similar than expected.
H. Sung (2015)
Triple-negative breast cancer risk in women is increasing by the loss of estrogen supply or by defective estrogen signaling
Z. Suba (2014)
Cancer in immigrants as a pointer to the causes of cancer.
K. Hemminki (2014)
Ethnic differences in breast cancer risk and survival: A study on immigrants in Sweden
Seyed Mohsen Mousavi (2013)
Trends in mortality after cancer diagnosis: A nationwide cohort study over 45 years of follow-up in Sweden by country of birth.
G. Abdoli (2015)
Improving breast cancer detection using ultrasonography in asymptomatic women with non-fatty breast density
P. Korpraphong (2014)
Breast cancer in Bedouin-Arab patients in southern Israel: epidemiologic and biologic features in comparison with Jewish patients.
I. Lazarev (2014)
Cancer risk in different generations of Middle Eastern immigrants to California, 1988–2013
C. Ziadeh (2017)
Cancer mortality and survival after cancer diagnosis by migration background and socioeconomic position in Sweden
Gholamreza Abdoli (2017)
Imaging surveillance programs for women at high breast cancer risk in Europe: Are women from ethnic minority groups adequately included? (Review).
K. Belkic (2015)
Epidemiologic and Clinical Profiles of Breast Diseases in Niger
Harouna Zouladeny (2015)
Demographic survey of four thousand patients with 10 common cancers in North Eastern Iran over the past three decades.
Zahra Nikfarjam (2014)
Localization of Epstein-Barr virus to infiltrating lymphocytes in breast carcinomas and not malignant cells.
G. Khan (2011)
Survival analysis of breast cancer patients in northwest Iran.
J. E. Ziaei (2013)
Breast Cancer Challenges and Screening in China: Lessons From Current Registry Data and Population Screening Studies.
Qing-Kun Song (2015)
Dysparities between African-American and White American Women in Breast Cancer Incidence and Mortality
Z. Suba (2014)
Rising global burden of breast cancer: the case of sub-Saharan Africa (with emphasis on Nigeria) and implications for regional development: a review
Samuel O. Azubuike (2018)
Age‐ and time‐dependent changes in cancer incidence among immigrants to Sweden: colorectal, lung, breast and prostate cancers
Seyed Mohsen Mousavi (2012)
The Epidemiology of Breast Cancer in Oman
Shamsa Al Farsi (2014)
Age of diagnosis of breast cancer in china: almost 10 years earlier than in the United States and the European union.
Qing-Kun Song (2014)
Cancer incidence among Turkish, Chilean, and North African first-generation immigrants in Sweden compared with residents in the countries of origin and native Swedes
Seyed Mohsen Mousavi (2013)
Baseline staging tests based on molecular subtype is necessary for newly diagnosed breast cancer
X. Chen (2014)
Breast cancer screening utilization among Eastern European immigrant women worldwide: a systematic literature review and a focus on psychosocial barriers
V. Andreeva (2013)
Cytomorphologic patterns of breast lesions in Sudanese patients: lessons learned from fine needle aspiration cytology.
A. Almobarak (2014)
CÂNCER EM ADULTOS JOVENS (20-39 ANOS) EM FORTALEZA: TENDÊNCIAS EM INCIDÊNCIA, MORTALIDADE E SOBREVIDA, 1997-2006
Miren Maite (2012)
Triple-negative breast cancer risk in women is defined by the defect of estrogen signaling: preventive and therapeutic implications
Z. Suba (2014)
Cancer incidence, trends, and survival among immigrants to Sweden: a population-based study
Seyed Mohsen Mousavi (2015)
Morbidity and mortality in gynecological cancers among first‐ and second‐generation immigrants in Sweden
Seyed Mohsen Mousavi (2012)
Determinants of breast cancer in Saudi women from Makkah region: a case-control study (breast cancer risk factors among Saudi women)
F. Alsolami (2019)
Breast cancer by migrant background in Belgium: Lower risk, but worse survival in women of non‐European origin
W. M. J. Van Hemelrijck (2019)
Aportación al estudio de la edad de aparición en adultos de los diferentes tipos de cáncer
M. Pérez (2011)
Breast cancer trends in Israeli Jewish and Arab Women, 1996–2007
L. Keinan-Boker (2013)See more